F or a generation , American cops have aggressively policed many urban neighborhoods based on the premise that cracking down on minor street disorder would avert spikes in more serious crime. While reviled by some, the so-called broken-windows theory is still defended by many in law enforcement. Maybe it’s time they applied it to themselves. According to the broken-windows theory, just as a build
The city of Beijing has tested 1.1 million people in less than a week and has halted many flights, but has not imposed the citywide lockdowns used in provincial outbreaks.
Administering the MMR (measles, mumps, rubella) vaccine could serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection, say a team of experts in this week's mBio, a journal of the American Society for Microbiology.
T he story I can’t get out of my head is the death of Philando Castile. In the summer of 2016, in the suburbs of St. Paul, Minnesota, Castile, a 32-year-old black man, was pulled over in a car he was driving, along with his partner and her 4-year-old daughter. “How are you?” Castile asked the approaching officer, according to a published transcript. “Good,” said the cop, a 28-year-old Hispanic Am
When the French journalist Sonia Dridi talks about her experience covering the past few weeks of protests against racism and police brutality in the United States, she often thinks back to another story she covered. “The scene, seeing everyone running around Lafayette Square, really made me think of Egypt,” Dridi, a Washington correspondent for the broadcaster France 24 and other French media out
A review of scores of studies on antidepressants has been retracted because it used an incorrect analysis. The original paper, published in JAMA Psychiatry on February 19, 2020, looked at individual differences in patients taking antidepressants and concluded that there were significant differences beyond the placebo effect or the data’s statistical noise. The paper earned … Continue reading
The group has published much of its advice – but it’s not there to make political judgments about how this advice gets used • Ian Boyd is a contributor to the Scientific Advisory Group for Emergencies Some of my earliest memories are of wanting to study science. It has been a privilege to have had the opportunity to make this my career, and it has been a pursuit in search of making the world a be
PM says ‘watch this space’ when asked about physical distancing measures and schools returning Coronavirus – latest updates See all our coronavirus coverage The UK has lowered its Covid-19 alert level from 4 to 3, meaning transmission of the virus is no longer judged to be “high or exponentially rising”, raising expectations that physical distancing restrictions could be cut. The downgrade, which
A criminologist and sociologist explains how quantitative studies can uncover inequalities in criminal justice experiences between races, including police violence, incarceration, and mental health. But the studies are still limited by the absence of a national public database tracking police use of force.
East Africa is bracing for a third outbreak of desert locusts, with billions of the destructive insects about to hatch and threaten food supplies in a region already reeling from damaging rains and the coronavirus pandemic.
East Africa is bracing for a third outbreak of desert locusts, with billions of the destructive insects about to hatch and threaten food supplies in a region already reeling from damaging rains and the coronavirus pandemic.
A group of researchers, led by a UNSW sustainability scientist, have reviewed existing academic discussions on the link between wealth, economy and associated impacts, reaching a clear conclusion: technology will only get us so far when working towards sustainability—we need far-reaching lifestyle changes and different economic paradigms.
Many countries are failing to comply with the non-binding commitments of the Paris Agreement, making it increasingly clear that we have to reconsider how to ensure collective action to limit global warming to less than 2°C above preindustrial levels. A new IIASA-led study supports a different approach to designing an international climate agreement that would incentivize countries to cooperate.
Differences in the rate that genetic mutations accumulate in healthy young adults could help predict remaining lifespan in both sexes and the remaining years of fertility in women, according to University of Utah Health scientists. Their study, believed to be the first of its kind, found that young adults who acquired fewer mutations over time lived about five years longer than those who acquired
Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have shed light on the reproductive role of 'dark matter' DNA – non-coding DNA sequences that previously seemed to have no function.Their findings, published today in Nature Communications, have revealed that a specific non-coding genomic region is essential for the proper development of the male and female
Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating their natural painkilling and antidepressant properties. These findings were p
One person who’s unlikely to fall ill at Donald Trump’s Tulsa rally is Donald Trump. When jubilant supporters peel off their masks and whoop their approval as he torches Joe Biden, rest assured that the president will be a safe distance from any pathogens spat into the air. It’s the crowd that’s at the most risk. Trump’s arrival at the BOK Center on Saturday plunks him into the safest of spaces.
