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KORTERE ARBEJDSUGE GIVER FORDELE: Experiment in Iceland shows promising results for shorter work weeks. People from different work sectors participated in the experiment and not only the efficacy of their work improved, but also the quality of their personal lives. This could mean a change in work hours in future for everyone.
Most biological traits are inherited via genes, but there are exceptions to this rule. Two teams from the University of Geneva (UNIGE) have been investigating the location of centromeres—specific sites on chromosomes that are essential for cell division. They found that in the small worm Caenorhabiditis elegans, the transmission of the correct location of these sites to the offspring is not mediat
Close contacts of people in England who test positive will not have to self-isolate if they have had both vaccinations Coronavirus – latest updates See all our coronavirus coverage Close contacts of people in England who have tested positive for Covid will not have to self-isolate if they have received both their vaccinations, or if they are under 18, Sajid Javid has announced to the Commons. The
Long Weekend After an experimental drop to a four-day work week in Iceland, workers were both more productive and satisfied with their jobs and lives. The experiment, which included more than 2,500 Icelandic workers from a variety of public-sector industries including healthcare and education, supported the idea that paying people the same amount of money for less work resulted in widespread bene
A team of researchers in China has claimed a new record in quantum computing, saying its new computer is far more powerful than any that came before it — including the best effort by the megacorporation Google. In a preprint uploaded to arXiv , the researchers claim their quantum computer was able to solve a problem using 56 out of its 66 qubits, the quantum equivalent of bits in a conventional c
Most of us are familiar with the fact that women live longer than men. But fellas, if we told you there was one thing that could be done to increase your lifespan, would you do it?
A unique study of ancient diamonds has shown that the basic chemical composition of the Earth's atmosphere which makes it suitable for life's explosion of diversity was laid down at least 2.7 billion years ago. Volatile gases conserved in diamonds found in ancient rocks were present in similar proportions to those found in today's mantle, which in turn indicates that there has been no fundamental
A combined team of researchers from ETH Zurich, Institute for Atmospheric and Climate Science and Newcastle University, has found via statistical analysis and modeling that rainfall in Europe could be increased by planting more trees. In their paper published in the journal Nature Geoscience, the group describes using data from rain gauges across Europe to build their models. Jessica Baker with th
A measurement of a fundamental principle of the standard model of particle physics—lepton flavour universality—captured by the ATLAS detector at the Large Hadron Collider, is reported in a paper published in Nature Physics.
A massive volcanic eruption in Indonesia about 74,000 years ago likely caused severe climate disruption in many areas of the globe, but early human populations were sheltered from the worst effects, suggests a new study published in the journal PNAS.
The surprising results of a decade-long investigation by Alessandro Vezzosi and Agnese Sabato provide a strong basis for advancing a project researching Leonardo da Vinci's DNA.
Kevo in Lapland recorded a temperature of 33.6C after Finland registered record heat in June Nordic countries have registered near-record temperatures over the weekend, including highs of 34C (93.2F) in some places. The latest figures came after Finland’s national meteorological institute registered its hottest temperature for June since records began in 1844. Continue reading…
Getting Knowledge A 11-year-old boy from Belgium just graduated from the University of Antwerp with a bachelor’s degree in physics, local newspaper De Telegraaf reports — and with the highest distinction. “I don’t really care if I’m the youngest,” Laurent Simons told the newspaper, as translated by Newsweek . “It’s all about getting knowledge for me.” It’s an astonishing achievement — and in an e
A retired gas-fired power plant was converted into a Bitcoin-mining facility in the Finger Lakes region of New York state — and NBC reports that neighbors say it’s pumping serious amounts of heat into the lake’s waters. “The lake is so warm you feel like you’re in a hot tub,” Abi Buddington, who loves close to the plant, told the outlet. The plant is taking in and pumping out over 100 million gal
Ridin’ Solo A team of scientists managed to spot an entire population of freely-floating, Earth-sized exoplanets that are sailing through space rather than orbiting a star. By spotting the tiny fluctuations in a star’s light when a planet passes in front of it — called a microlensing event because the planet’s gravity lightly warps the star’s light — researchers were able to spot dozens of free-f
Americans aren’t making as many babies as they used to. Last year, 3.6 million were born—the lowest count since 1979. The pandemic “baby bust” could push 2021’s tally down even further; researchers have estimated that the coronavirus and its economic impact could lead to about 300,000 fewer births in the United States this year. News of declining birth rates is not always a bad thing. It can mean
To visit Mitch McConnell at his office in the Capitol, you must first pass through a faded world that he has meticulously preserved. A fireplace in the reception room still bears a crack left by a fire British soldiers set during the War of 1812. Through a doorway, a conference room displays portraits of former GOP Senate leaders, among them the luckless Charles McNary, who landed the job just wh
The PM says he will keep his covering in crowded places after England’s rules change but what do his ministers and experts think? Coronavirus – latest updates See all our coronavirus coverage Boris Johnson has said he will continue to wear a mask in “crowded places” after mandatory requirements are dropped in England on 19 July. “What we’re trying to do is move from a universal government diktat
The company faces declining sales and thousands of lawsuits claiming it knowingly sold its trendy vaping products to minors. Soon the F.D.A. will decide whether it can keep selling them at all.
During his doctoral research on the ties between aging and mitochondria, Martin Picard frequently saw micrographs of those energy-producing organelles. Yet it wasn’t until fairly late in his graduate work that he first watched sped-up video of mitochondria moving inside live human cells, and the sight came as a revelation. Tagged with fluorescent dye, the mitochondria were neon squiggles crawling
“W e have destroyed the myth that Fidesz is unbeatable,” Gergely Karácsony said after defeating Viktor Orbán’s party in Budapest’s mayoral race in 2019. Now, he hopes to prove it at the national level too. After 12 years, Orbán claims near-complete control over Hungary’s public funds, its institutions, and its media ecosystem. Hungarian elections are “free in the sense that no one stuffs the ball
Chomp L ‘oeil Earth’s orbit is becoming increasingly littered with our leftover garbage. More than 27,000 pieces of orbital debris of varying sizes are being tracked by the Department of Defense’s global Space Surveillance Network. That could make launching rockets increasingly difficult in the future, let alone the danger space debris poses to space travelers. But in a Saturday tweet , SpaceX CE
Last month, a mysterious man shocked New Yorkers and the world as he soared over Times Square on what appeared to be a giant drone — something approaching a real-life hoverboard, and which drew immediate comparison to the fictional Spider-Man villain, the Green Goblin. The man was Hunter Kowald, and he says the drone-like vehicle is his own design and creation that he calls the SkySurfer. Kowald’
Police in India recently broke up a massive ring of scammers who injected thousands of people with fake COVID-19 vaccines — and collected the profits from the worthless shots. The scammers injected about 2,500 victims with salt water instead of the coronavirus vaccines they promised, making off with about $28,000, CNN reports . The scammers ran over a dozen fake vaccination sites in and around Mu
Shocked-Pikachu.png After Tesla once again delayed the launch of its next “Full Self-Driving” (FSD) software beta, Elon Musk admitted that he’s been caught off guard by just how difficult it is to develop autonomous vehicles. The upcoming beta of FSD 9 won’t actually make a Tesla fully autonomous no matter what the name implies, Insider notes . But whenever it does come out, the beta will still b
When we masked and stayed home, we were shielded from winter viruses. As we get back to normal, some will resurge—and our immune systems may not be prepared.
The best astronomy photos of the year invite the eye upward and outward, bringing stunning views such as auroras above Earth and visions of a stellar nursery 554 light-years away.
Eras of music are commonly defined by particular sounds. The ’80s had gated reverb , the aughts had Timbaland’s beats, and the early 2020s have had the froggy, rasping splendor of Doja Cat’s voice. On a slew of recent hits and on her new, third album, Planet Her , the 25-year-old rapper and singer continues to prove she has an extremely now sensibility: steeped in online humor, thrilled by physic
Scientists have used data from the Southwest Research Institute-led Magnetospheric Multiscale (MMS) mission to explain the presence of energetic heavy elements in galactic cosmic rays (GCRs). GCRs are composed of fast-moving energetic particles, mostly hydrogen ions called protons, the lightest and most abundant elements in the universe. Scientists have long debated how trace amounts of heavy ions
As the old adage goes, you must spend money to make money. Just about anywhere, setting up shop requires a significant bit of cash. But as this world map shows, the cost varies greatly by country. Starting a business in the U.S. costs $735, which is relatively affordable at just 16 percent of the average monthly paycheck. Credit : Jason Kempin/Getty Images for iHeart Media Starting your own busin
Black holes can be perplexing and counterintuitive because they exist at the very edge of our current understanding of physics. Even as they’re warping the fabric of the universe, black holes have to obey certain rules. For the first time, we have direct confirmation of a vitally important property of these dead stars. Researchers from MIT and other institutions have confirmed Stephen Hawking’s b
As the rats ran down a short balance beam, stopping occasionally to poke their noses at a water fountain, their brains knew something was off. Inside the hippocampus, a brain region that documents the stories of your life, neurons sparked a strange type of electrical wave that washed over the region, altering its normal rhythm. You see, the rats were running in virtual reality (VR), one so rich a
It takes us less than half a second, on average, to decide whether a food tastes good but twice as long to decide how healthy it is, according to new research from LSE's Department of Management.
The Supreme Court has changed college admissions forever. The justices’ decision late last month allowing NCAA Division I football and men’s basketball programs to provide new educational incentives to student athletes created an overdue avenue for compensating student athletes in commercially lucrative sports, many of whom come from low-income backgrounds. And new rules the NCAA rolled out last
Astronomers from the University of Bonn, Germany and elsewhere have used the eROSITA telescope onboard the Spektrum-Roentgen-Gamma (SRG) mission to perform X-rays observations of a nearby galaxy cluster known as Abell 3158. Results of this observational campaign, published June 28 on arXiv.org, offer more clues on the properties of this giant structure.
One of the underreported tragedies of our time is that nearly 90% of the world's blind live in low-income countries where poverty and blindness perpetuate in a descending cycle. The main cause of this often needless and frequently avoidable blindness is cataracts , which affect 95 million people worldwide. In low- and middle-income countries cataracts account for 50% of all blindness , compared t
Two model studies document the probability of climate tipping in Earth subsystems. The findings support the urgency of restricting CO2 emissions as abrupt climate changes might be less predictable and more widespread in the climate system than anticipated. The work is part of the European TiPES project, coordinated by the University of Copenhagen, Denmark but was conducted by Professor Michael Ghi
Chemical elements make up pretty much everything in the physical world. As of 2016, we know of 118 elements, all of which can be found categorized in the famous periodic table that hangs in every chemistry lab and classroom.
