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Men fart more when eating a plant-based diet due to good gut bacteria
10hMen fed a plant-based diet farted seven times more per day and had bigger stools than when they were on a Western diet because their “good” bacteria flourished
World Trade Center kollapsede og ændrede vores bygninger for altid
13hTerrorangrebet lærte os meget om, hvordan man kan sikre bygninger mod brand og eksplosioner.
Hvad skete der egentlig den 11. september 2001?
17hPLUS. Hvor er det fly, der ramte Pentagon, og hvordan styrtede den mystiske bygning 7 sammen? Ingeniøren har set på nogle af de mest sejlivede konspirationsteorier om begivenhederne den 11. september 2001.
LATEST
Unvaccinated People Are 11 Times More Likely To Die Of COVID-19, New Research Finds
1dThe COVID-19 vaccines continue to provide powerful protection, even against the delta variant, the CDC said. It also found that vaccinated people were 10 times less likely to be hospitalized. (Image credit: Chandan Khanna/AFP via Getty Images)
Hugh Laurie, Who Played Dr. House, Appears to Have Just Brutally Roasted Anti-Vaxxers
1dHugh Laurie, the actor best known from hit TV drama “House MD,” took to Twitter today to absolutely roast the anti-vaccination movement — or, at least, we’re pretty sure he did. “I find the injunction ‘think for yourself’ very stirring — until I remember that I could never have conceived of 99 percent of the concepts I rely on every day to survive,” a contemplative Laurie wrote . “I’m extremely g
mRNA cancer therapy now in human trials after shrinking mouse tumours
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10hMrna Cancer Therapy
An mRNA cancer treatment developed by BioNTech and Sanofi is being tested in people after shrinking tumours in mice, and is hoped to repeat the success of mRNA covid-19 vaccines
Quantum nature of gravity may be detectable with gravitational waves
10hPerhaps the most important problem in physics is how gravity and quantum mechanics fit together, and strange fluctuations in gravitational waves could help us figure it out
Listen to an Australian duck say ‘you bloody fool’ like a human
10hWhen raised in captivity, musk ducks learn to copy the sounds of human life around them, which shows that they are what’s known as vocal language learners like parrots and humans
What's the rarest blood type?
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1dCBC CML COVID Blood
Blood typing is particularly important for blood transfusions.
Så överlevde den utrotningshotade papegojan mot alla odds
18hInavel hotade den udda papegojan Kakapon som sedan tusentals år lever på öar utanför Nya Zeeland.
Prehistoric winged lizard unearthed in Chile
14hChilean scientists have announced the discovery of the first-ever southern hemisphere remains of a type of Jurassic-era "winged lizard" known as a pterosaur.
Researchers reconstruct major branches in the tree of language
1dThe diversity of human languages can be likened to branches on a tree. If you're reading this in English, you're on a branch that traces back to a common ancestor with Scots, which traces back to a more distant ancestor that split off into German and Dutch. Moving further in, there's the European branch that gave rise to Germanic; Celtic; Albanian; the Slavic languages; the Romance languages like
Yes, Gov. DeSantis, Studies Do Show Masks Curb Covid-19 In Schools
1dSeveral studies over the past year and a half have arrived at the same conclusion: mask wearing significantly limits transmission of the coronavirus in schools. (Image credit: kali9/Getty Images)
Why Federal Research Bolsters the Case for Coronavirus Vaccine Mandates
23hScientists believe the administration’s new measures may tamp down the pandemic, although the effects will not immediately be obvious.
Federal Research Bolsters the Case for Vaccine Mandates
23hScientists believe the administration’s new measures may tamp down the pandemic, although the effects will not immediately be obvious.
We have spotted a new kind of supernova triggered by cosmic collisions
10hWhen a neutron star or a black hole ploughs through a massive star, it can force the star to explode in a type of supernova that has now been observed for the first time
How domesticating the African baobab tree could secure its future
10hFarmers seldom plant the African baobab because it takes up to 23 years to fruit, but a team in Ghana has got the trees to flower in less than three years
NSW Covid crisis: Brad Hazzard defends end to daily press conferences as cases and death toll worsen
17hNSW records 1,599 new coronavirus cases and eight more deaths, while ACT chief minister Andrew Barr reports 15 new infections Follow the Australian Covid blog Qld Covid update: five new cases as Annastacia Palaszczuk flags possible lockdown Restrictions: NSW ; Vic ; borders NSW Covid vaccination rate by postcode – check your suburb Vaccine rollout tracker ; get our free news app ; get our morning
We Now Know Why There Are Dead Galaxies Floating Lost in The Void of Space
20hThey didn't spin out from nowhere.
Genetics Papers Retracted Over Human Experimentation Scandal
1dTwo genetics papers that had been published in prominent academic journals have been retracted in response to criticism that their subjects — persecuted Muslim Uyghurs from China — hadn’t fully consented to the process. The studies reveal a bleak trend in which members of Chinese law enforcement or public security officials are listed as coauthors on genetics research papers, suggesting that the
Virgin Galactic Dumped $500 Million in Stocks Before Bad News Dropped
1dPilots in control of the suborbital plane that took Virgin Galactic founder Richard Branson high into the upper atmosphere earlier this summer had to make a split second decision. A beeping red light alerted them to a deviation of their planned trajectory, but they forged ahead at three times the sound of speed. As revealed in a New Yorker piece several weeks later, the flight did not go entirely
Phony Diagnoses Hide High Rates of Drugging at Nursing Homes
6hAt least 21 percent of nursing home residents are on antipsychotic drugs, a Times investigation found.
Parents Find Ways to Get Their Youngest Children Covid Vaccines
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6hParents Under 12 Covid
Schools have reopened around the country, and families with those under 12 are finding ways to get their kids inoculated, even though they’re not officially eligible yet.
A US military robot ship has fired a large missile for the first time
10hThe US Department of Defense has released footage of an uncrewed ship firing a large missile, in a demonstration of its Ghost Fleet Overlord programme, an initiative to develop robot vessels that can operate alongside crewed warships
Texas cold crisis early this year linked to melting Arctic sea ice
10hThe extreme cold snap that left millions without power in Texas early this year may have been made more likely due to melting Arctic sea ice, according to a scientific model
Cartilage from the nose used to treat two people's knee osteoarthritis
10hTwo people with severe knee osteoarthritis have been successfully treated by inserting cartilage harvested from their noses into their damaged joints
Wild cockatoos make utensils out of tree branches to open fruit pits
10hIn Indonesia, Goffin’s cockatoos have been seen whittling tools such as wedges and scoops that help them break into the pits of sea mangoes
Milkweed butterflies tear open caterpillars and drink them alive
11hThese ghastly meals provide male butterflies with chemicals that they use to produce mating pheromones, which female butterflies find irresistible.