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16929-8 Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16948-5 Amides are versatile synthetic building blocks, however the general stability of the amide bond makes its selective transformation challenging. Here, the authors report a chemodivergent transformation of primary, secondary and tertiary amides by using 1,1-diborylalkanes as pro-nucleophiles.
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16637-3 MicroRNA2118 induces the production of phased small interfering RNAs (phaisRNAs) in plants. Here the authors show that rice miR2118 is required for both male and female fertility and supports the production of atypical U-rich 21 nt phasiRNAs that are abundant in anther walls.
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16887-1 Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory necroptotic cell death program. Here the authors show that MLKL trafficking and plasma membrane accumulation are crucial necroptosis checkpoints, and that accumulation of phosphorylated MLKL at intercellular junctions promote
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16922-1 Force-dependent formation of the talin-vinculin complex reinforces actin anchoring to focal adhesions, but how different talin-binding proteins respond to force is unclear. Here authors use an in vitro microscopy assay and show that the actomyosin force triggers the dissociation of RIAM from several talin domain
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16823-3 The necroptotic cell death pathway involves signaling through pseudokinases. Here the authors define the structural determinants of species specificity in necroptosis signaling mediated by the essential necroptotic effector pseudokinase, Mixed Lineage Kinase Domain-Like (MLKL).
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16962-7 Bioproduction of hyaluronan needs increases in yield and greater diversity of the molecular weights. Here, the author increases hyaluronan production and diversifies the molecular weights through engineering the hyaluronan biosynthesis pathway and disruption of Corynebacterium glutamicum encapsulation caused by
Nature Communications, Published online: 19 June 2020; doi:10.1038/s41467-020-16863-9 In information processing applications, directional amplifiers are key components which can be realized in very different systems. Here, the authors present a theoretical framework based on the introduction of a topological invariant that helps to understand directional amplification in coupled cavity arrays.
Black communities have been telling the nation, for more than a century, that they have been targeted, beaten, falsely accused and killed by the police and other institutions meant to protect them. They have not been believed until recently, when the rise in camera phones and social media finally enabled them show and disseminate proof. Even after the video of George Floyd's death on May 25, 2020
The shift, quietly disclosed on a government website, highlights how the Trump administration is favoring development of vaccines over treatments for the sickest patients.
SARS-CoV-2, the virus that causes Covid-19, is especially lethal to older people, and it has spread quickly in the close quarters of many nursing homes, where at least 32,000 residents have died. The devastation has energized calls for a drastic solution: closing nursing facilities altogether.
Plants in dense tropical forests are able to mask their chemical scents in order to avoid being detected and eaten by insects—a key advantage in the "information arms race" between themselves and plant-eating herbivores, according to a new study.
Plants in dense tropical forests are able to mask their chemical scents in order to avoid being detected and eaten by insects—a key advantage in the "information arms race" between themselves and plant-eating herbivores, according to a new study.
Your questions answered on what type of mask to wear to cut the risk of getting Covid-19 Coronavirus – latest updates See all our coronavirus coverage Yes. Different types of mask offer different levels of protection. Surgical grade N95 respirators offer the highest level of protection against Covid-19 infection, followed by surgical grade masks. However, these masks are costly, in limited supply
The way animals compete and choose within their struggle to reproduce could have big consequences for extinction risk, according to new research from the University of East Anglia.
Several years ago, planetary scientist Lynnae Quick began to wonder whether any of the more than 4,000 known exoplanets, or planets beyond our solar system, might resemble some of the watery moons around Jupiter and Saturn. Though some of these moons don't have atmospheres and are covered in ice, they are still among the top targets in NASA's search for life beyond Earth. Saturn's moon Enceladus a
The way animals compete and choose within their struggle to reproduce could have big consequences for extinction risk, according to new research from the University of East Anglia.
This report is part of “ The global AI agenda ,” a thought leadership program by MIT Technology Review Insights examining how organizations are using AI today and planning to do so in the future. Featuring a global survey of 1,004 AI experts conducted in January and February 2020, it explores AI adoption, leading use cases, benefits, and challenges, and seeks to understand how organizations might
PLUS. Det kan vise sig at være den helt store gevinst, men medarbejderaktier kan også ende som en kedelig nitte, der koster dyrt, fordi de erstattede en lønforhøjelse – eller fordi de blev tvangsindløst.
The society journal Bioscience Reports fell prey to many fraudulent papers. Cheshire counted around 50 with problematic figures, just for the last year.