On June 20, about 20,000 fans gathered at Madison Square Garden in New York City for a Foo Fighters concert. The venue was at full capacity for the first time since the start of the pandemic, but it wasn’t a full return to normalcy: To get in, ticket holders needed to show proof that they’d been vaccinated—in the form of either a paper card or the state’s Excelsior Pass, a much-debated smartphone
On the fourth of July, the US Food and Drug Administration (FDA) approved a new weight loss drug called semaglutide that doctors say could be a huge improvement in treatment for overweight patients. The drug, which is being marketed as Wegovy by Novo Nordisk, is actually the synthetic version of a hormone found in a Gila monster’s deadly venom, according to Vox . In one clinical trial, the averag
American universities often use semester calendars, but many still use the quarter system. Students at schools that switched to semesters from quarters got lower grades and took longer to graduate. The higher number of concurrent classes may be the cause of students' woes. An academic debate — "Are semesters or quarters better for college students?" — may finally have a definitive answer. A new s
Chronic pain affects about 40% of the UK population. While there is growing recognition that pain can be an illness in and of itself, there is still a lot we don’t know. Anand Jagatia hears from fibromyalgia sufferer Vicky Naylor on what it’s like to live with chronic pain, and the Guardian’s science correspondent Linda Geddes about the causes for these sometimes debilitating conditions Continue
Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.
The drive for more women and greater diversity in the space sector will lead to new ideas and innovations, from spacesuits to toilets and beyond “Remember when Nasa sent a woman to space for only six days and they gave her 100 tampons and asked will that be enough?” So goes last year’s viral TikTok referring to astronaut Sally Ride being asked by Nasa engineers in 1983 whether 100 tampons would b
The sun emitted a significant solar flare peaking at 10:29 a.m. EDT on July 3, 2021. NASA's Solar Dynamics Observatory, which watches the sun constantly, captured an image of the event.
Emitted as gases from certain solids or liquids, volatile organic compounds (VOCs) include a variety of chemicals. Many of these chemicals are associated with a range of adverse human health effects, from eye, nose, and throat irritation, to liver, kidney, and central nervous system damage.
Whether in smartphones, televisions or building technology, semiconductors play a central role in electronics and therefore in our everyday lives. In contrast to metals, it is possible to adjust their electrical conductivity by applying a voltage and hence to switch the current flow on and off.
A new nanotechnology development by an international research team led by Tel Aviv University researchers will make it possible to generate electric currents and voltage within the human body through the activation of various organs (mechanical force). The researchers explain that the development involves a new and very strong biological material, similar to collagen, which is non-toxic and causes
Researchers including a Keele University scientist have engineered an innovative approach to disable highly powerful genetic devices that control harmful insect populations.
In October 2019, I set sail with a team of scientists aboard the Canadian Coast Guard Vessel John P. Tully in the northeast Pacific Ocean, off the coast of Vancouver Island. Battling rough seas and lack of sleep, we spent the better part of a week working shoulder-to-shoulder in a small stand-up refrigerator, analyzing seafloor sediments to learn more about the effects of low-oxygen conditions on
In defining periods of development, the brain re-organizes connections between its neurons more freely than in its adult form. Researchers have now discovered two methods to reopen such plasticity: repeated ketamine anesthesia and non-invasive 60 hertz light flickering. The findings may have the potential to become a therapeutic tool applicable to humans.
Using artificial intelligence, UT Southwestern scientists have identified thousands of genetic mutations likely to affect the immune system in mice. The work is part of one Nobel laureate's quest to find virtually all such variations in mammals.
A study published in Nature Astronomy concludes that known geochemical processes can't explain the levels of methane measured by the Cassini spacecraft on Saturn's icy moon. While the paper by no means suggests that life exists on Enceladus, the results would be consistent with microbial activity similar to that known to occur at hydrothermal vents in Earth's oceans.
Using sophisticated simulations of the whole of the Local Group of galaxies, including the Milky Way, the Andromeda galaxy and their respective satellite galaxies, researchers have shown that the satellites not only can retain their gas but can also experience many new episodes of star formation just after passing close to the pericenter of their parent galaxy.
Researchers have discovered that two proteins, which are involved in the control of stem cells' division in plant roots, need each other for these cells to function properly. The study combines experimental work with plants and mathematical modeling. The mechanism provides knowledge that could be useful, for agriculture and for the design of efficient strategies in medicine and cosmetics that slow
More people than ever are suffering from things like anxiety, depression, and insomnia. Researchers started seeing the trend among millennials in the mid 2010s , citing things like student loan debt, the economy, and social media as possible causes. And things have only gotten worse during the pandemic. The good news is that, over the last decade, there has been a huge shift in the way people per
Autopilot Crash A fatal crash involving a Tesla Model 3 with Autopilot turned on is raising questions about the safety of the car company’s self-driving feature, The New York Times reports . In August 2019, 15-year-old Jovani Maldonado died after being thrown from his family’s Ford Explorer — he was reportedly not wearing a seatbelt — after being a collision with a Tesla Model 3, which was travel
A study led by University of Barcelona researchers and carried out together with more than 1,650 students and their family members from 18 educational centers in Barcelona shows that citizen science is a valid approach able for doing high quality science, and in this case, able to provide nitrogen dioxide values with an unprecedented resolution and to assess the impact of the pollution in the heal
People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. For those few vaccinated people who do still get an infection, or "breakthrough" cases, the study suggests that vaccines reduce the severity of COVID-19 symptoms and shorten its duration.
Researchers at the University of Massachusetts Amherst recently discovered that the ability of agricultural grasses to withstand drought is directly related to the health of the microbial community living on their stems, leaves and seeds.
Chromosomal instability is a feature of solid tumors such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular aging and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.
Five Simon Fraser University scholars are among international scientists sounding an alarm over the "pervasive social and ecological consequences" of the destruction and suppression of the knowledge systems of Indigenous Peoples and local communities.
By analyzing the genomes of 99 species of vinegar flies and evaluating their chemical odor profiles and sexual behaviors, researchers at the Max Planck Institute for Chemical Ecology show that sex pheromones and the corresponding olfactory channels in the insect brain evolve rapidly and independently. Female flies are able to recognize conspecific males through their specific odor profiles. Intere
Veterinarians at the University of California, Davis, have found that a cat's DNA alters how it responds to a life-saving medication used to treat hypertrophic cardiomyopathy, or HCM, a heart disease that affects 1 in 7 cats. The study was published in the journal Scientific Reports.
Many standard economic models assume people make perfectly rational, individual decisions. But new research suggests economic phenomena like inequality and business cycles are better explained by models which recognize that people's decisions are affected by the decisions and the behaviors of people around them.
Researchers have equipped an ultrathin semiconductor with superconducting contacts. These extremely thin materials with novel electronic and optical properties could pave the way for previously unimagined applications. Combined with superconductors, they are expected to give rise to new quantum phenomena and find use in quantum technology.
Researchers have developed an innovative material that is eco-friendly, completely biological and non-toxic, and causes no harm to the body's tissues. The material is as strong as titanium and extremely flexible. The new development will allow for the charging of pacemakers using only the heartbeat, eliminating the need for batteries. The new material will make it possible to produce green energy
Lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells. Cancer cells have a unique ability to metabolize substances differently from normal cells, and this ability is considered to be a promising therapeutic target. New findings may contribute to the safe and effective use of LSD1 inhibit
The Society for Academic Emergency Medicine (SAEM) is pleased to announce the release of the first publication in a series of Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE), which focuses on low-risk chest pain.
A new national study published in Psychiatric Services finds that over a quarter of US adults with depression or anxiety symptoms reported needing mental health counseling but were not able to access it during the COVID-19 pandemic. Researchers analyzed data from nearly 70,000 adults surveyed in the US Census Household Pulse Survey in December 2020.
Historically most scientists thought that once a satellite galaxy has passed close by its higher mass parent galaxy, its star formation would stop because the larger galaxy would remove the gas from it, leaving it shorn of the material it would need to make new stars. However, for the first time, a team led by Arianna di Cintio, a researcher at the Instituto de Astrofísica de Canarias (IAC), has s
The onset of the Indian summer monsoon has been predicted three months ahead for the last 40 years with the highest precision up until today. The result indicates longer seasonal forecasts based on machine learning may be a way to mitigate the consequences of an erratic monsoon system under future global warming. Dr. Takahito Mitsui and Dr. Niklas Boers of the Potsdam Institute of Climate Impact R
Amid calls for racial and social justice nationwide, businesses and educational institutions are grappling with how to adopt more inclusive organizational practices, including more diversified hiring. However, recruitment teams and strategic leaders often blame their lack of a diverse workforce on a lack of diverse applicants. A large study of recruitment data suggests a simple and efficient way o
How the media frame stories about science affects the public's perception about scientific accuracy and reliability, and one particular type of narrative can help ameliorate the harm to science's reputation sometimes caused by different journalistic approaches to scientific storytelling, according to a new study led by a University at Buffalo researcher.
A new study has found that the key properties of the spikes of SARS-CoV-2 virus which causes COVID-19 are consistent with those of several laboratory-developed protein spikes, designed to mimic the infectious virus. The findings show how that viral spike manufactured through different methods in laboratories across the globe are highly similar and provide reassurance that the spike can be robustly
How the media frame stories about science affects the public's perception about scientific accuracy and reliability, and one particular type of narrative can help ameliorate the harm to science's reputation sometimes caused by different journalistic approaches to scientific storytelling, according to a new study led by a University at Buffalo researcher.
Wangjinzhuang village is nestled amongst the steep slopes of the South Taihang Mountains in Hebei Province, China. To prosper in the northern climate, the villagers have developed a tried-and-true strategy: Using the land to plant a hundred kinds of crops and not rely on the sky. Their fields contain red millet, white sorghum, purple and green eyebrow beans, and yellow radishes. Having survived fo
Climate change is causing increased flooding and prolonged waterlogging in northern Europe, but also in many other parts of the world. This can damage meadow grasses, field crops or other plants—their leaves die, the roots rot.
The future of cod stocks in the North Sea and the Barents Sea may be much easier to predict than before. This is the result of an international research project led by the Helmholtz-Zentrum Hereon and its Institute of Coastal Systems—Analysis and Modeling. For the first time, the team has succeeded in predicting the development of stocks for ten years in advance, taking into account both changes d
Life history traits explain the vulnerability of endemic forest birds and predict recovery after predator suppression. New modeling, published in the New Zealand Journal of Ecology, has disentangled the limiting effects of predation, forest area, and food availability to predict the outcomes we can expect for different native bird species in a predator-free New Zealand.