SpaceX Space Tourists Say Elon Musk Has Barely Talked to Them
1dCerebral Guy It’s set up to be a historic moment: a crew of four civilians are about to rocket into space on board a SpaceX Crew Dragon capsule. The launch, dubbed Inspiration4, could soon mark the first time an all-non-professional team has ever gone for a trip around the Earth. Interestingly, SpaceX CEO Elon Musk isn’t exactly basking in the limelight ahead of Wednesday’s launch. According to I
Don’t Believe the Salad Millionaire
1dJonathan Neman really seemed to think he was onto something. Last week, in a lengthy, now-deleted post on LinkedIn, the CEO and co-founder of the upscale salad chain Sweetgreen expounded on a topic that might seem a little far afield for a restaurant executive: how to end the pandemic. “No vaccine nor mask will save us,” he wrote. (The vaccines, it should be noted, have so far proved to be near-m
A Flawed, Strange Covid-19 Origin Theory Is Gaining Traction
9hA spate of studies claim that the disease was circulating in Italy long before the pandemic—but they struggle to support the theory.
LA Police Are Collecting Detainees' Social Media Information
10hAccording to new documents, officers ask people they stop for their Facebook and Twitter account details, and then feed the data into Palantir.
58 per cent of oil must stay in the ground to meet 1.5°C climate goal
10hEnergy companies and nations must leave nine tenths of Earth’s coal and almost two thirds of its known oil and gas in the ground if the world is to hold temperatures to a target beyond which climate change’s impacts are dangerously amplified, researchers have calculated.
Male bigfin reef squid may be the best fathers of all cephalopods
10hSquids aren’t known for good parenting, mostly because they usually die after mating, but male bigfin reef squid check nests for potential predators and warn other males to stay away
Should we ban space weapons to stop the huge space junk problem?
10hA group of experts are calling for a ban on anti-satellite weapons tests because the debris they could create may threaten other satellites or even make parts of Earth’s orbit unusable
Climate change linked to risk of viruses jumping species in the Arctic
10hClimate change may increase the risk of viruses infecting new hosts in the Arctic, suggests a study of genetic material from an Arctic lake
Woman loses ability to feel hungry after stroke damages her brain
10hA young woman who lost the sensation of hunger after a stroke may help to explain one of the most mysterious areas of the brain and lead to new treatments for obesity
What Is Larry Elder Running For?
11hLarry Elder becoming governor of California would be a little like Bernie Sanders winning a Senate seat in Kansas, or Alexandria Ocasio-Cortez representing suburban Mississippi in the House, or Mike Pence ending his career as the mayor of Portland, Oregon. Yet in less than a week’s time, there’s some chance, albeit a diminishing one, that it might happen. Elder, a conservative talk-radio host fro
Google is shutting down controversial data-sharing project with NHS
10hGoogle is shutting down its controversial Streams app, which used machine learning to analyse medical records and was found to have failed to comply with UK data protection laws
Large Hadron Collider sticks with reels of tape for vast storage needs
10hThe physicists at CERN still rely on tape for the long-term storage of data from the LHC, because it is more reliable and cheaper than hard discs or flash storage
Hurricane Ida was almost certainly made worse by climate change
10hScientists say Hurricane Ida, which reached wind speeds of 241km/h, killed at least one person and left more than a million people without power, was almost certainly made worse because of climate change
Will PayPal's adoption of bitcoin make cryptocurrency more mainstream?
10hPayPal will now allow customers to buy and sell four cryptocurrencies, which could make it more useful for everyday life. Is this the moment when cryptocurrencies become mainstream?
A decade after she died, I can finally grieve the Amy Winehouse I knew and loved
8hComing to terms with the loss of my friend Amy Winehouse, amid the media frenzy that surrounded her death, has taken me 10 years God knows what I must have looked like: a bedraggled 25-year-old dressed as a psychedelic game hunter with glitter smeared across my face crying hysterically in a Cambridgeshire field. It was 4pm on 23 July 2011, and a friend of mine had broken the news to me: Amy was de
Black holes just got much more complicated thanks to quantum pressure
10hBlack holes were once thought not to have pressure, but a new set of quantum calculations has found that they may have some at their edges, which was completely unexpected
Blood test could reveal who is most likely to get severe covid-19
10hA simple blood test could help predict which people with covid-19 are likely to get severely ill and need to go on a ventilator
Rare kakapo parrot is genetically healthy despite being very inbred
10hThe kakapo, a critically endangered flightless parrot native to New Zealand, is in better genetic health than expected due to long isolation
Wooden robot arm is powered by plastic muscles
10hA new polymer that stores energy when it is stretched and deformed has been used as an artificial muscle to bend the elbow joint of a simple wooden robot
Gene responsible for cat fur patterns could lead to designer pets
10hResearchers have discovered the genetic basis for the different patterns of fur seen in domestic cats, but caution against the idea of using this to create pets with specific coats
Will the Texas abortion ban spread across the US?
10hOne of the most extreme abortion laws in the US went into effect on 1 September in Texas. What does it say, and could this type of law be passed in other US states?
Zebras rolling in pits help give life to the Namib desert in Africa
10hRolling on the ground seems to be essential to life – at least in Africa’s Namib desert, where zebras bathe in dust, creating pits in the landscape that promote biodiversity
Cavalier King Charles spaniels carry a high number of harmful genes
10hA genetic study of eight dog breeds including German shepherds and golden retrievers found that cavalier King Charles spaniels had the highest number of potentially harmful mutations
The history of the Large Magellanic Cloud has been mapped in detail
10hAstronomers have mapped the history of one of the nearest galaxies, the Large Magellanic Cloud, in more detail than ever before, showing when its stars formed
Detox Diets That Rid Your Body of 'Toxins' Are Not All They're Cracked Up to Be
17hThey have downsides, too.