Nature, Published online: 19 June 2020; doi:10.1038/d41586-020-01863-y Results from the inaugural study will reveal crucial information about the deepest worries, hopes and triumphs of postdocs around the world.
I går kom det offentliges smittestop-app. Jeg tror personligt, at den kan være et vigtigt redskab til at få åbnet helt op for samfundet. Vel at mærke, hvis folk vil downloade den og betragte sig selv som smittede, hvis appen giver dem en advarsel. Men den slags overvågning skaber naturligvis beky…
News updates: Education secretary to reveal details of £1bn funding package for schools to help pupils catch up on lessons missed during the coronavirus lockdown English schools to get £1bn to help pupils catch up after lockdown 4.5m people in UK forced to become unpaid carers due to Covid crisis Coronavirus global updates All our coronavirus coverage 8.32am BST Two in five adults in the UK feel
Proposed 100km circular tunnel would be four times as big and six times as powerful as LHC As the largest scientific instrument on the planet enters its twilight years, Cern scientists have been facing the question of what next after the Large Hadron Collider (LHC). Following extensive debate, they appear to have landed on an answer: go bigger or go home. Cern’s council is expected to announce it
Continued burials of coronavirus victims in Chile, dinosaur art in Shanghai, an outdoor town meeting in Massachusetts, ongoing protests against police brutality and systemic racism worldwide, workout pods in California, the phased reopening of Grand Teton National Park, a horse named Mr. Glitter Sparkles in England, the Skyline Drive-In in Brooklyn, the removal of a Confederate statue in Houston,
'We believe that those with persistent leak encompassing months or years are more likely to develop CTE,' says Prof. Friedman. 'Many players seem to repair their BBB quickly, and if they do not suffer from repeated TBIs [traumatic brain injuries] or are not sensitive to brain injury, they are not likely to develop CTE.'
Researchers from Kanazawa University retrospectively analyzed children with refractory or relapsed high-risk neuroblastoma who were treated with high-dose 131 I-metaiodobenzylguanidine at Kanazawa University Hospital. They showed that within a 5-year period, this therapy could provide a favorable prognosis without severe non-hematological side effects. These findings could provide new insights int
Pregnant and postpartum women are more likely to experience depression and anxiety since the coronavirus pandemic began, according to a recent study at the University of Alberta. These mental health struggles have been linked to increased risk of premature delivery, reduced mother-infant bonding, and developmental delays in infants. However, the same study also found that women who engaged in phys
Jeg håber, vi kan fastholde sammenholdet og de gode ideer fra corona-pandemien, når hverdagen for alvor begynder igen og pengestrømmen tørrer ind, skriver Torben Mogensen.
Problem-læger får alt for lang snor, mens mistænkte læger hænger i gabestokken i månedsvis. Så længe det står på, er visionen om en stærk læringskultur en utopi.
Et politisk flertal kræver en evaluering af Styrelsen for Patientsikkerhed hurtigst muligt. Sundhedsminister Magnus Heunicke skal nu redegøre for sine evalueringsplaner. Minister og styrelsen er tavse i sagen.
ANALYSE: Camilla Rathcke er den fornuftige favorit, men bag hende er flere kandidater, der kan true hende som oplagt valg til ny lægeformand. Som i øvrigt overtager en lægeforening, der inden få år møder en milepæl, der kan splitte foreningen.
To danske studier ved Dansk Center for Partikelterapi skal kaste lys over, om der er hold i forestillingen om, at partikelterapi med protoner er mere skånsom end konventionel røntgenstråling ved behandling af brystkræft og hovedhalskræft. Studierne er allerede nu et trækplaster for kræftforskere fra hele verden.
PLUS. Selvom SSI ikke modellerer længere, fordi smittetrykket er så lavt, så modtager instituttet stadig data fra teleindustrien, som overlæge hos SSI kalder ‘baggrundsdata’, der skal gemmes til fremtidige modelleringer.