One of the organisms attacked by the fungus Cyclocybe parasitica is the Tawa tree (Beilschmiedia tawa), which is relevant to the timber industry in New Zealand. Cyclocybe parasitica is widespread in the Pacific region and has long been known to the Maori, the indigenous people of New Zealand, under the name Tawaka as an edible wild mushroom.
Scientists at the University of Leeds have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins.
Many researchers in the field of materials science constantly seek novel and versatile platforms that can be used to tailor materials to match their intended use. One example of this are covalent organic frameworks (COFs), an emerging class of crystalline porous polymers with a favorable set of fundamental properties, namely crystallinity, stability, and porosity. This combination makes them, in t
The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors. Mitochondria, the power plants of cells, play a role in this programmed cell death. Scientists from the University of Groningen (the Netherlands) and the University of Pittsburgh (U.S.) have obtained new insights in how mitochondria receive the signal to self-de
What if the COVID-19 virus could be used against itself? Researchers at Penn State have designed a proof-of-concept therapeutic that may be able to do just that. The team designed a synthetic defective SARS-CoV-2 virus that is innocuous but interferes with the real virus's growth, potentially causing the extinction of both the disease-causing virus and the synthetic virus.
Researchers analyze bone marrow-derived and peripheral blood-derived fibrin clots showing that the former contains more growth factors. They then show that bone marrow-derived fibrin clots can be used for meniscus suturing, even in the inner-most avascular regions, and with a 2-year post-operative follow-up, they show bone marrow-derived fibrin clots support healing better than their peripheral bl
Switchgrass, a native prairie species, is championed as a promising bioenergy crop due to its ability to grow across many climates. It is also known to associate with beneficial microbes. To better understand the relationship between switchgrass and soil microbes, researchers at Michigan State University and Washington State University examined soil microbial communities and root traits among 12 s
A study conducted at the University of São Paulo suggests that tissues specializing in saliva production and secretion serve as reservoirs for SARS-CoV-2, magnifying its infectious potential.
Higher levels of plaque in people with HIV can be partly traced to the nontraditional risk factors of increased arterial inflammation and immune system activation. Researchers uncovered two key biomarkers of plaque that will be studied in the next phase of the global REPRIEVE trial to predict coronary plaque progression and major cardiovascular events, such as heart attacks and stroke, and the pot
Cardiovascular drugs do not affect COVID-19 outcomes–such as disease severity, hospitalizations, or deaths–according to an analysis of all relevant studies published as of November 2020. The findings are published in the British Journal of Clinical Pharmacology.
Yesterday, the oil-producers cartel OPEC—which is now somewhat cheekily called “OPEC+,” because Russia joined in 2016—failed to reach an agreement on increasing oil production. Stick with me for a second, because this may not seem like it has much to do with climate change, but in fact it reveals how decarbonization is already shifting how money is spent and how geopolitical power is exercised. I
Researchers at Linköping University have developed a method that may lead to new types of displays based on structural colors. The discovery opens the way to cheap and energy-efficient color displays and electronic labels. The study has been published in the scientific journal Advanced Materials.
Increased labor mobility seems to have stopped the racial wage discrimination of Black English football players. A new study in economics from Stockholm university and Université Paris-Saclay used data from the English Premier League to investigate the impact of the so-called "Bosman ruling," and found that racial discrimination against English football players disappeared—but not for non-EU playe
City sprawl and road development is increasingly fragmenting the habitats that many plant and animal species need to survive. Ecologists have long known than sustainable development requires attention to ecological connectivity—the ability to keep plant and wildlife populations intact and healthy, typically by preserving large tracts of land or creating habitat corridors for animals. New research
Researchers have shown how worms learn to optimize their foraging activity by switching their response to pheromones in the environment, according to a report published today in eLife.
Researchers from Pompeu Fabra University (Barcelona, Spain) have analyzed the way citizen science is practiced in Spain. The paper, produced by Carolina Llorente and Gema Revuelta, from UPF's Science, Communication and Society Studies Centre (CCS-UPF) and Mar Carrió, from the University's Health Sciences Educational Research Group (GRECS), has been published in the Journal of Science Communication
The braincase of crocodylians has a distinctive structure. Unlike evolutionary relatives (birds and squamates), in crocodylians, all braincase bones are rigidly fixed together and form an akinetic structure. In the process of evolution, this made it possible for animals to develop powerful jaws and stronger bite forces, thanks to which crocodylians could gnaw through the hard shell of crayfish and
Many people who undergo trauma take a long time to truly heal from the post-traumatic stress disorder, which manifests as flashbacks and nightmares to the traumatic incident. Medical researchers have been trying different therapeutic approaches to reduce these manifestations. A group of Japanese medical researchers report that trihexyphenidyl, a central anticholinergic drug, might just be the answ
NYU Abu Dhabi (NYUAD) researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate. This finding offers new insight into how the specific genes that promote regeneration can be activated when part of the liver is removed. These findings have the potential to inform the development of a new form of regenerative medicine that could
For the first time, University of Basel researchers have equipped an ultrathin semiconductor with superconducting contacts. These extremely thin materials with novel electronic and optical properties could pave the way for previously unimagined applications. Combined with superconductors, they are expected to give rise to new quantum phenomena and find use in quantum technology.
Until now, fisheries have set catch levels a year in advance. Long-term influences such as changes in water temperatures are not taken into account. In an international project, researchers from Helmholtz-Zentrum Hereon have now developed a computational model that can estimate the future of cod a full ten years in advance – taking into both account fishing and climate. The fishing industry has a
Researchers from HSE University and Max Planck Institute for Human Cognitive and Brain Sciences have discovered how the theta rhythm of the brain and the gender differences in attitudes to risk are linked. In an article published in the journal Frontiers in Neuroscience, the researchers addressed which processes can be explained by knowing this connection.
Using simple blood tests could help researchers identify children who have been misidentified as having severe malaria, according to a study published today in eLife.
Although the history of bitumen dates back to the third millennium BC, only little is known about its surface structure. Researchers are now shedding light on the nature of the bitumen surface using physicochemical analyses.
Scientists have developed a new technique of predefining the crack pattern on a flexible substrate by a sequential deposition of metallic layers which leads to a formation of a zerogap between the adjacent lateral patterns.
Multiple research efforts are recording and analyzing the advanced clicks and unique vocalizations of whales in the ocean. The work could reveal similarities between human and cetacean behaviors.
A recent collaboration between scientists in Michigan and Massachusetts as well as South Korea resulted in the development of a novel and broadly applicable molecular assay that used a model fungus to investigate how plant fungal pathogens circumvent the bioactivity of SDHIs. Through this analysis, they were able to successfully validate known mechanisms of fungicide resistance in several agricult
A transplant of healthy gut microbes followed by fibre supplements benefits patients with severe obesity and metabolic syndrome, according to University of Alberta clinical trial findings published today in Nature Medicine.
A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).
A molecule extracted from European chestnut tree leaves has the power to neutralize dangerous, drug-resistant staph bacteria, a new study shows. Researchers dubbed the molecule Castaneroxy A, after the genus of the European chestnut, Castanea . The use of chestnut leaves in traditional folk remedies in rural Italy inspired the research. “We were able to isolate this molecule, new to science, that
The Toba eruption ∼74,000 y ago was the largest volcanic eruption since the start of the Pleistocene and represents an important test case for understanding the effects of large explosive eruptions on climate and ecosystems. However, the magnitude and repercussions of climatic changes driven by the eruption are strongly debated….
Preexploitation shark baselines and the history of human impact on coral reef–associated shark communities in the Caribbean are tpoorly understood. We recovered shark dermal denticles from mid-Holocene (∼7 ky ago) and modern reef sediments in Bocas del Toro, Caribbean Panama, to reconstruct an empirical shark baseline before major human impact…
With over 18,000 species, the Acanthomorpha, or spiny-rayed fishes, form the largest and arguably most diverse radiation of vertebrates. One of the key novelties that contributed to their evolutionary success are the spiny rays in their fins that serve as a defense mechanism. We investigated the patterning mechanisms underlying the…
Goldstein et al.’s (1) article, “Vaccinating the oldest against COVID-19…,” provides a useful and timely analysis of the value of protecting older people from infection. The authors show convincingly that the expected number of life years saved by focusing protection on old people is more than commonly supposed. Unfortunately, the…
Who should be vaccinated first against COVID-19? This complex question links science, policy, and ethics, and was recently tackled by Goldstein et al. (1) (henceforth GCW). GCW offer an advance that reduces the complexity of this issue by showing that, under certain conditions, vaccinating the oldest first maximizes both the…
In our PNAS brief report about COVID-19 vaccination priorities (1), we present a demographic analysis of characteristic age-specific schedules of COVID-19 death rates and show, contrary to widespread intuition, that the goals of maximizing lives saved per vaccination and of maximizing years of future life saved per vaccination are not…
Despite decades of policy that strives to reduce nutrient and sediment export from agricultural fields, surface water quality in intensively managed agricultural landscapes remains highly degraded. Recent analyses show that current conservation efforts are not sufficient to reverse widespread water degradation in Midwestern agricultural systems. Intensifying row crop agriculture and…
A fundamental issue in migration biology is how birds decide when to start their journey, given that arriving too early or too late in a variable environment reduces individual fitness. Internal circannual regulation and predictable cues such as photoperiod prepare birds for migration, while variable external cues such as temperature…
A significant unmet need for new contraceptive options for both women and men remains due to side-effect profiles, medical concerns, and the inconvenience of many currently available contraceptive products. Unfortunately, the development of novel nonsteroidal female contraceptive medicine has been stalled in the last couple of decades due to the…
Centrosome duplication and DNA replication are two pivotal events that higher eukaryotic cells use to initiate proliferation. While DNA replication is initiated through origin licensing, centrosome duplication starts with cartwheel assembly and is partly controlled by CP110. However, the upstream coordinator for both events has been, until now, a mystery….