It Worked! NASA’s Mars Rover Definitely Scooped up Rock Samples This Time
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23hNASA Perseverance Mars
Mission Complete Huge news: NASA confirmed that its Mars-rock-scooping robot, Perseverance, has at long last managed to scoop up some Mars rocks. That also means that the rover has started to conduct some rudimentary geological research on its surroundings, according to a NASA press release . While the bulk of the study will be conducted once those and any future samples make their way back to Ea
Even tiny green spaces in cities help urban wildlife biodiversity
10hGreening parts of cities is widely promoted as boosting biodiversity, health and well-being, and now researchers have found that improving even tiny green spaces leads to big increases in biodiversity
Covid-19 news: UK approves Pfizer and AstraZeneca booster shots
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10hCovid UK England Israel
The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic
Tooth decay has been a problem for primates for 54 million years
10hMicrosyops latidens, a prehistoric primate that lived about 54 million years ago, had dental cavities – perhaps because it had a taste for fruit and other sugar-rich food
What we know so far about booster shots and the covid-19 vaccines
10hSome countries are already pushing ahead with covid-19 vaccine booster programmes, but rapidly rolling out third shots in wealthy countries isn’t necessarily the best plan
Half-metre-long predator was giant of the seas 500 million years ago
10hMost animals that lived in the Cambrian period were small enough to rest comfortably in the palm of your hand – but Titanokorys was much bigger
Polar bears in Svalbard archipelago are inbreeding due to sea ice loss
10hAs global warming causes Arctic ice to melt away, archipelago-based polar bears are having more difficulty reaching each other, resulting in inbreeding
Foam from frogs' nests could help make bandages that release drugs
10hThe foam that some frogs produce to make nests can keep its shape for more than a week and can slowly release drugs for days, which means it could find a use in medicine
Some animals are evolving new body shapes as the climate changes
10hSome endotherms, commonly called warm-blooded animals, have grown larger wings, beaks or tails to increase their surface area, which helps them stay cool as the world warms
High-res carbon emission maps reveal climate impact of commuting
10hHigh-resolution maps of carbon emissions have revealed how our day-to-day patterns of behaviour, such as commuting, affect the release of greenhouse gases, and could help governments quickly see the impact of green policies
Call centre workers can use AI to mimic your accent on the phone
10hAI software can detect the accent of a person on one end of an online or telephone conversation and modify the accent of a responding person to match it in real time, which could help with clarity in a range of interactions, including customer support, education and telemedicine
Mix-and-match antibiotic prescriptions may help lower resistance risk
10hAntibiotic resistance might be reduced if doctors instruct people to alternate between three different antibiotic medicines daily, tests with cells in the lab suggest
Stingrays’ bulging eyes and mouths make them much faster swimmers
10hStingrays have protruding eyes and mouths, which seem like they would make swimming less efficient, but they actually create vortices that let the rays swim faster
Rapidly evolving bits of DNA helped develop the human brain
10hSome sections of the human genome have changed quickly during our evolution, and hundreds of them seem to be involved in the development of our brains
Humans reached Arabia in at least five waves thanks to wetter climates
10hA single Arabian archaeological site has been occupied by ancient humans on five separate occasions over the past 400,000 years, each enabled by a period of wet climate
Scorpions have strange joints that can simultaneously bend and twist
10hScorpions have unusual joints in their tails that can twist and bend at the same time, and this design could be used for flexible robots
AI accurately identifies whether objects can be recycled from a glance
10hA neural network trained on a dataset of images can identify recyclable objects with more than 95 per cent accuracy using a standard webcam
America Played Into Al-Qaeda’s Hands
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13hal-Qaeda 9/11 Taliban
Alex Majoli / Magnum The United States today does not have so much as an embassy in Afghanistan, Iran, Libya, Syria, or Yemen. It demonstrably has little influence over nominal allies such as Pakistan, which has been aiding the Taliban for decades, and Saudi Arabia, which has prolonged the conflict in Yemen . In Iraq, where almost 5,000 U.S. and allied troops have died since 2003, America must en
Mars rocks collected by Perseverance boost case for ancient life
14hNASA's Perseverance Mars rover has now collected two rock samples, with signs that they were in contact with water for a long period of time boosting the case for ancient life on the Red Planet.
Image: Hubble captures a sparkling cluster
14hThis star-studded image from the NASA/ESA Hubble Space Telescope depicts NGC 6717, which lies more than 20,000 light-years from Earth in the constellation Sagittarius. NGC 6717 is a globular cluster, a roughly spherical collection of stars tightly bound together by gravity. Globular clusters contain more stars in their centers than their outer fringes, as this image aptly demonstrates; the sparsel
Epic Leaves a Big Crack in Apple’s Walled Garden
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1dEpic Apple App Store
A judge ordered significant changes to the App Store today, but the fight between Epic Games and Apple isn't over yet.
Elizabeth Holmes Is on Trial. Silicon Valley Is Watching
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11hHolmes Theranos Balwani
“I’m glad the ‘Fake it till you make it’ mantra of Silicon Valley is coming into question,” one investor told WIRED.
Amazon fires have affected almost all the region's endangered species
10hFires set in the Amazon to clear land for farming have affected almost all the endangered species in the Amazon rainforest, cutting down on animal habitats and threatening plant species
What ancient money tells us about the future of computers
10hThe way that some of the first coins were viewed 2500 years ago is similar to how we regard computers today, writes Annalee Newitz
Opioid levels in US wastewater spiked during the early pandemic months
10hIn the early months of the covid-19 pandemic, wastewater samples from Kentucky and Tennessee had a 72 per cent increase in hydrocodone, plus spikes in antidepressants and anti-anxiety drugs
Digital archives meant to be permanent seem to be lost on the web
10hAn analysis of web archives of national libraries and public records offices found that some of the documents meant to be permanent are no longer discoverable when they are moved
AI can detect a deepfake face because its pupils have jagged edges
10hThe pupils of faces in computer-generated deepfake videos or images have more jagged edges and are less symmetrical than those in real human eyes
The Atlantic Daily: The Roe v. Wade Baby Tells Her Story
1dEvery weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox. Tracy Nguyen for The Atlantic In 1973, American women won the constitutional right to abortion through Roe v. Wade . But the Supreme Court’s ruling did not come in time for its anonymous plaintiff
Biggest DDoS Attack in History Hits Russian Tech Giant Yandex
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9hCVE-2018-13379
Plus: A TrickBot hacker arrest, a Fortinet VPN password leak, and more of the week's top security news.
The Third Revolution in Warfare
10hOn the 20th anniversary of 9/11, against the backdrop of the rushed U.S.-allied Afghanistan withdrawal, the grisly reality of armed combat and the challenge posed by asymmetric suicide terror attacks grow harder to ignore. But weapons technology has changed substantially over the past two decades. And thinking ahead to the not-so-distant future, we must ask: What if these assailants were able to
Watch a one-legged robot hop about as researchers try to knock it over
10hA one-legged robot that can stand, hop and keep its balance on sloping or unsteady surfaces could offer a cheaper route to bipedal bots and self-balancing exoskeletons
Illegal cannabis farms on the US west coast are poisoning wildlife
10hCannabis crops grown illegally on public lands along the west coast of the US are clashing with the habitats of native predators, putting wildlife at risk of poisoning from dangerous pesticides
How Math Solved the Case of the Volcanic Bombs That Didn’t Explode
13hScientists have long been puzzled by flying blobs of magma that remained intact, but didn’t have a good way to study them.
SpaceX Tourist Spacecraft Will Be Loaded With Dozens of NFTs
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1dKings Leon NFT TD SpaceX’s
Easy Lift Next week, the Inspiration4 mission, an all-civilian crew of space tourists, will careen into space on board a SpaceX Crew Dragon module. And flying with them will be dozens of non-fungible tokens (NFTs), according to Space.com , in an attempt to raise money for charity by capitalizing on the trendy digital certifications of authentication being bought, sold, and traded over the blockch
How Do Archaeologists Crack the Code of Dead Languages?
1dFrom the Rosetta stone to the Enigma Code, there are two main ways to decipher an extinct language, but artificial intelligence is helping to modify translations.
Will plans for new UK coal mine scupper net-zero ambitions at COP26?
10hThe fate of plans for the UK’s first deep coal mine in 30 years will be fiercely debated at a public inquiry starting tomorrow, in what is expected to be a landmark test case of what new fossil fuel projects should be allowed as countries act to hit net-zero emissions
Experts Warn of Rising Suicide Rates of Black Girls
1dResearchers have uncovered worrisome trends among Black youth.
A Third of Shark and Ray Species May Face Extinction
10hOverfishing, habitat loss, and climate change are driving species collectively known as chondrichthyan fishes toward a global crisis.
First full survey of Peru and Chile’s threatened fog island ecosystems
10hSo-called fog oases along the dry coast of Peru and Chile are home to medicinal plants – and a survey suggests they can grow in an area four times greater than previously thought
Scorpions develop a sting in the tail before they are ready to use it
10hNewborn scorpions produce and store venom in their tail, or telson, despite not being able to use it until they have shed their first exoskeleton
These Apps Saved My Sanity (and Probably My Marriage)
11hTalking about tech at home is usually all about “smart” gear, but in this case, some simple programs made all the difference in my—and my family's—life.