Extra flexibility. (Ashkan Forouzani via Unsplash/) Tablets can be perfect for long trips, waits in the doctor’s office, or a wind-down weeknight on the couch, but it doesn’t make a ton of sense to spring for one when your laptop does nearly the same thing. That’s why 2-in-1 laptops are becoming increasingly popular. You’ve got the stability of a keyboard for your work day and the portability of
Narwhals, recognizable by their large single tusk, make distinct sounds that are now being analyzed in depth by researchers. — Read more on ScientificAmerican.com
Out of the more than 70 million displaced people worldwide, only three percent have access to higher education. The Global Education Movement (GEM) is on a mission to change that with the first large-scale initiative of its kind to help refugee learners get bachelor's degrees and create pathways toward employment. Hear from students and the program's executive director, Chrystina Russell, about ho
By analyzing longevity data for professional Japanese traditional artists, researchers at Tokyo Institute of Technology have found that Kabuki actors, known for their vigorous movements, surprisingly had shorter lifespans compared with other traditional arts performers who lead mostly sedentary lifestyles. The findings suggest that job-related strenuous exercise throughout life may not necessarily
Every weekday evening, our editors guide you through the biggest stories of the day, help you discover new ideas, and surprise you with moments of delight. Subscribe to get this delivered to your inbox . WILFREDO LEE / AP Juneteenth, as my colleague Vann R. Newkirk II put it, celebrates a “belated liberation.” On June 19, 1865, more than two years after President Lincoln issued the Emancipation P
Researchers working on more than 200 vaccines, says WHO; global deaths pass 450,000; Brazil nears 1m cases. Follow the latest updates US questions new China outbreak figures Beijing outbreak may have started a month earlier than thought WHO eyes 2bn vaccine doses by end of 2021 Coronavirus map of the US: latest cases state by state See all our coronavirus coverage 1.50am BST The United States doe
Facing criticism over workplace safety, the company is using cameras, sensors, and augmented reality to warn employees when they're too close to one another.
The way canaries remember the last few seconds of their singing lets them to produce much more complex, language-like songs, researchers say. When a canary sings, it maintains a memory trace of the notes produced in the previous five to 10 seconds, a process that allows the bird to produce songs with long-range rules or structure similar to sentences, according to the new study. In the project, r
There needs to be broader study of how biological sex differences affect outcomes with COVID-19, researchers argue in a recent paper. Though it’s still unclear exactly why, what is clear is that men are suffering worse fates than women when it comes to COVID-19, regardless of geography or age . A variety of data from outbreaks across the world has established this, and researchers like Johns Hopk
The first dinosaur eggs had a soft shell, researchers say. For many years there was little fossil evidence of dinosaur eggs, and all known examples were characterized by thick, calcified shells—leading paleontologists to speculate that all dinosaur eggs were hard-shelled, like those of modern crocodiles and birds. “These dinosaurs buried their eggs in clutches, like modern animals that lay soft e
Elite athletes who adopted simple oral health measures, such as using high fluoride toothpaste and cleaning between their teeth, reported significantly reduced negative effects on performance related to poor oral health, finds a study led by UCL.
New research shows that removing sexual competition and choice through enforced monogamy creates populations that are less resilient to environmental stress, such as climate change.The research team looked at how flour beetles coped with environmental and genetic stress after they had evolved under monogamous versus polyandrous mating patterns.The researchers say that their findings should apply t
New research shows that vapers have been largely reassured by recent EU regulations, but some have been pushed to the black market for stronger hits. The researchers say their findings are particularly important during the Covid-19 pandemic (since switching from smoking to vaping improves cardiovascular and respiratory conditions, smokers who switch to vaping might be expected to have a better pro
COVID-19 patients with extremely high levels of the stress hormone cortisol in their blood are more likely to deteriorate quickly and die, according to new research published today.
As evidence mounts for the possibility of SARS-CoV-2 infecting various animals, scientists at UCL say a global effort is needed to reduce the risk of the virus later returning to people, in a comment piece published in The Lancet Microbe.
While most cats and dogs are still being fed 'conventional' wet and dry food, there has been a distinct shift in feeding practices over the past decade to include raw and home-made foods, particularly in Australia, finds an international study, published in this week's issue of Vet Record.
While most cats and dogs are still being fed 'conventional' wet and dry food, there has been a distinct shift in feeding practices over the past decade to include raw and home-made foods, particularly in Australia, finds an international study, published in this week's issue of Vet Record.
While most cats and dogs are still being fed 'conventional' wet and dry food, there has been a distinct shift in feeding practices over the past decade to include raw and home-made foods, particularly in Australia, finds an international study, published in this week's issue of Vet Record.
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