Near-field hydrodynamic interactions in active fluids are essential to determine many important emergent behaviors observed, but have not been successfully modeled so far. In this work, we propose an effective model capturing the essence of the near-field hydrodynamic interactions through a tensorial coefficient of resistance, validated numerically by a pedagogic…
The evolutionary expansion of G protein-coupled receptors (GPCRs) has produced a rich diversity of transmembrane sensors for many physical and chemical signals. In humans alone, over 800 GPCRs detect stimuli such as light, hormones, and metabolites to guide cellular decision-making primarily using intracellular G protein signaling networks. This diversity is…
The contribution of NETs (neutrophil extracellular traps) to thrombus formation has been intensively documented in both arterial and venous thrombosis in mice. We previously demonstrated that adenosine triphosphate (ATP)–activated neutrophils play a key role in initiating the tissue factor–dependent activation of the coagulation cascade, leading to thrombus formation following laser-induced…
Electrostimulation has been recognized as a promising nonpharmacological treatment in orthopedics to promote bone fracture healing. However, clinical applications have been largely limited by the complexity of equipment operation and stimulation implementation. Here, we present a self-powered implantable and bioresorbable bone fracture electrostimulation device, which consists of a triboelectric n
Family planning programs are believed to have substantial long-term benefits for women’s health and well-being, yet few studies have established either extent or direction of long-term effects. The Matlab, Bangladesh, maternal and child health/family planning (MCH/FP) program afforded a 12-y period of well-documented differential access to services. We evaluate its…
Injection of effector proteins to block host innate immune signaling is a common strategy used by many pathogenic organisms to establish an infection. For example, pathogenic Yersinia species inject the acetyltransferase YopJ into target cells to inhibit NF-κB and MAPK signaling. To counteract this, detection of YopJ activity in myeloid…
Colonially breeding birds and mammals form some of the largest gatherings of apex predators in the natural world and have provided model systems for studying mechanisms of population regulation in animals. According to one influential hypothesis, intense competition for food among large numbers of spatially constrained foragers should result in…
Adaptation to different climates fuels the origins and maintenance of biodiversity. Detailing how organisms optimize fitness for their local climates is therefore an essential goal in biology. Although we increasingly understand how survival-related traits evolve as organisms adapt to climatic conditions, it is unclear whether organisms also optimize traits that…
Voltage-gated sodium (NaV) channels control excitable cell functions. While structural investigations have revealed conformation details of different functional states, the mechanisms of both activation and slow inactivation remain unclear. Here, we identify residue T140 in the S4–S5 linker of the bacterial voltage-gated sodium channel NaChBac as critical for channel activation…
Novel MRI techniques allow a noninvasive quantification of tissue sodium and reveal the skin as a prominent compartment of sodium storage in health and disease. Since multiple sclerosis (MS) immunopathology is initiated in the periphery and increased sodium concentrations induce proinflammatory immune cells, the skin represents a promising compartment linking…
During operations, surgical mesh is commonly fixed on tissues through fasteners such as sutures and staples. Attributes of surgical mesh include biocompatibility, flexibility, strength, and permeability, but sutures and staples may cause stress concentration and tissue damage. Here, we show that the functions of surgical mesh can be significantly broadened…
It is known that tumor growth can be influenced by the nervous system. It is not known, however, if tumors communicate directly with the central nervous system (CNS) or if such interactions may impact tumor growth. Here, we report that ventrolateral medulla (VLM) catecholaminergic (CA) neurons in the mouse brain…
Epitope III, a highly conserved amino acid motif of 524APTYSW529 on the hepatitis C virus (HCV) E2 glycoprotein, resides in the critical loop that binds to the host receptor CD81, thus making it one of the most important antibody targets for blocking HCV infections. Here, we have determined the X-ray…
Intraoperative delineation of tumor margins is critical for effective pancreatic cancer surgery. Yet, intraoperative frozen section analysis of tumor margins is a time-consuming and often challenging procedure that can yield confounding results due to histologic heterogeneity and tissue-processing artifacts. We have previously described the development of the MasSpec Pen technology…
Sinoatrial node myocytes (SAMs) act as cardiac pacemaker cells by firing spontaneous action potentials (APs) that initiate each heartbeat. The funny current (If) is critical for the generation of these spontaneous APs; however, its precise role during the pacemaking cycle remains unresolved. Here, we used the AP-clamp technique to quantify…
Understanding the potential of nanomaterials (NMs) to cross the blood–brain barrier (BBB), as a function of their physicochemical properties and subsequent behavior, fate, and adverse effect beyond that point, is vital for evaluating the neurological effects arising from their unintentional entry into the brain, which is yet to be fully…
Pseudomonas aeruginosa is an opportunistic pathogen that forms antibiotic-resistant biofilms, which facilitate chronic infections in immunocompromised hosts. We have previously shown that P. aeruginosa secretes outer-membrane vesicles that deliver a small RNA to human airway epithelial cells (AECs), in which it suppresses the innate immune response. Here, we demonstrate that…
The single most intrinsic property of nonrigid polymer chains is their ability to adopt enormous numbers of chain conformations, resulting in huge conformational entropy. When such macromolecules move in media with restrictive spatial constraints, their trajectories are subjected to reductions in their conformational entropy. The corresponding free energy landscapes are…
Forward genetic studies use meiotic mapping to adduce evidence that a particular mutation, normally induced by a germline mutagen, is causative of a particular phenotype. Particularly in small pedigrees, cosegregation of multiple mutations, occasional unawareness of mutations, and paucity of homozygotes may lead to erroneous declarations of cause and effect….
How noncoding transcription influences chromatin states is still unclear. The Arabidopsis floral repressor gene FLC is quantitatively regulated through an antisense-mediated chromatin silencing mechanism. The FLC antisense transcripts form a cotranscriptional R-loop that is dynamically resolved by RNA 3′ processing factors (FCA and FY), and this is linked to chromatin…
Opioid analgesics are efficacious painkillers for treating moderate to severe acute pain, but their long-term use in chronic pain has met with increasing scrutiny due to various on-target detrimental adverse effects, including the development of tolerance, physical or psychological dependence, constipation, and life-threatening respiratory arrest (1, 2). The “holy grail”…
I appreciate the recent comments by Zhuang et al. (1) on our report. The aim of our work (2) was to establish proof of concept that a positive allosteric modulator (PAM) of the mu-opioid receptor (MOR) affords antinociception in mice by amplifying the activity of opioid peptides acting at MOR….
In multicellular organisms, cell identity can be maintained through DNA methylation patterns that control gene expression (1). These and other epigenetic marks installed during development require erasure to facilitate zygote totipotency (2). Otherwise, epigenetic information may be transferred, at least transiently, across generations (1, 2). In mammals, epigenetic reprogramming during…
Soley (1) argues that our study (2) does not prove that “transgenerational [epigenetic] inheritance serv[es] an adaptive role in evolution” in honey bees. This view misrepresents our intent. Our main findings are that in honey bees 1) DNA methylation profiles are much more similar between fathers and daughters than between…
NEUROSCIENCE Correction for “Subregion-specific rules govern the distribution of neuronal immediate-early gene induction,” by Ben Jerry Gonzales, Diptendu Mukherjee, Reut Ashwal-Fluss, Yonatan Loewenstein, and Ami Citri, which was first published October 21, 2019; 10.1073/pnas.1913658116 (Proc. Natl. Acad. Sci. U.S.A. 117, 23304–23310). The authors note that: “The R analysis for panel…
Duchenne muscular dystrophy (DMD) is a devastating genetic disease leading to degeneration of skeletal muscles and premature death. How dystrophin absence leads to muscle wasting remains unclear. Here, we describe an optimized protocol to differentiate human induced pluripotent stem cells (iPSC) to a late myogenic stage. This allows us to…
Anthropogenic nutrient enrichment is driving global biodiversity decline and modifying ecosystem functions. Theory suggests that plant functional types that fix atmospheric nitrogen have a competitive advantage in nitrogen-poor soils, but lose this advantage with increasing nitrogen supply. By contrast, the addition of phosphorus, potassium, and other nutrients may benefit such…
Subglacial water flow strongly modulates glacier basal motion, which itself strongly influences the contributions of glaciers and ice sheets to sea level rise. However, our understanding of when and where subglacial water flow enhances or impedes glacier flow is limited due to the paucity of direct observations of subglacial drainage…
The transition from childhood to adolescence is marked by pronounced shifts in brain structure and function that coincide with the development of physical, cognitive, and social abilities. Prior work in adult populations has characterized the topographical organization of the cortex, revealing macroscale functional gradients that extend from unimodal (somatosensory/motor and…
Catastrophic decline of Indigenous populations in the Americas following European contact is one of the most severe demographic events in the history of humanity, but uncertainty persists about the timing and scale of the collapse, which has implications for not only Indigenous history but also the understanding of historical ecology….
University of California San Diego School of Medicine researchers identified a possible link between inadequate exposure to ultraviolet-B (UVB) light from the sun and an increased risk of colorectal cancer.
The report details regulatory variants found near a gene, which plays a crucial role joint formation called GDF5. The study pinpoints two separate mutations near the gene, one that can cause knee osteoarthritis in older adults and another that can cause hip dysplasia in babies.
A Duke University research team's deeper examination of the nutritional content of plant-based meat alternatives, using metabolomics, shows they're as different as plants and animals. Beef contained 22 metabolites that the plant substitute did not. The plant-based substitute contained 31 metabolites that meat did not. The greatest distinctions occurred in amino acids, dipeptides, vitamins, phenols
New research from the University of Massachusetts Amherst argues that it's not enough for ecological modelling to focus on the landscape. If we want the best-possible ecological management, we should consider when and where individuals are located.
Using an exceptionally preserved fossil from South Africa, a particle accelerator, and high-powered x-rays, an international team including a University of Minnesota researcher has discovered that not all dinosaurs breathed in the same way.
Necessity is the father of invention, but where is its mother? According to a new study published in Science, fewer women hold biomedical patents, leading to a reduced number of patented technologies designed to address problems affecting women.
Scientists have described two new species of palaeotheriidae mammals that inhabited the subtropical landscape of Zambrana (Álava) about 37 million years ago. Their atypical dental features could point to a difference in environmental conditions between the Iberian and Central European areas.
On Saturday, following heavy rains, a massive mudslide struck the seaside resort town of Atami, Japan, about 60 miles southwest of Tokyo, destroying more than 120 structures and killing at least seven people—with more than two dozen others still listed as missing. Search-and-rescue operations are underway, as workers and sniffer dogs slog through thick piles of mud and debris.
Researchers have found that changes in temperature and rainfall have lengthened allergy season in the Bay Area in California. Climate change has lengthened the local pollen and mold season by eight to nine weeks per year during the past two decades, according to a new study. The study, based on allergen data collected starting in 2002 in Los Altos Hills, California, found that local temperature i
As offices nationwide spring back to life, interior space designers and architects will soon have an easy-to-use planning tool to place indoor workplace furniture, staff, partitions and ventilation in a manner that maximizes fresh air flow and reduces the risk of airborne pathogens.
Findings from a study published today [6 July] in the Journal of the American Medical Association (JAMA) have prompted new World Health Organization (WHO) recommendations to use interleukin-6 antagonists in patients with severe or critical COVID-19 along with corticosteroids.