Shipping has made slow progress on climate change – can methanol help?
10hMaersk, the world’s biggest shipping company, has ordered eight ships capable of running on methanol, which could prove a crucial route to helping the shipping industry decarbonise
New research integrates the most effective practices for eye tracking in AR eyewear
1dThe eyes have it. They are constantly on the move when viewing scenes in augmented reality (AR).
GitHub's AI programming assistant can introduce security flaws
10hAI that automatically generates source code to help human programmers complete projects has been found to include bugs or security flaws in up to 40 per cent of the code it outputs
Wildfire pollution linked to at least 33,000 deaths worldwide
10hWildfires akin to those that visibly devastated parts of Greece, Siberia and North America this year are also invisibly taking a deadly toll on human health
Why the UK doesn't need a new coal mine
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10hSwedish AEP UK Steel
The UK is considering opening a new coal mine – here's why it doesn't need one, says Mark Peplow
A year that changed the world – and medical companies’ fortunes
7hWhile Covid sent many firms to the wall, others prospered by spotting opportunities, from test kits to mask coatings The pandemic has taken a heavy toll on business, gutting high streets as familiar names fell into receivership. But for some less well-known firms, the past 18 months have been transformational. Those that have thrived did so by carving out a new niche – with products as varied as
A glimpse at Greenland's deep-sea ecosystems threatened by fishing
10hHalibut fishing off the coast of Greenland uses heavy equipment dragged along the sea floor, which can cause irreversible harm to slow-growing anemones and coral
Almost no one encrypts their emails because it is too much of a hassle
10hA study looking at the use of encryption to keep the contents of an email private has found that the technology is rarely used, despite being available for decades
11h
Why don't poisonous animals die from their own toxins?
11hSome animals, such as poison dart frogs, carry enough toxic chemicals to kill multiple adult humans, but they've evolved tricks to avoid poisoning themselves.
How to Grab a Screenshot on Any Device
10hLearn how to capture your screen for posterity and share that crazy text or high score.
The toxic error at the heart of efforts to curb heavy metal pollution
10hEnvironmental limits on dangerous metals like mercury and lead shouldn't just keep humans safe, but other animals too, say Coline Monchanin and Mathieu Lihoreau
No, there's nothing wrong with seedless fruits
10hThere is an increasing number of people who think seedless fruits are bad for you, but actually the opposite is true, writes James Wong
Covid-19 dashboard: Cases, deaths and vaccinations
10hThis interactive dashboard tracks the world’s recorded covid-19 cases and deaths, plus vaccines administered
Perseverance rover collects 2nd Mars sample (photos)
8hPerseverance collected another drilled-out core of a Martian rock dubbed "Rochette," sealing the sample in its designated titanium tube on Wednesday (Sept. 8).
Radioactive rhino horns may deter poachers in S.Africa
14hSouth African scientists are studying ways to inject radioactive material into rhino horns to make them easier to detect at border posts, a move to discourage poaching, a researcher said on Friday.
Mammals Carry a Graveyard of Viruses in Our DNA, And It Could Have a Crucial Purpose
42minAncient vaccinations.
What will the future of computers be like ?
2hI'm not interested in a definite date, I'm interested in all of the foreseeable future of computers but please don't hesitate to comment any relevant input. submitted by /u/ounurrs [link] [comments]
To prepare society for the demands of the future, institutions must equip tomorrow’s leaders to be “AI bilingual”.
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Improved water management system for toxic textile effluents developed
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New mRNA treatment for Cancer shows promising trial results in mice
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BMW’s game-changing e-bikes could revolutionise how we get to work
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Why Apple and Google are moving into solar energy
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The glove that transmits ‘touch’ over the internet
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Illegal Sand Mining Is Ruining These Countries' Ecosystems
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Sophia the Robot will be mass-produced this year
3hThis article was originally published on our sister site, Freethink. When Sophia the robot debuted in 2016, she was one of a kind. She had a remarkably lifelike appearance and demeanor for a robot, and her ability to interact with people was unlike anything most had ever seen in a machine. Since then, Sophia has spoken to audiences across the globe (in multiple languages), been interviewed on cou
Rumskibe på én kilometer: Kina vil sende supertankere i rummet
3hDe gigantiske fartøjer kan blandt andet fragte mennesker til Mars i fremtiden.
The Atlantic Daily: 20 Years of Grief
6hTomorrow marks 20 years since the attacks on September 11, 2001. The adrenaline shock of that morning has long worn off, leaving behind only the horror, the loss, and two decades’ worth of grief. It’s tempting to use this anniversary to consider the attacks as a greater political or cultural moment, to analyze where the country went right or wrong in its response. And doing so is important. But f
Facebook AI Introduces GSLM (Generative Spoken Language Model), A Textless NLP Model That Breaks Free Completely of The Dependence on Text for Training
6hsubmitted by /u/izumi3682 [link] [comments]
Growing risk of once-in-a-century solar superstorm that could knock out internet, study says
6hsubmitted by /u/WestEst101 [link] [comments]
States across American west see hottest summer on record as climate crisis rages
6hsubmitted by /u/MesterenR [link] [comments]
Migrating Birds Follow The Whims of The Wind When Flying Non-Stop Across The Sea
6hNo need for flapping.
This Modern Online Therapy Provider Will Help You Find Your Inner Calm
8hOutmoded social taboos notwithstanding, it’s now a matter of common sense that mental health is just as vital and important to a person’s wellbeing as physical health. But even though most of us know this to be true, it’s still not easy to find a good mental health therapist, and the obstacles to finding one remain stubbornly high. And if you have a medical condition or some other reason for not
In Hurricane Ida's wake, satellite images show oil slicks in Gulf of Mexico
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8hGulf Ida Louisiana
Satellite images capture aerial views of an oil spill in the Gulf of Mexico following Hurricane Ida's landfall on Aug. 29.
First 10 Minutes of Season 1 | Gold Rush: Winter's Fortune
8hStream Full Episodes of Gold Rush: discovery+ ► https://www.discoveryplus.com/show/gold-rush #Discovery #GoldRush #GoldRushWintersFortune Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Follow Us on TikTok: https://www.tiktok.com/@Discovery We're on Instagram! https://instagram.com/Discovery Join Us on Facebook: https://www.facebook.com/Discovery Follow Us on Twitter: https://twitter.com
This Week’s Awesome Tech Stories From Around the Web (Through September 11)
8hLONGEVITY Meet Altos Labs, Silicon Valley’s Latest Wild Bet on Living Forever Antonio Regalado | MIT Technology Review “Altos is pursuing biological reprogramming technology, a way to rejuvenate cells in the lab that some scientists think could be extended to revitalize entire animal bodies, ultimately prolonging human life. …The new company…is recruiting a large cadre of university scientists wi
Looking for Interstellar Monuments
8hAn ancient civilization from a distant star could have created immortal machines to roam the Milky Way and keep its legacy alive — Read more on ScientificAmerican.com
Weekend reads: A ‘hoax paper’ author resigns; Uyghur DNA papers retracted; a year without p values
9hBefore we present this week’s Weekend Reads, a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend Reads, and our daily work? Thanks in advance. The week at Retraction Watch featured: Introducing two sites that claim to sell authorships on scientific … Continue reading
Twenty years after 9/11, hindsight is 20/20
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9h9/11 20 Years
The 20th anniversary of 9/11 arrives with pessimism and a sense of defeat. 9/11 caused a national trauma that lasted for years. We should remember this when analyzing the mistakes that America made in its war on terrorism during the subsequent 20 years. As the 20th anniversary of the 9/11 terrorist attack approached, I was disappointed to see how negative the media coverage is. The overall report
Gamer beware, ultra-realistic VR is a philosophical minefield for humanity
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David Sinclair: Reverse Aging & Extend Your Lifespan, Interview by Mayim Bialik
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Why has El Salvador officially adopted bitcoin as its currency?
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10hEl Salvador Bitcoin
El Salvador is the first country to adopt the cryptocurrency bitcoin as legal tender, but other nations may follow suit
Will China's algorithm crackdown serve its citizens or the state?
10hChina has drafted powerful new legislation that would control how businesses use data to target advertising, curate social media feeds and recommend content
We finally have the tools to build a net-zero world
10hToday, many of the technologies required to decarbonise society are ready to be put in place – and the costs of shifting to net zero must be weighed against the price of inaction
Quantum theory continues to challenge our conception of reality
10hIt's hard to overstate just what a seismic shift quantum mechanics has brought about over the past century and its ongoing mysteries are a gift that is still giving
We need to fully explore the planet to understand our species' origins
10hThe study of human evolution has neglected huge areas of Earth, and recent discoveries from Arabia suggest these places have a lot to tell us
The term 'AI' overpromises: Here's how to make it work for humans instead
11hOne of the popular memes in literature, movies and tech journalism is that man's creation will rise and destroy it. Lately, this has taken the form of a fear of AI becoming omnipotent, rising up and annihilating mankind. The economy has jumped on the AI bandwagon; for a certain period, if you did not have "AI" in your investor pitch, you could forget about funding. (Tip: If you are just using a G
The 18 Best Weekend Deals on Headphones, Games, and Sex Toys
11hFall is around the corner. It's time to get into some cozy indoor activities.
Porsche and Siemens break ground on low-carbon e-fuel plant in Chile: Electrolyzed hydrogen is combined with CO2 to make methanol, then gasoline.
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AI can make better clinical decisions, treating behavioural problems, than humans, with fewer decision-making errors. But the goal is use AI to facilitate the work of professionals, not actually replace them
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Hi! In the latest video of my behavioral science explainer series, Go Nudge Yourself, I look at the anchoring effect – our tendency to rely too heavily on an initial reference point or 'anchor' while making a decision. Check it out and support the channel by subscribing if you like it.
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Storm Olaf drenches Mexico's Baja California
14hTropical storm Olaf swept across Mexico's Baja California peninsula on Friday, bringing strong winds and heavy rain to the major beach resorts of Los Cabos before losing its hurricane force.
Nature congress calls for protecting 30% of Earth, 80% of Amazon
14hThe world's most influential conservation congress passed resolutions Friday calling for 80 percent of the Amazon and 30 percent of Earth's surface—land and sea—to be designated "protected areas" to halt and reverse the loss of wildlife.
Zoo Atlanta: Positive virus tests among gorilla population
14hSeveral members of a troop of western lowland gorillas at Zoo Atlanta have tested positive for the coronavirus after handlers noticed many of the great apes were showing signs of mild coughing, runny noses and a small loss of appetite, the zoo said Friday.
California firefighters chase new fires ignited by lightning
14hFirefighters scrambled Friday to quash fires ignited by lightning as thunderstorms with mostly small but welcome amounts of rain rumbled across drought-stricken Northern California, where forests have been burning for weeks.
Can a vaccine help fight the opioid epidemic? A clinical trial aims to find out
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20 år sedan 11 septemberattackerna
16hIdag, 11 september 2021, är det precis tjugo år sedan attackerna mot USA, iscensatta av terrororganisationen al Qaeda. Fyra passagerarplan kapades och användes som självmordsmissiler mot mål i USA. De … Continued Inlägget dök först upp på Vetenskap och Folkbildning .
Gåtan med bronsålderns tomma gravar
16hTre flacka höjder i åkerkanten, på håll tämligen oansenliga. Men här skulle arkeologerna komma att göra häpnadsväckande fynd inför bygget av nya E18 förbi Enköping. Inte i form av guld och ädla stenar eller monument. Nej, vid Nibble fann de den kanske största kultplats från bronsåldern som grävts ut i Skandinavien.
20 år siden: Terrorangrebet, der rystede verden
17hPLUS. Da to kaprede fly ramte World Trades Centers tvillingetårne, der siden sank i grus, indvarslede det en ny tid med frygt, krig mod terror og konspirationsteorier. Ingeniøren fulgte katastrofen minut for minut.
Nekrolog over privacy: De to tårne tog privatlivet med sig i gruset
17h11. september har med sin gru og den efterfølgende krig mod terror skabt et paradigmeskift i holdningen til masseovervågning.
2001: Varmen fik World Trade Center til at kollapse
17hStatiker mener ikke, at flyene eller antændingen af flybrændstoffet i sig selv gjorde væsentlig skade på de to tårne. Men da varmen fra branden ødelagde de bærende konstruktioner, var katastrofen en realitet.
A spoonful of sugar opens a path to longer lasting lithium sulfur batteries
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Enzyme could be major driver of preeclampsia
20hA new study indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine. The finding could lead to new treatments for preeclampsia other than premature delivery, which is often the only option.
What the brain shows: The benefits of virtual reality in creative arts therapies
20hResearchers examined the differences in prefrontal cortex (PFC) activation between two distinct drawing tasks in virtual reality. Results of the study indicated significant differences between a rote tracing task and a creative self-expression task, with the rote tracing task showing an increase in PFC activity. It also showed there was reduced PFC activation for creative self-expressive tasks, in
People with Parkinson's may benefit from seven walking strategies
20hVarious strategies can help people with Parkinson's who have difficulty walking, but a new study finds that many people have never heard of or tried these strategies. The study also found that how well different compensation strategies worked depended on the context in which they were used, such as indoors versus outdoors, under time pressure or not.
Potential indicator for obesity risk detected during sleep
20hResearchers have shown that people with inflexible metabolisms burn less fat at night than those with flexible metabolism. The team measured the respiratory quotient throughout the night and found that despite equal ages, BMIs, and amount of fat, people with inflexible metabolisms burned more carbohydrates and less fat than did people with flexible metabolisms. The higher sleep-time quotient could
Limiting screen time for young adults after concussion results in shorter duration of symptoms
20hNewly published research shows that young adults who limited screen time for 48 hours immediately after suffering a concussion had a significantly shorter duration of symptoms than those who were permitted screen time.
No serious COVID-19 vaccine side effects in breastfeeding moms, infants, study finds
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20hCovid Breastfeeding
Researchers found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.
Forest fires linked to tens of thousands of avoidable deaths
20hSetting fire to forest and agricultural land in Southeast Asia to prepare it for cultivation or grazing causes air pollution that is contributing to an estimated 59,000 premature deaths a year, according to a new study.