The health outcomes of preterm babies can be significantly improved by timely and appropriate interventions in women presenting with preterm labor. However, the non-specific nature of presenting signs and symptoms of preterm labor make it challenging to diagnose, and unnecessary overtreatment is both common and costly. A study published in PLOS Medicine by Sarah Stock at the University of Edinburg
A new modeling study suggests that significant variation in virus dynamics from person to person may be a contributing factor to inconsistent findings reported in clinical trials for antiviral COVID-19 drugs.
Clinical studies on drug candidates for COVID-19 may generate more robust results by ensuring randomization, early patient recruitment and treatment initiation, a new model shows.
A small fungal enzyme could play a significant role in simplifying the development and manufacturing of drugs, report scientists. The Rice University lab of chemical and biomolecular engineer Xue Sherry Gao and collaborators isolated a biocatalyst known as CtdE after identifying it as the natural mechanism that controls the chirality —the left- or right-handedness—of compounds that the native fun
With no examples of representative government across the Atlantic, the framers of the Constitution may have taken inspiration from the age-old traditions of the Haudenosaunee.
Amid a COVID surge in Africa, vaccine promises from richer nations are not enough to bring an early end to the pandemic, experts say — Read more on ScientificAmerican.com
Researchers have found evidence that the immune response to vaccines like the first two for COVID-19 is both strong and potentially long-lasting. The vaccines used a technology that had never before been used in Food and Drug Administration-approved vaccines. Both vaccines performed well in clinical trials, and both have been widely credited with reducing disease, but concerns remain over how lon
After routing Hernando de Soto and his men, resident Chickasaws repurposed metal objects the Spaniards left behind. Archaeologists unearthed the rare trove of more than 80 metal objects in Mississippi, and believe them to be from de Soto’s 16th-century expedition through the Southeast. The Chickasaws used and adapted the objects as household tools and ornaments, an unusual practice at a time when
This umbrella service could make it easier for communities to find information on climate risks, from drought to floods — Read more on ScientificAmerican.com
Dinosaurs were generally huge, but a new study of the unusual alvarezsaurs show that they reduced in size about 100 million years ago when they became specialized ant-eaters.
An international team of scientists has used high-powered X-rays at the European Synchrotron to show how an extinct South African 200-million-year-old dinosaur, Heterodontosaurus tucki, breathed.
To quickly express genes needed for learning and memory, brain cells snap both strands of DNA in many more places and cell types than previously realized.
Scientists have used data from the Southwest Research Institute-led Magnetospheric Multiscale (MMS) mission to explain the presence of energetic heavy elements in galactic cosmic rays (GCRs). GCRs are composed of fast-moving energetic particles, mostly hydrogen ions called protons, the lightest and most abundant elements in the universe. Scientists have long debated how trace amounts of heavy ions
New research in the June 2021 issue of JNCCN–Journal of the National Comprehensive Cancer Network assesses the quality of cancer care delivered through extended sites coordinated by some of the country's largest cancer centers.
Soils are one of the most diverse habitats on the planet. There are more than thousand microbial species per gram that significantly influence numerous environmental processes.
Male dragonflies lose their wing pigmentation in hotter climates, researchers report. Less pigmentation keeps them cool, but could make it difficult to find a mate, according to their new study. “Our study shows that the wing pigmentation of dragonfly males evolves so consistently in response to the climate that it’s among the most predictable evolutionary responses ever observed for a mating-rel
Nature, Published online: 06 July 2021; doi:10.1038/d41586-021-01861-8 Six scientists explain how COVID-19 has affected their fieldwork and research, as well as opportunities for junior researchers.
A collaborative research project between the five First Nations of the Nanwakolas Council of B.C. and Simon Fraser University is contributing to conservation efforts of the iconic western redcedar tree.
Aryl halides with a benzene ring directly bonded to a halogen atom are readily available and chemically stable, so they are used as a source of benzene rings in organic synthesis. For example, a chemical reaction that generates a highly reactive aryl radical from an aryl halide using a toxic tin compound has long been known as a method for supplying a benzene ring. In recent years, chemical reacti
"Superagers" who performed a challenging memory task in an MRI scanner were able to learn and recall new information as well as 25-year-old participants. Neurons in the visual cortex of brains of superaging older adults retain their selective and efficient ability to process visual stimuli and create a distinct memory of the images. In the future, interventions to train specific areas of the brain
New Zealand's indigenous biodiversity is unique and complex, and it is declining and threatened. People and companies are often uncertain about what they should or should not do to help maintain it. A new paper in the New Zealand Journal of Ecology sets out some comprehensive and concise criteria to provide guidance on what biodiversity is the most important to safeguard from further degradation.
Ultra-deep removal of H2S is important in petroleum refining, natural gas purification and coal chemical industry. However, the industrial catalysts for continuous H2S selective oxidation show poor activity and stability, especially on feed gas containing steam and impurity gas.
Recently, Prof. Wang Zhenyang's research group from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has prepared macroscopic thick three-dimensional (3D) porous graphene films.
Dr. Xue Zhike's group from Yunnan Observatories of the Chinese Academy of Sciences statistically studied six small-scale magnetic reconnections for the first time using the high-resolution data obtained by the 1-meter New Vacuum Solar Telescope (NVST) at the Fuxian Solar Observatory of Yunnan Observatories. The findings were published in The Astrophysical Journal.
During neuropsychological assessments, participants complete tasks designed to study memory and thinking. Based on their performance, the participants receive a score that researchers use to evaluate how well specific domains of their cognition are functioning.
Researchers at IRB Barcelona's Development and Growth Control lab have revealed the mechanisms by which cells enter senescence because of an imbalance in the number of chromosomes. Chromosomal instability is a common trait in most solid tumours, such as carcinoma, and fully understanding its relationship with cancer can help identify new therapeutic targets. The results have been published in the
There is no clinical evidence that the monoclonal antibody aducanumab is beneficial to patients with cerebral amyloid angiopathy, according to a Massachusetts General Hospital neurologist and other officers with the International Cerebral Amyloid Angiography Association. In a letter in The Lancet Neurology, the group cited concerns over safety and efficacy in recommending that aducanumab not be pr
The onset of the Indian summer monsoon has been predicted three months ahead for the last 40 years with the highest precision up until today. The result indicates longer seasonal forecasts based on machine learning may be a way to mitigate the consequences of an erratic monsoon system under future global warming.
Traumatic brain injury (TBI) has a major impact on the lives of affected patients and families. But it doesn't necessarily lead to an increased risk of marital instability, as two-thirds of patients with TBI are still married to the same partner 10 years after their injury, reports a study in the July/August issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Bra
https://doi.org/10.15212/bioi-2021-0011Announcing a new article publication for BIO Integration journal. In this article the authors Xiao'en Shi, Xu Zhang, Xinlu Zhang, Haizhen Guo and Sheng Wang from Tianjin University, Tianjin, China discuss the integration of reactive oxygen species generation and prodrug activation for cancer therapy.
Lonely older adults live at least three fewer years and with poorer health, and being less active, than peers, say experts in ageing research in Singapore and Japan. The first to quantify the impact of loneliness on longevity and quality of life among seniors, the study highlights the problem of loneliness as populations age around the world and COVID-19 measures potentially exacerbate it.
Announcing a new article publication for BIO Integration journal. In this article the authors Daowei Lin, Zhixiao Han, Yanni Fu, Xiaoqiu Zhu, Jin Li, Hui Xu, Jing Wen, Fei Wang and Mingyan Guo from Sun Yat-sen University, Guangdong, China, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China and University of Virginia, Charlottesville, VA, USA discuss how interscalene bra
A new molecular method reveals how different species of toothed whales compete for prey and which food they choose in each other's company. According to previous research, the rough-toothed dolphin Steno bredanensis was supposed to be the absolute top predator of a particular area. Amino acid isotope research shows its trophic level is indeed significantly lower than previously determined.
Faba beans have been an excellent source of food protein since pre-historic times, but about 5% of people can't eat them. Now, an international team of researchers has identified the gene responsible for the production of vicine and convicine, which are harmful to these people.
Since the first known case of COVID-19 in December 2019, the disease has infected over 180 million people and killed nearly four million. A successful group of vaccines that target the coronavirus's spike protein has started to drive down global infection. Supercomputers are now speeding up the process of finding new potential drug candidates that are safe, effective, and can complement vaccines.
Gene silencing therapies are used to interfere with, or 'silence', the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.
What's stressing out bumblebees? To find out, York University scientists used next-generation sequencing to look deep inside bumblebees for evidence of pesticide exposure, including neonicotinoids, as well as pathogens, and found both.
An international team of scientists has used high-powered X-rays at the European Synchrotron, the ESRF, to show how an extinct South African dinosaur, Heterodontosaurus tucki, breathed. The study is published in eLife on 6 July 2021.
Recently, with the help of a steady-state strong magnetic field experimental device, scientists constructed nano-scale borate bioactive glass (Nano-HCA@BG), which can effectively reduce the biological toxicity of borate bioglass, improve the biocompatibility of the glass, and promote the effect of borate bioglass on skin repair.
The change from early years services into formal educational settings has long been considered an integral transition point for young people. Now research from Flinders University asks 'Is service integration actually important to the children?'
Tantalizing evidence has been uncovered for a mysterious population of 'free-floating' planets, planets that may be alone in deep space, unbound to any host star. The results include four new discoveries that are consistent with planets of similar masses to Earth.
Since the discovery of the first fossil remains, the image of the Neanderthal has been one of a primitive hominin. People have known for a long time that Neanderthals were able to fashion tools and weapons. But could they also make jewellery or even art? Researchers analyzed a new find from the Unicorn Cave in the Harz Mountains in Germany and conclude that Neanderthals had remarkable cognitive ab
A 15-year reciprocal transplant study on Guam's native cycad tree, Cycas micronesica, by the Plant Physiology Laboratory at the University of Guam's Western Pacific Tropical Research Center has revealed that acute adaptation to local soil conditions occurs among the tree population and is important in the survival rate of transplanted cycads. The results show that 70% to 100% of cycads that were t
A new study led by scientists at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science is the first to document what coral genes are doing in response to a disease that is rapidly killing corals throughout Florida and the Caribbean. The findings can help to better understand coral immune system as new diseases emerge as the ocean warm.
Scientists from the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Center (DKFZ) have presented a new method for generating metabolic profiles of individual cells. The method, which combines fluorescence microscopy and a specific form of mass spectroscopy, can analyze over a hundred metabolites and lipids from more than a thousand individual cells per hour. Researchers
A research team at POSTECH has uncovered a promising new zeolite, anticipated to be a turning point for the oil refining and petrochemical industries. This research was published in the journal Science on July 2, 2021.