New information on the early stages of dementia with Lewy bodies
20hResults from a new study reinforce the notion that dementia with Lewy bodies can be pathologically classified into two different disease types.
Newly developed software unveils relationships between RNA modifications and cancers
21hResearchers have developed a software called ModTect that can help reveal the relationships between RNA modifications and the development of diseases and disorders. Their work highlights the potential of using RNA modifications as biomarkers to test for diseases.
New ways to improve the science of ‘trade-offs’
21hResearchers working on complicated problems in agriculture, ecology and medicine have developed a mathematical model to enable faster solutions.
Interfacing stretchable circuits for deformable devices and displays
21hResearchers have developed a stretchable anisotropic conductive film (S-ACF) for electrical interfacing in high-resolution stretchable circuits.
Impaired immune response may cause bone resorption in patients with genetic disorder
21hResearchers have determined that enhanced bone resorption activity due to a faulty immune response may underpin multifocal osteomyelitis — painful, chronic bone infections — in children with MSMD, a rare genetic condition resulting from a range of immune system mutations.
Zoning policies that boost affordable housing: Good for the heart?
21hInclusionary zoning policies that increase the supply of affordable housing may be good for the heart, according to new research. The study notes that such zoning programs were associated with lower rates of heart disease.
New study on COVID-19 vaccinations in the largest US cities finds stark inequities
21hIn a study of the nine largest U.S. cities, researchers found stark racial, ethnic, and socioeconomic inequities in COVID-19 vaccination rates across neighborhoods. The study showed that high vaccination neighborhoods had more white residents, fewer people of color, higher incomes, and lower poverty rates. These high vaccination neighborhoods also had lower historical COVID-19 death rates, showing
These Ridiculous Marsupials Start to Crawl Before They Even Grow a Single Bone
22hMoving, living jellybean-lings!
Israeli firm, StoreDot releases battery that charges fully in 10 minutes
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Race to build a ‘Sun on Earth’: Magnet capable of lifting an aircraft carrier arrives in France
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Tesla Patented Laser Wipers to Blast Bird Poop off of a Vehicle's Windshield
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Researchers uncover way to reduce PC, phone energy consumption
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Object Close to the Center of Our Galaxy Is Emitting Radio Waves
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Learning by doing: How the brain's motor system can support vocabulary learning
23hNeuroscientists present new findings on how the motor cortex can help learn foreign vocabulary more quickly. The new data suggests that learning techniques that involve the performance of gestures instead of simple audio or visual information can benefit learners.
Transforming marine biodiversity discovery and monitoring
23hA new system for sampling fragments of DNA from marine organisms drifting in the ocean is set to create new opportunities for research on biodiversity and ways of supporting conservation activities. The results showed the ferry-collected samples had traces of DNA from all parts of the vertebrate ecosystem, ranging from small prey fish at the base of the food chain, such as anchovies and sardines,
Scientists discover that taste cells can control a whole animal’s foraging strategy
1dNeuroscientists have developed a computer model to explain how a nematode worm searches for food, revealing that single brain cells can both sense the environment and control a whole animal's foraging strategy. The study involved the microscopic nematode species, Caenorhabditis elegans.
Behind the scenes, brain circuit ensures vision remains reliable
1dAs mice watched movies, neuroscientists watched their brains to see how vision could be represented reliably. The answer is that consistency in representation is governed by a circuit of inhibitory neurons.
Firefighter exposure to wildfire smoke compounds varies, depending on duties
1dEvery summer, wildfires rage across the western U.S., and wildland firefighters are tasked with putting them out. But in the process, they inhale smoke and all the compounds in it, which can be harmful at high amounts. Now, researchers have evaluated the presence of particulate matter and volatile organic compounds (VOCs) around firefighters actively combating blazes, finding the highest exposures
Combining sunlight and wastewater nitrate to make the world’s No. 2 chemical
1dEngineers have created a solar-powered electrochemical reaction that not only uses wastewater to make ammonia — the second most-produced chemical in the world — but also achieves a solar-to-fuel efficiency that is 10 times better than any other comparable technology.
Why do people with diabetes develop severe COVID-19?
1dThe enzyme SETDB2 is implicated in the development of runaway inflammation characteristic of severe COVID-19 in patients with diabetes who are infected with coronavirus.
The World's Oldest Known Forest Was Not Like We Imagined, New Study Shows
1dNestled across an ancient floodplain.
Reconfigurable metasurfaces provide nanoscale light control
1dResearchers have designed new metasurfaces using nanoscale techniques inspired by kirigami that could offer a new chip-based way to achieve nanoscale control of light, which could lead to better optical displays, information encoding and digital light processing.
A recent reversal in the response of western Greenland’s ice caps to climate change
1dGreenland may be best known for its enormous continental scale ice sheet that soars up to 3,000 meters above sea level, whose rapid melting is a leading contributor to global sea level rise. But surrounding this massive ice sheet, which covers 79% of the world's largest island, is Greenland's rugged coastline dotted with ice capped mountainous peaks. These peripheral glaciers and ice caps are now
Disease genes help developing brains
1dIf the cerebral hemispheres of the forebrain fail to divide properly in an unborn child, this results in holoprosencephaly. A team has discovered candidate genes that can positively influence the severity of this congenital malformation of the forebrain.
Office air quality may affect employees’ cognition, productivity
1dThe air quality within an office can have significant impacts on employees' cognitive function, including response times and ability to focus, and it may also affect their productivity, according to new research.
GaN-on-diamond semiconductor material that can take the heat – 1,000 degrees to be exact
1dResearchers succeed in the direct bonding of diamond and gallium nitride (GaN) at room temperature and demonstrate that the bond can withstand heat treatments of 1,000 degrees Celsius, making it ideal for the high temperature fabrication process of GaN-based devices. GaN-on-diamond semiconductor material will allow for the next generation of high power, high frequency devices.
Surprisingly high emissions from fuel-powered auxiliary heaters in cars
1dFuel-powered auxiliary heaters can be significant sources of particulate emissions from vehicles, a new study shows.
Good sleep-time recovery is associated with a healthier diet and lower alcohol consumption
1dGood sleep-time recovery is associated with a health-promoting diet and health-promoting eating habits, as well as with lower consumption of alcohol, according to a new study investigating psychological and physiological well-being among working-age Finnish adults.
Hand pollination of crops is of major importance
1dPollinators — such as bees, butterflies and birds — are essential for agricultural production. However, natural pollination can also fail or be insufficient, which can lead to lower yields and poorer quality. This means alternative solutions are needed. Hand pollination, in which pollen is applied manually or mechanically to the flower, can supplement or replace pollination by animals. Researche
‘Anti-rust’ coating for plants protects against disease with cellulose nanofiber
1dResearchers have found that coating soybean plant leaves with cellulose nanofiber (CNF) gives protection against an aggressive fungal disease. The CNF coating changed leaf surfaces from water repellent to water absorbent, and suppressed pathogen gene expression associated with infection mechanisms, offering resistance to the destructive Asian rust disease. This is the first study to examine CNF ap
Putative Exercise Hormone Irisin Boosts Mouse Brainpower
1dMice lacking irisin didn’t exhibit the cognition improvements that typically follow exercise, and in mouse models of Alzheimer’s disease, treatment with the hormone reduced cognitive decline.
A Surge in Pandemic Research Shines a Spotlight on Preprints
1dMany scientists have turned to preprints to rapidly disseminate their research on COVID-19, but some disagree with this approach.
Engineered E. coli could make carbohydrates, renewable fuel, from CO2
1dResearchers from Newcastle University, UK have engineered Escherichia coli bacteria to capture carbon dioxide (CO2) using hydrogen gas (H2) to convert it into formic acid. The research, published today in Applied and Environmental Microbiology raises the possibility of converting atmospheric CO2 to commodity chemicals.
Pivotal climate summit dogged by COVID and equity concerns
1dNature, Published online: 10 September 2021; doi:10.1038/d41586-021-02465-y Environmental network calls for delay to the November meeting, but many developing countries and the host nation vow to press on in face of climate threats.
SpaceX's First Civilian Astronauts 'Underestimated' How Intense The Training Would Be
1dCould you do it?
The secret to how scorpions, spiders, and ants puncture tough skin
1dMany small animals grow their teeth, claws and other “tools" out of materials that are filled with zinc, bromine and manganese, reaching up to 20% of the material's weight. My colleagues and I call these “heavy element biomaterials," and in a new paper , we suggest that these materials make it possible for animals to grow scalpel-sharp and precisely shaped tools that are resistant to breaking, de
Transforming ‘sewer gas’ into clean hydrogen fuel
1dScientists have found a new chemical process to turn a stinky, toxic gas into a clean-burning fuel.
Food science meets cell science in bid to explain inner workings of membrane-free cell compartments
1dResearchers report that food science principles have helped them determine how unusual droplets within cells stay organized and avoid dissolving into the rest of the cell's gelatinous interior.
What are the ethics of getting a COVID-19 vaccine booster?
1dAfter the Biden administration’s announcement on COVID-19 booster shots, questions came up about the ethics of vaccinated people in the US getting a booster when so many people around the world are still waiting for their first dose. And while we’re pondering ethics, is there a selfish argument for the US to lead efforts to vaccinate people around the world? What about vaccine mandates? And when
Banishing bias across disciplines, genders and experience—new tool for fairer research metrics
1dh-index, g-index, i10 index, m-quotient, Journal Impact Factor, Altmetrics … it's long been an intractable issue plaguing the research community—how to assess the relative merits of research objectively across disciplines and make fair comparisons between early career and established researchers, different genders, and even different research disciplines.
Predator-induced maternal effects determine adaptive antipredator behaviors via egg composition [Evolution]
1dIn high-risk environments with frequent predator encounters, efficient antipredator behavior is key to survival. Parental effects are a powerful mechanism to prepare offspring for coping with such environments, yet clear evidence for adaptive parental effects on offspring antipredator behaviors is missing. Rapid escape reflexes, or “C-start reflexes,” are a key…
Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade [Biophysics and Computational Biology]
1dArrestins were initially identified for their role in homologous desensitization and internalization of G protein–coupled receptors. Receptor-bound arrestins also initiate signaling by interacting with other signaling proteins. Arrestins scaffold MAPK signaling cascades, MAPK kinase kinase (MAP3K), MAPK kinase (MAP2K), and MAPK. In particular, arrestins facilitate ERK1/2 activation by scaffolding
Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses [Microbiology]
1dArthritogenic alphaviruses are globally distributed, mosquito-transmitted viruses that cause rheumatological disease in humans and include Chikungunya virus (CHIKV), Mayaro virus (MAYV), and others. Although serological evidence suggests that some antibody-mediated heterologous immunity may be afforded by alphavirus infection, the extent to which broadly neutralizing antibodies that protect agains
Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself [Immunology and Inflammation]
1dAdaptive immune recognition is mediated by the binding of peptide–human leukocyte antigen complexes by T cells. Positive selection of T cells in the thymus is a fundamental step in the generation of a responding T cell repertoire: only those T cells survive that recognize human peptides presented on the surface…
CREBA and CREBB in two identified neurons gate long-term memory formation in Drosophila [Neuroscience]
1dEpisodic events are frequently consolidated into labile memory but are not necessarily transferred to persistent long-term memory (LTM). Regulatory mechanisms leading to LTM formation are poorly understood, however, especially at the resolution of identified neurons. Here, we demonstrate enhanced LTM following aversive olfactory conditioning in Drosophila when the transcription factor…
Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain [Psychological and Cognitive Sciences]
1dThe origins of oscillatory activity in the brain are currently debated, but common to many hypotheses is the notion that they reflect interactions between brain areas. Here, we examine this possibility by manipulating the strength of coupling between two human brain regions, ventral premotor cortex (PMv) and primary motor cortex…
Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division [Cell Biology]
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1dCar Cell Tumor Cancer
The formation of the branched actin networks is essential for cell polarity, but it remains unclear how the debranching activity of actin filaments contributes to this process. Here, we showed that an evolutionarily conserved coronin family protein, the Caenorhabditis elegans POD-1, debranched the Arp2/3-nucleated actin filaments in vitro. By fluorescence…
Secure human attachment can promote support for climate change mitigation [Sustainability Science]
1dAttachment theory is an ethological approach to the development of durable, affective ties between humans. We propose that secure attachment is crucial for understanding climate change mitigation, because the latter is inherently a communal phenomenon resulting from joint action and requiring collective behavioral change. Here, we show that priming attachment…
Cancer-associated mutations in the p85{alpha} N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases [Cell Biology]
1dThe phosphoinositide 3-kinase regulatory subunit p85α is a key regulator of kinase signaling and is frequently mutated in cancers. In the present study, we showed that in addition to weakening the inhibitory interaction between p85α and p110α, a group of driver mutations in the p85α N-terminal SH2 domain activated EGFR,…
NMDARs in granule cells contribute to parallel fiber-Purkinȷe cell synaptic plasticity and motor learning [Neuroscience]
1dLong-term synaptic plasticity is believed to be the cellular substrate of learning and memory. Synaptic plasticity rules are defined by the specific complement of receptors at the synapse and the associated downstream signaling mechanisms. In young rodents, at the cerebellar synapse between granule cells (GC) and Purkinje cells (PC), bidirectional…
Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates [Applied Physical Sciences]
1dMembraneless compartments, also known as condensates, provide chemically distinct environments and thus spatially organize the cell. A well-studied example of condensates is P granules in the roundworm Caenorhabditis elegans that play an important role in the development of the germline. P granules are RNA-rich protein condensates that share the key…
Growth-defense trade-offs shape population genetic composition in an iconic forest tree species [Ecology]
1dAll organisms experience fundamental conflicts between divergent metabolic processes. In plants, a pivotal conflict occurs between allocation to growth, which accelerates resource acquisition, and to defense, which protects existing tissue against herbivory. Trade-offs between growth and defense traits are not universally observed, and a central prediction of plant evolutionary ecology…
IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+ through the noncanonical STAT3 pathway [Immunology and Inflammation]
1dInterleukin 6 (IL-6) is known to regulate the CD4 T cell function by inducing gene expression of a number of cytokines through activation of Stat3 transcription factor. Here, we reveal that IL-6 strengthens the mechanics of CD4 T cells. The presence of IL-6 during activation of mouse and human CD4…
Optimal ligand discrimination by asymmetric dimerization and turnover of interferon receptors [Biophysics and Computational Biology]