Scientists have explored, for the first time, the viscous fingering (VF, one of classical interfacial hydrodynamics) of an annular ring, where 'fingers' in a fluid of finite volume grow radially, through a combination of experiment and numerical simulation. They demonstrate that the VF of an annular ring is a persistent phenomenon.
The stage is set for a new carbon storage economy to emerge along the Gulf Coast, according to a study led by The University of Texas at Austin, with the region offering ample opportunities to capture and store carbon, and recent state and federal incentives giving an added push to get started.
Human activities like the burning of coal and fossil fuels have caused CO2 to accumulate in the atmosphere, which has significantly affected the Earth's climate. As a result, several scientists are looking for ways to convert CO2 into other valuable organic products, such as 1-butanol, which has shown promise as an alternative fuel for vehicles. This could help reduce our dependence on fossil fuel
A train carrying cargo has finite space. The amount of cargo that can be carried onboard is limited by the size of the cargo and the capacity of the train. Analogously, the amount of time taken up by an optical signal limits the amount of data that can be carried. Temporally shorter signals allow more data to be squeezed into a given time duration, in a method called optical time division multiple
Wetland, forest, and ocean are the three largest ecosystems in the world. Although the area of wetland ecosystem accounts for only 4-6% of the total land area, the carbon reserves of wetland ecosystem accounts for 12-24% of the global land carbon reserves. Under the background of global climate change, research on carbon sequestration of wetland has become an important subject of global carbon cyc
Researchers from Skoltech and the Mental Health Research Center have found 22 lipids in the blood plasma of people with schizophrenia that were associated with lower symptom improvement over time during treatment. The results show that different levels of symptom improvement are associated with different alterations in lipid levels. These can help track resistance to medication that affects over a
Scientists in Singapore are calling for revisions in planned hydropower expansions in light of the rapidly decreasing cost of solar photovoltaic systems.
Participants at the 6th Joint Science Conference of the Western Balkans Process have developed a "10 Point Plan" to control the coronavirus pandemic in the Western Balkans. They also discussed priorities for the time after the pandemic in the Western Balkans and South East Europe. These include a decent healthcare system, climate neutrality, reduction of air and water pollution, and the digitaliza
Dysmenorrhea, painful and severe periods, is a common gynecological disorder with major impacts on quality of life and economic productivity. A new epidemiological study by the open access publisher Frontiers is the first to show that the risk of developing dysmenorrhea increases by more than 30 times for women and girls who are exposed long-term to air pollutants such as carbon and nitrogen oxide
Medical researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have uncovered how signal proteins of the immune system regulate the development of atherosclerosis.
An elegant new algorithm developed by Danish researchers can significantly reduce the resource consumption of the world's computer servers. Computer servers are as taxing on the climate as global air traffic combined, thereby making the green transition in IT an urgent matter. The researchers, from the University of Copenhagen, expect major IT companies to deploy the algorithm immediately.
Using a cast is not more effective than a brace for treating broken ankles, according to University of Warwick researchers – a conclusion that could hasten the decline of the tradition of signing a cast.
Changes in the color and intensity of light pollution over the past few decades result in complex and unpredictable effects on animal vision, new research shows.
While atomic force microscopy and scanning electron microscopy have provided information on the morphology of bitumen surfaces in the past, it was not known whether surface and chemical composition correlate with each other. However, the chemical composition of the surface is of particular interest because oxidation processes take place there, triggered by oxygen-containing molecules in the air su
Metal-organic frameworks (MOF) are crystalline porous organic-inorganic hybrid materials which, by filling their pores with guest molecules, can create functionalities through interactions between the organic-inorganic based frameworks of the MOF (host) and its guest molecules. This host-guest chemistry has the potential to bring 'designable' electrical properties, allowing for a material to be or
A research group at the University of Cordoba has conducted study focused on evaluating the potential of the Sentinel-2 sensor system's configuration to predict the amount of forage on permanent Mediterranean grasslands.
Sleep deprivation – from lifestyle choices, pandemic stress, or late-night computer study – can quickly lead to loss of energy and function during the day and even feelings of anger and depression, an Australian sleep institute study has shown.The study, led by Flinders University, asked 34 health teenagers (20 males) aged between 15 and 17 to spent 10 days and nine nights in a specially designed
Recently, with the help of a steady-state strong magnetic field experimental device, scientists constructed nano-scale borate bioactive glass (Nano-HCA@BG), which can effectively reduce the biological toxicity of borate bioglass, improve the biocompatibility of the glass, and promote the effect of borate bioglass on skin repair.
Covalent organic frameworks (COFs) are an emerging class of polymers with a plethora of potential applications thanks to their crystallinity, stability, and porosity. In a recent study, researchers from the National University of Singapore and Japan Advanced Institute of Science and Technology report a strategy to tune the emission properties of COFs by introducing atoms or small molecular groups
Activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses. A MedUni Vienna research team has now addressed the potential interrelations between AID/APOBECs and the SARS-CoV-2 virus.
We have developed a groundbreaking chemical reaction using an N-heterocyclic carbene catalyst that has a low environmental impact to cleave the bond between the benzene ring of an aryl halide and a halogen atom to generate an aryl radical. Since aryl radicals can thus be easily generated from aryl halides that are widely used in organic synthesis, this is expected to be a powerful technology for p
About 270,000 people suffer a traumatic brain injury in Germany every year. The over-65s are increasingly affected. This is the result of a study conducted by researchers from the BG Kliniken chain of hospitals under the direction of the Neurological Clinic of the Ruhr Universität Bochum (RUB) of the BG University Hospital Bergmannsheil. Falls are often the cause. The researchers advise more preve
Scientists from Tohoku University and the University of Maryland have pinpointed the strong magnetic field of the early sun as the reason behind the radial variation of rock and metal in rocky planets' cores. This magnetic field, which pulled small iron grains inward, explains Mercury's big iron core and why Mars has so little iron in its core.
In 2016, researchers from the University of Liège (Belgium) proposed a new definition of the geological boundary between the Devonian and Carboniferous periods (359 million years). This new definition has been tested by hundreds of researchers around the world and the results are now compiled in a special issue of the journal Palaeodiversity & Palaeoenvironments.
Researchers from the Centre for Sleep and Cognition at the NUS Yong Loo Lin School of Medicine found mindfulness-based therapy to be more effective than an active sleep hygiene programme in improving sleep quality. This study is the first preregistered and adequately powered trial to test sleep-targeted mindfulness-based therapy as a treatment for insomnia.
The Mid-infrared lasers (MIR) with high peak power and high repetition rate operating in the range of 2.7~3 μm have important application in laser surgery and optical parametric oscillator (OPO).
Toyohashi University of Technology developed a chlorine (Cl) substituted Na3SbS4 solid electrolyte for use in all-solid-state sodium (Na) ion batteries. The ionic conductivity of the Na3SbS4 solid electrolyte where sulfur (S) was partially substituted with Cl improved by up to three times. The team also demonstrated that the Cl-substituted Na3SbS4 has a crystal structure framework that allows Na i
Muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This positional memory was found to be based on the expression pattern of the homeobox (Hox) gene cluster, which is responsible for shaping the body during fetal life. These findings are expected to provide clues to elucidate the pathogenesis of muscle diseases lik
The change from early years services into formal educational settings has long been considered an integral transition point for young people. New research from Flinders University now asks, "Is service integration actually important to the children?"
Chang'e-5 (CE-5), the first sample return satellite of China, is expected to land and sample in the Rümker region, north of the Oceanus Procellarum. To select optimal sampling points, researchers analyzed the microwave radiation features in this mare unit, and retrieved the dielectric constant and thickness of lunar regolith based on Chang'e lunar microwave sounder (CELMS) data.
Loss-of-mutations in NGLY1, an enzyme that removes sugar chains, cause a multisystem developmental disorder called NGLY1 deficiency. Researchers from Tokyo Metropolitan Institute of Medical Science (TMiMS), Kyoto University, RIKEN, and T-CiRA in Japan have elucidated the pathogenesis of NGLY1 deficiency. They found that when NGLY1 is deficient, an overwhelming amount of glycoproteins, ubiquitinate
A diagnostic tool called the MasSpec Pen has been tested for the first time in pancreatic cancer patients during surgery. The device is shown to accurately identify tissues and surgical margins directly in patients and differentiate healthy and cancerous tissue from banked pancreas samples. At about 15 seconds per analysis, the method is more than 100 times as fast as the current gold standard dia
Cells play a precise game of telephone, sending messages to each other that trigger actions further on. With clear signaling, the cells achieve their goals. In disease, however, the signals break up and result in confused messaging and unintended consequences. To help parse out these signals and how they function in health — and go awry in disease — scientists tag proteins with labels they can f
New research hints that people with COVID-19 may experience milder symptoms if certain cells of their immune systems “remember” previous encounters with seasonal coronaviruses—the ones that cause about a quarter of the common colds kids get. These immune cells are better equipped to mobilize quickly against SARS-CoV-2, the coronavirus responsible for COVID-19, if they’ve already met its gentler c
Vertical greenery 'planted' on the exterior of buildings may help to buffer people against stress, a Nanyang Technological University, Singapore (NTU Singapore) study has found.
A 15-year reciprocal transplant study on Guam's native cycad tree, Cycas micronesica, by the Plant Physiology Laboratory at the University of Guam's Western Pacific Tropical Research Center has revealed that acute adaptation to local soil conditions occurs among the tree population and is important in the survival rate of transplanted cycads.
Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.
New research has shown myelosuppressive chemotherapy destabilises gut microbiome in patients with solid organ cancers. The study from SAHMRI and Flinders University assessed the gut health of men and women who underwent conventional chemotherapy on cancers, such as breast and lung cancer, without exposure to antibiotics.
At the end of life, people may have to rely on others for help with showering, dressing and going to the toilet. This loss of privacy and independence can be confronting and difficult. Now Australian occupational therapy (OT) researchers have interviewed 18 people receiving palliative care about how they feel about losing independence with self-care, specifically their intimate hygiene, as functio
In defining periods of development, the brain re-organizes connections between its neurons more freely than in its adult form. Researchers around Sandra Siegert at the Institute of Science and Technology (IST) Austria have now discovered two methods to reopen such plasticity: repeated ketamine anesthesia and non-invasive 60 hertz light flickering. The journal Cell Reports now published their findi
* This is a peer-reviewed observational study conducted using Drosophila fruit flies.* The study has uncovered a signalling pathway that causes neural cells to enter divisions after damage. * It is important because the signalling kinases are also seen activated in human Alzheimer's brain neurons post mortem. * The next step is to identify whether the pathway happens in the same way in human neuro
Melbourne researchers have identified a way to improve the immune response in the face of severe viral infections. It is widely known that severe viral infections and cancer cause impairments to the immune system, including to T cells, a process called immune 'exhaustion'. Overcoming immune exhaustion is a major goal for the development of new therapies for cancer or severe viral infections.
What The Study Did: The amount Medicare pays for common generic prescriptions in Part D was compared with prices available to patients without insurance at Costco.
What The Study Did: This national analysis examined the association between the travel distance to the nearest abortion care facility and abortion rate and the effect of reduced travel distance.
What The Study Did: This study in the Lombardy region of Italy examined the association of different health care professional categories and operational units, including in-hospital wards and outpatient facilities, with the seroprevalence of positive IgG antibody tests for SARS-CoV-2 and the likelihood of SARS-CoV-2 infection.
What The Study Did: COVID-19 vaccine-associated messenger RNA (mRNA) wasn't detected in 13 human milk samples collected after vaccination from seven breastfeeding mothers.
What The Study Did: Rates at which patients with type 2 diabetes received diabetes-related health services prior to and during the COVID-19 pandemic are compared in this study.
Newborn mice lacking YAP1 gene are born without bile ducts. Curiously, they don't die in utero and remain physically active, if small and yellow-tinted.
Research in mice reveals how a subset of highly specialized immune cells modulate brain wiring by precision-targeting inhibitory synapses.The work deepens understanding of the versatile repertoire of microglia, the brain's immune cells and resident garbage collectors.The results set the stage for the development of therapies for neurodevelopmental and psychiatric conditions marked by defects in sy
A research team led by Leonor Saude, group leader at Instituto de Medicina Molecular have shown that the administration of drugs that target specific cellular components of a scar upon a spinal cord injury, improves functional recovery. The results now published in the scientific journal Cell Reports set the basis for a new promising therapeutic strategy not only for spinal cord injuries, but pote
South Korea's Ulsan National Institute of Science and Technology (UNIST) has unveiled introduced an innovative way to quantify proton kinetic properties of TCOs.
The neocortex is a layered structure of the brain in which neurons are arranged parallel to each other. This organization is critical for healthy brain function. A team of researchers from Charité – Universitätsmedizin Berlin have uncovered two key processes that direct this organization. Reporting in Science Advances*, the researchers identify one crucial factor which ensures the timely movement
In Europe, S. pneumoniae is the most common cause of community-acquired bacterial pneumonia in adults. Still, very little is known about its colonization within this age group. A team of researchers from ITQB NOVA has now taken a crucial step to clarify the dynamics of carriage of this bacterium in adults.
When you think of North American cuisine, do Indigenous foods come to mind? Chef Sean Sherman serves up an essential history lesson that explains the absence of Native American culinary traditions across the continent, highlighting why revitalizing Indigenous education sits at the center of a better diet and healthier relationship with the planet.
MIAMI–A new study led by scientists at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science is the first to document what coral genes are doing in response to a disease that is rapidly killing corals throughout Florida and the Caribbean. The findings can help to better understand coral immune system as new diseases emerge as the ocean warm.
Researchers today are looking for ways to convert CO2, which is rapidly accumulating in the atmosphere, into other valuable organic products. Now, scientists from the Gwangju Institute of Science and Technology in South Korea have proposed a reaction for the highly selective production of 1-butanol, a valuable alternative fuel, by electro-chemical reduction using copper phosphide electrodes. Their
Since the discovery of the first fossil remains, the image of the Neanderthal has been one of a primitive hominin. People have known for a long time that Neanderthals were able to fashion tools and weapons. But could they also make jewellery or even art? Researchers from Göttingen University and the Lower Saxony State Office for Heritage analysed a new find from the Unicorn Cave in the Harz Mounta
Researchers have developed a new strategy to characterise polymeric transition metal species in acidic solution that has proved promising as an effective method for understanding the polymerisation nature of transition metal (even Ni, Co, REEs), resulting in an efficient method for high-purity metal recovery applications.
In a study published in Physical Review Letters, academician GUO Guangcan's team from University of Science and Technology of China of the Chinese Academy of Sciences made progress in the open quantum system research. This team, collaborating with Austrian theoretical physicist Philip Taranto, demonstrated the non-Markovianity in the multi-step evolution of the open quantum system, and proved the
COVID-19 patients with pneumonia who do not yet require high-flow oxygen therapy benefit from remdesivir: they recover more quickly and the risk of dying is reduced. These benefits are not proven for individuals with more severe disease.
Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected. A new international study led by the University of Bonn now provides new insights. The results are published in the journal Human Genetics and Genomics Advances, but are already available online.
Although the history of bitumen dates back to the third millennium BC, only little is known about its surface structure. Researchers from TU Wien are now shedding light on the nature of the bitumen surface using physicochemical analyses.
A research group at the University of Cordoba has conducted study focused on evaluating the potential of the Sentinel-2 sensor system's configuration to predict the amount of forage on permanent Mediterranean grasslands.
Scientists have used data from the Southwest Research Institute-led Magnetospheric Multiscale (MMS) mission to explain the presence of energetic heavy elements in galactic cosmic rays (GCRs). GCRs are composed of fast-moving energetic particles, mostly hydrogen ions called protons, the lightest and most abundant elements in the universe. Scientists have long debated how trace amounts of heavy ions
A new study published in The Lancet Global Health showed that establishing safe nurse staffing standards in hospitals in Chile could save lives, prevent readmissions, shorten hospital stays, and reduce costs.
An international team including Lancaster University researchers has created a strategy for understanding the evolution of the COVID-19 pandemic throughout the African continent. Their COVID-19 surveillance strategy will improve the ability of African countries to interpret the complex data available to them during the pandemic.
Researchers analyze bone marrow-derived and peripheral blood-derived fibrin clots showing that the former contains more growth factors. They then show that bone marrow-derived fibrin clots can be used for meniscus suturing, even in the inner-most avascular regions, and with a 2-year post-operative follow-up, they show bone marrow-derived fibrin clots support healing better than their peripheral bl
A KAIST immunology research team found that most convalescent patients of COVID-19 develop and maintain T cell memory for over 10 months regardless of the severity of their symptoms. In addition, memory T cells proliferate rapidly after encountering their cognate antigen and accomplish their multifunctional roles. This study provides new insights for effective vaccine strategies against COVID-19,
Based on field survey data of aboveground biomass of herbaceous marsh and the distribution data set of marsh wetland in China, a study led by Prof. JIANG Ming from the Northeast the Institute of Geography and Agroecology, Chinese Academy of Sciences analyzed for the first time the aboveground biomass and its spatial distribution pattern of herbaceous marsh in China. The result was published on Sci
New research shows a completely new way in which cancer cells repair the damage that can otherwise kill them. In both normal cells and cancer cells, the cell membrane acts as the skin of the cells. And damage to the membrane can be life threatening. The interior of cells is fluid, and if a hole is made in the membrane, the cell simply floats out and dies—a bit like a hole in a water balloon. Ther
A team of researchers at the Department of Chemistry and Pharmacy at Friedrich-Alexander University Erlangen-Nürnberg (FAU) has successfully solved the problem of finding a straightforward, cost-effective process for producing hexaarylbenzene molecules with six different aromatic rings. These molecules are important functional materials. The results were published in the journal Angewandte Chemie.
A research team, led by Professor Dai-Sik Kim in the Department of Physics at UNIST has developed a new technique of predefining the crack pattern on a flexible substrate by a sequential deposition of metallic layers which leads to a formation of a'"zero-nanometer gap', or a 'zerogap,' between the adjacent lateral patterns.
Ultrafast imaging plays an important role in physics and chemistry to investigate the femtosecond dynamics of nonuniform samples. The method is based on understanding phenomena induced by an ultrashort laser pump pulse using an ultrashort probe pulse thereafter. The emergence of very successful ultrafast imaging techniques with an extremely high frame-rate is based on wavelength or spatial frequen
New research evaluating the drugs commonly used by rheumatoid arthritis patients suggests two combinations could reduce the risk of heart attack and strokes. The new publication in Frontiers in Cardiovascular Medicine has found that anti-rheumatic drug regimens that include either tumour necrosis factor inhibitors or hydroxychloroquine might significantly protect the endothelium in rheumatoid arth
Was there ever life on Mars? Could life exist there? The latest of nearly 50 missions, NASA’s Mars Perseverance Rover is the opening shot of an ambitious plan to find answers. In this eBook, we… — Read more on ScientificAmerican.com
Scientists have taken the first steps in developing a new method of identifying the movements of criminals using chemical analysis of soil and dust found on equipment, clothing and cars. The locating system allows police or security services to match soil remnants found on personal items to regional soil samples, to either implicate or eliminate presence at a crime scene. The work is presented as
An EPFL study shows that suburban commuters do not necessarily take environmental concerns into account when deciding whether to use their car. Many car commuters—especially those with hectic schedules—feel they have no other choice. That's especially true when it comes to working mothers.
En samtale med en borger sidste år har udløst en alvorlig kritik af Erhvervsstyrelsen, der har fået fire uger til at forklare, hvordan de vil bringe tingene i orden.
Giving mice a single dose of the psychedelic drug psilocybin prompted an immediate and long-lasting increase in connections between neurons, researchers report. Psilocybin, a naturally occurring compound found in some mushrooms, has been studied as a potential treatment for depression for years. But exactly how it works in the brain and how long beneficial results might last is still unclear. The
The multi-centre study identified a microRNA-like small RNA encoded by SARS-CoV-2 in the serum of COVID-19 patients, which can be developed as a non-invasive biomarker for stratification of severe patients from mild/moderate ones and for identification of high-risk individuals before clinical manifestation of severe symptoms. This biomarker ensures proper allocation of patients to different levels
A new study by researchers at the University of Eastern Finland shows for the first time that blood-based measurement of glial fibrillary acidic protein (GFAP) enables distinguishing patients with frontotemporal dementia from those with primary psychiatric disorders or healthy individuals.
The paper describes amperometric biosensors developed for the determination of diclofenac based on planar platinum electrodes modified with carbon nanotubes (CNTs) in chitosan, fullerene C60 in Boltorn H20, gold nanoparticles (Au NPs) in chitosan, and immobilized tyrosinase enzyme.