1dIn multicellular organisms, antiviral defense mechanisms evoke a reliable collective immune response despite the noisy nature of biochemical communication between tissue cells. A molecular hub of this response, the interferon I receptor (IFNAR), discriminates between ligand types by their affinity regardless of concentration. To understand how ligand type can be…
Rational design of ASCT2 inhibitors using an integrated experimental-computational approach [Biophysics and Computational Biology]
1dASCT2 (SLC1A5) is a sodium-dependent neutral amino acid transporter that controls amino acid homeostasis in peripheral tissues. In cancer, ASCT2 is up-regulated where it modulates intracellular glutamine levels, fueling cell proliferation. Nutrient deprivation via ASCT2 inhibition provides a potential strategy for cancer therapy. Here, we rationally designed stereospecific inhibitors exploiting…
The global effectiveness of fact-checking: Evidence from simultaneous experiments in Argentina, Nigeria, South Africa, and the United Kingdom [Social Sciences]
1dThe spread of misinformation is a global phenomenon, with implications for elections, state-sanctioned violence, and health outcomes. Yet, even though scholars have investigated the capacity of fact-checking to reduce belief in misinformation, little evidence exists on the global effectiveness of this approach. We describe fact-checking experiments conducted simultaneously in Argentina,…
Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons [Immunology and Inflammation]
1dLate-stage anthrax infections are characterized by dysregulated immune responses and hematogenous spread of Bacillus anthracis, leading to extreme bacteremia, sepsis, multiple organ failure, and, ultimately, death. Despite the bacterium being nonhemolytic, some fulminant anthrax patients develop a secondary atypical hemolytic uremic syndrome (aHUS) through unknown mechanisms. We recapitulated the
Diphthamide promotes TOR signaling by increasing the translation of proteins in the TORC1 pathway [Biochemistry]
1dDiphthamide, a modification found only on translation elongation factor 2 (EF2), was proposed to suppress −1 frameshifting in translation. Although diphthamide is conserved among all eukaryotes, exactly what proteins are affected by diphthamide deletion is not clear in cells. Through genome-wide profiling for a potential −1 frameshifting site, we identified…
MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells [Cell Biology]
1dMultiple placental pathologies are associated with failures in trophoblast differentiation, yet the underlying transcriptional regulation is poorly understood. Here, we discovered msh homeobox 2 (MSX2) as a key transcriptional regulator of trophoblast identity using the human trophoblast stem cell model. Depletion of MSX2 resulted in activation of the syncytiotrophoblast transcriptional…
Norms of assertion in the United States, Germany, and Japan [Psychological and Cognitive Sciences]
1dThe recent controversy about misinformation has moved a question into the focus of the public eye that has occupied philosophers for decades: Under what conditions is it appropriate to assert a certain claim? When asserting a claim that x, must one know that x? Must x be true? Might it…
All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity [Neuroscience]
1dDisinhibition is an obligatory initial step in the remodeling of cortical circuits by sensory experience. Our investigation on disinhibitory mechanisms in the classical model of ocular dominance plasticity uncovered an unexpected form of experience-dependent circuit plasticity. In the layer 2/3 of mouse visual cortex, monocular deprivation triggers a complete, “all-or-none,”…
Discovery of complex oxides via automated experiments and data science [Chemistry]
1dThe quest to identify materials with tailored properties is increasingly expanding into high-order composition spaces, with a corresponding combinatorial explosion in the number of candidate materials. A key challenge is to discover regions in composition space where materials have novel properties. Traditional predictive models for material properties are not accurate…
One-dimensional van der Waals heterostructures: Growth mechanism and handedness correlation revealed by nondestructive TEM [Applied Physical Sciences]
1dWe recently synthesized one-dimensional (1D) van der Waals heterostructures in which different atomic layers (e.g., boron nitride or molybdenum disulfide) seamlessly wrap around a single-walled carbon nanotube (SWCNT) and form a coaxial, crystalized heteronanotube. The growth process of 1D heterostructure is unconventional—different crystals need to nucleate on a highly curved…
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs [Physiology]
1dβ cells produce, store, and secrete insulin upon elevated blood glucose levels. Insulin secretion is a highly regulated process. The probability for insulin secretory granules to undergo fusion with the plasma membrane or being degraded is correlated with their age. However, the molecular features and stimuli connected to this behavior…
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics [Medical Sciences]
1dMacromolecules such as monoclonal antibodies (mAbs) are likely to experience poor tumor penetration because of their large size, and thus low drug exposure of target cells within a tumor could contribute to suboptimal responses. Given the challenge of inadequate quantitative tools to assess mAb activity within tumors, we hypothesized that…
Regulation of P2X1 receptors by modulators of the cAMP effectors PKA and EPAC [Cell Biology]
1dP2X1 receptors are adenosine triphosphate (ATP)-gated cation channels that are functionally important for male fertility, bladder contraction, and platelet aggregation. The activity of P2X1 receptors is modulated by lipids and intracellular messengers such as cAMP, which can stimulate protein kinase A (PKA). Exchange protein activated by cAMP (EPAC) is another…
COVID-19 and mental health of individuals with different personalities [Economic Sciences]
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1dCovid Mental Health
Several studies have been devoted to establishing the effects of the COVID-19 pandemic on mental health across gender, age, and ethnicity. However, much less attention has been paid to the differential effect of COVID-19 according to different personalities. We do this using the UK Household Longitudinal Study (UKHLS), a large-scale…
Two-step deswelling in the Volume Phase Transition of thermoresponsive microgels [Applied Physical Sciences]
1dThermoresponsive microgels are one of the most investigated types of soft colloids, thanks to their ability to undergo a Volume Phase Transition (VPT) close to ambient temperature. However, this fundamental phenomenon still lacks a detailed microscopic understanding, particularly regarding the presence and the role of charges in the deswelling process….
Monolayer graphene membranes for molecular separation in high-temperature harsh organic solvents [Engineering]
1dThe excellent thermal and chemical stability of monolayer graphene makes it an ideal material for separations at high temperatures and in harsh organic solvents. Here, based on understanding of solvent permeation through nanoporous graphene via molecular dynamics simulation, a resistance model was established to guide the design of a defect-tolerant…
The 50th anniversary of the Konopka and Benzer 1971 paper in PNAS: “Clock Mutants of Drosophila melanogaster” [Genetics]
1dOn September 1, 1971, unknowingly to most, the world changed for the fields of behavioral genetics and circadian clocks. Ronald Konopka, a graduate student with Seymour Benzer at Caltech, published a paper (1) that I would argue is the most important discovery ultimately leading to our current molecular understanding of…
World’s biggest plant to suck carbon dioxide from the air goes into operation in Iceland
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How blockchain could help integrate rooftop solar and EVs into the grid: Australia is testing the tech behind Bitcoin to solve the grid's thorniest challenges using the power of distributed energy.
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Researchers from the Harvard’s Wyss Institute for Biologically Inspired Engineering have created a new gene-editing tool that can enable scientists to perform millions of genetic experiments simultaneously.
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Australian researchers have developed an exotic DNA-based detector that could help spot dark matter and the direction in space it comes from
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A NASA funded startup called Astrobotic wants to deliver payloads to the lunar surface twice a year
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