A team of researchers at the Department of Chemistry and Pharmacy at Friedrich-Alexander University Erlangen-Nürnberg (FAU) has successfully solved the problem of finding a straightforward, cost-effective process for producing hexaarylbenzene molecules with six different aromatic rings. These molecules are important functional materials. The results were published in the reputable journal 'Angewan
Nature, Published online: 06 July 2021; doi:10.1038/d41586-021-01843-w Scientists hope Maria Leptin will bring stability to the European Research Council after predecessor Mauro Ferarri’s controversial tenure.
Vertical greenery 'planted' on the exterior of buildings may help to buffer people against stress, a Nanyang Technological University, Singapore (NTU Singapore) study has found.
Behavior is one indicator of fish welfare. If we have a good understanding of how fish behave in their normal state, as well as in unusual environmental conditions, we can potentially detect events early on that might harm farmed fish, like salmon, so we can prevent problems.
It's no secret that women live longer than men. But fellas, if we told you there was one thing that may increase your lifespan, would you do it? New Zealand researchers, in collaboration with Allen Distinguished Investigator Steve Horvath from UCLA, have demonstrated that castration of male sheep delays aging of DNA compared to intact males, and that it also drives feminine characteristics of DNA
To create the hazard maps, the study combined development data from Zillow with natural disaster risk models. The hazard hotspots describe areas of the U.S. where the likelihood of a natural disaster falls in the top 10 percent. The researchers hope better data will help policymakers make better plans for the future. Natural hazards like hurricanes and wildfires may pose increasing threats to the
A new study shows how urbanization has influenced anthropogenic CO2 and air pollutant emissions across all world regions. The results show that by 2015 urban centers were the source of a third of global anthropogenic greenhouse gases, and the majority of air pollutant emissions.
Researchers have shown how pharmacological activation of the protein p53 boosts the immune response against tumors. The results can be of significance to the development of new combination therapies that will give more cancer patients access to immunotherapy.
"Historically lax" regulations around pollution control have led to much higher levels of mercury emission from coal-fired power stations in Victoria, according to a new study from The Australian National University (ANU).
We know coal-fired power stations can generate high levels of carbon dioxide, but did you know they can be a major source of mercury emissions as well?
Nature, Published online: 05 July 2021; doi:10.1038/d41586-021-01856-5 How biomedical researchers are beginning to probe the possibilities of quantum computing. Plus: the auroras of Mars and why COVID vaccines won’t reach many people until 2023.
If you think about skincare, what might come to the front of your mind might be lavish ads of beautiful celebrities targeting their skincare products at women. But women aren’t the only people who need to look after their skin: men and women both go through many of the same factors that contribute to aging, skin damage, and wrinkles. It just seems like the market is much more opaque to men intere
Agriculture in sub-Saharan Africa is under-performing, leaving 30% of people in the region food insecure. Food insecurity means that not all people, at all times, have physical, social, and economic access to sufficient, safe, and nutritious food that meets their food preferences and dietary needs.
People are really good at recognizing faces. One of my lecture bits is to show a picture of a famous person for a fraction of a second (as fast as I can make the picture cycle in Powerpoint). The vast majority of the audience has no problem placing this face in their memory from just a quick glance. How does the brain accomplish this feat? That is something that neuroscientists are still working
The COVID-19 pandemic will change a lot about the way knowledge is produced, especially in the fields of science, technology, engineering and medicine. Social movements such as Black Lives Matter have also increased awareness of significant economic inequalities along racial and geopolitical lines. People have new tools and new ways of working, many of which have heightened awareness of systemic i
Researchers are taking to the skies to help see what is happening underground in a new project that aims to improve one of Australia's largest grain crops—barley.
In September each year, South Africa's Gauteng province turns purple. The cities of Johannesburg and Pretoria are well covered with trees—and jacarandas (Jacaranda mimosifolia), with their purple blooms in late spring, are a prominent part of this urban forest.
Nature, Published online: 06 July 2021; doi:10.1038/d41586-021-01824-z Well-meant changes to improve science could become empty gestures unless underlying values change.
Nature, Published online: 06 July 2021; doi:10.1038/d41586-021-01813-2 Russia's vaccine is in use in nearly 70 nations, but its adoption has been slowed by controversies and questions over rare side effects, and it has yet to garner World Health Organization approval.
De män som var vältränade i sena tonåren har inte lika ofta behövt sjukhusvård för covid-19. Det visar forskning från Göteborgs universitet. Män som gjorde bra ifrån sig på mönstringens fysiska test i sena tonåren har i högre grad kunnat undvika sjukhusvård när de under pandemin fått covid-19, uppemot 50 år senare. Studien från Göteborgs universitet är baserad på det svenska värnpliktsregistret,
The retractions appear to be trickling in for Thomas Webster, a once-prominent chemistry researcher who left his post at Northeastern University after nearly 70 of his papers were flagged on PubPeer for concerns about the data in the studies. But while the publisher of a journal he co-founded — and left earlier this year — … Continue reading
Chronic pain affects about 40% of the UK population. While there is growing recognition that pain can be an illness in and of itself, there is still a lot we don’t know. Anand Jagatia hears from fibromyalgia sufferer Vicky Naylor on what it’s like to live with chronic pain, and the Guardian’s science correspondent Linda Geddes about the causes for these sometimes debilitating conditions. Help supp
Att behandla hjärntumörer är svårt på grund av de barriärer som finns runt hjärnan. Nu har forskare gjort en upptäckt som kan ändra på det. Gliom är en dödlig hjärntumör med mycket dålig prognos. En anledning till att det är så svårt att behandla hjärntumörer är att immunsystemet, som är designat för att hitta och förstöra främmande celler, inklusive cancerceller, har svårt att komma åt tumören p
In Arizona, a long-running drought and resulting water stress has contributed to the die-off of as many as 30 percent of the native junipers, even though they are accustomed to a dry climate. Over the last decade, more than 129 million trees died because of drought. Here’s what’s happening inside their veins.
Scientific Reports, Published online: 06 July 2021; doi:10.1038/s41598-021-93431-1 Dosimetry during adjuvant 131 I therapy in patients with differentiated thyroid cancer-clinical implications
Scientific Reports, Published online: 06 July 2021; doi:10.1038/s41598-021-93436-w Differences among [ 18 F]FDG PET-derived parameters in lung cancer produced by three software packages
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24452-7 Hybrid devices based on electrons on helium may find application in quantum devices. Here the authors demonstrate surface acoustic wave driven acoustoelectric transport of electrons on superfluid helium.
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24437-6 Hydropower dams in the Lower Mekong basin have profound impact on the riverine ecosystems. Here the authors use strategic dam planning and power system modelling to show that there are economically and technically feasible alternatives to these dams with solar energy and power trading.
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24357-5 Sleep is known to promote memory consolidation, but the extent to which this is dependent on the memory’s relevance remains unclear. Here, the authors use a brain decoding approach to show that neural representations of rewarded experiences undergo a privileged reactivation during sleep, favouring their consolid
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24444-7 Lactate levels in blood change during hypoxia or exercise, however whether this variable is sensed to evoke adaptive responses is unknown. Here the authors show that oxygen-sensing carotid body cells stimulated by hypoxia are also activated by lactate to potentiate a compensatory ventilatory response.
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24345-9 While many genetic loci have been found to be associated with disease, not many have had their causal variants and mechanisms investigated. Here, the authors experimentally dissect two loci near GDF5 which are associated with two different joint disorders and which map to independent regulatory elements.
Nature Communications, Published online: 06 July 2021; doi:10.1038/s41467-021-24284-5 Seawater electrolysis is promising for grid-scale H2 production without freshwater reliance, but high energy costs and detrimental Cl chemistry reduce its practical potential. Here, authors developed an energy-saving hybrid seawater electrolyzer for chlorine-free H2 production and N2H4 degradation.
Reningsprocessen för avloppsvatten är ofta komplicerad, dyr och ineffektiv. Textilier kan vara lösningen på problemet visar forskning från Borås universitet. Hushåll, industrier och jordbruk världen över producerar dagligen tonvis av giftigt avloppsvatten. Trots omfattningen av problemet har vi i decennier hållit fast vid konventionella biologiska metoder för rening av avloppsvattnet, metoder som
Den vanligaste klasstillhörigheten i umgängeskretsen kan skvallra om vilka politiska åsikter vi har – oavsett vilken klass vi själva tillhör. Det visar en svensk studie som nyligen publicerats i European Sociological Review.
Ethiopia says it has started the next phase of filling a controversial mega-dam on the Nile River, Egyptian authorities said Monday, raising tensions ahead of an upcoming UN Security Council on the issue.
A major construction project in wetlands seen as one of the "green lungs" of smog-choked Mexico City has raised concerns for the future of the UNESCO World Heritage Site.
Tropical storm Elsa was moving over the Florida Straits toward the southern US state Tuesday after battering Cuba with drenching rain and strong winds, but left the Caribbean island without major damage.
The silvery blue waters of the Great Salt Lake sprawl across the Utah desert, having covered an area nearly the size of Delaware for much of history. For years, though, the largest natural lake west of the Mississippi River has been shrinking. And a drought gripping the American West could make this year the worst yet.
Extrema skillnader i flyghöjd mellan dag och natt kan vara ett, tills nu, oupptäckt mönster bland flyttfåglar. Den reflexionen gör forskare vid Lunds universitet i en studie på dubbelbeckasiner där de även uppmätt nytt höjdrekord för flyttfåglar på 8700 meter. Dubbelbeckasiner är en vadarfågel som häckar i bland annat Sverige och tillbringar vintern i områden vid ekvatorn i Afrika. Från tidigare
Mayim Bialik is a neuroscientist. In her TV commercials for Neuriva Plus she asserts that it is backed by strong science. I don't think so. The post first appeared on Science-Based Medicine .
PLUS. Ministre fra fem EU-lande har sendt et brev til Europa-Kommissionen med et ønske om ikke at anse atomkraft som en grøn investering – stik imod konklusionen fra en ekspertrapport fra april.
AGI Laboratory’s long-term goal is to make it easier to build AGI and move towards AGI and Superintelligent systems. Given where we are at from a research standpoint this is in implementing cooperative collective superintelligence systems such as Uplift, as well as e-governance voting, and in infrastructure such as the N-Scale database designed to grow on the fly without human interventions. This
Scientists have taken the first steps in developing a new method of identifying the movements of criminals using chemical analysis of soil and dust found on equipment, clothing and cars. The locating system allows police or security services to match soil remnants found on personal items to regional soil samples, to either implicate or eliminate presence at a crime scene. The work is presented as
A prospective cohort study found that treatment at an infusion center (IC) is associated with substantially better outcomes than treatment in the emergency department (ED) for patients with sickle cell disease (SCD) and uncomplicated vaso-occlusive crises. The findings are published in Annals of Internal Medicine.
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