Voting machines in one polling place had no power cords. The problems follow a big purge of voter rolls by the secretary of state, who is running for governor.
Med ny forskning i materialeteknologi er forskere kommet nærmere et batteri, der kan anvendes i elektriske fly. Batterierne boostes med magnetiske nanopartikler, kombineret med magnetfelter, der letter ionernes passage gennem batteriet og gør det stærkt nok til at bringe et fly i luften.
Five years after one particular tiny thorn snail from Panama was identified as new to science, it is described in a scientific article in the open-access journal ZooKeys. The official discovery only became possible after earlier this year glassy shells were collected from the La Amistad International Park, Chiriquí, Panama. Successfully recognised thanks to modern computed tomographic scans, the s
Hearing has long been suspected as being 'on' all the time — even in our sleep. Now scientists are reporting results on what is heard and not heard during sleep and what that might mean for a developing brain. At the Acoustical Society of America's 176th Meeting, Nov. 5-9, researchers from Vanderbilt University will present preliminary results from a study in which preschool children showed memor
Philosopher Ben Constant explains how democracy today is nothing like what it used to be. His arguments show us that debates around what freedom actually is can go in very strange directions. Remember how busy the Athenian citizens were next time you think there are too many questions on the ballot. When people talk about freedom and democracy, they often trace the lineage of both back 2,000 year
Arlington, Virginia and New York City are doing a victory lap after The New York Times reported Monday that Amazon is planning to split its second headquarters, called HQ2, between the two cities, bringing high-paying jobs to both locations. The report comes after hundreds of cities across the country went through a more-than-yearlong bidding process for the headquarters, which Amazon originally
The Bill and Melinda Gates Foundation and the Wellcome Trust agree not to cover the fees that some hybrid open-access journals charge authors to make their work freely available.
Moths are a mainstay food source for bats, which use echolocation to hunt their prey. Scientists are studying how moths have evolved passive defenses over millions of years to resist their primary predators. While some moths have evolved ears that detect the ultrasonic calls of bats, many types of moths remain deaf. In those moths, researchers have found that the insects developed types of 'stealt
Scientists havedesigned a device that can induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by 'kick-starting' tissue repair at the amputation site. Their findings introduce a new model for testing 'electroceuticals,' or cell-stimulating therapies.
New research revealed today highlights the power of animal studies to explore mechanisms of opioid addiction, withdrawal, and relapse to inform new prevention strategies and treatments for people.
O, election day! In the ruddy twilight of each year, as autumn incarnadines the republic’s plump pastures and luxuriant hills, its people gather for that most felicitous and humbling of civic offices: to choose our elect, to decide who will rule. With renewed revolutionary vigor this mighty tide sweeps the continent, intermingling the wise Delaware and the ferocious Klamath, making so strong a to
New research revealed today highlights the power of animal studies to explore mechanisms of opioid addiction, withdrawal, and relapse to inform new prevention strategies and treatments for people. The findings were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
Here's another reason you might be exhausted after that preschool birthday party: Your brain had to work to figure out who actually asked for more ice cream. 'What we found with two-and-a-half-year-olds is that it's amazingly hard for adults to identify who's talking,' said Angela Cooper, a postdoctoral researcher at the University of Toronto. Cooper's co-authored research will be presented at the
To find ways to improve man-made active sensing, scientists worldwide study the sonar systems of bats and dolphins. During the Acoustical Society of America's 176th Meeting, Nov. 5-9, Laura Kloepper will compare bat and dolphin sonar systems, describing her work on how the two animals cope with acoustic interference. She'll use her findings to argue why bats have the superior system.
Researchers at the University of Waterloo have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests.
Today is Election Day, and it’s hard to believe that anyone feels cheerful about it. Relieved? Maybe. But positive? Democrats are riven with anxiety about whether they can win back the House. Republicans are riven with anxiety about whether they can hold it. President Donald Trump has chosen a closing argument for the campaign that’s rooted in racist fearmongering and lies . The nation is still r
Fumiko Hoeft (photo by Peter Morenus/UConn) Each year, the Society for Neuroscience recognizes outstanding neuroscientists who have strongly added to public education and awareness about the field. The Dana Foundation sponsors these awards. This year’s award was presented to Fumiko Hoeft , M.D., Ph.D., professor of psychology and director of the Brain Imaging Research Center (BIRC) at the Univers
Fox News says it doesn't condone "any talent participating in campaign events." It's not the first time Hannity has been rebuked by network executives for his political activism. Still, it's not clear whether the network plans to penalize Hannity, partly because he's the most-watched host in cable news. None On the morning of President Donald Trump's last rally before the midterm elections, Sean
Fox News says it doesn't condone "any talent participating in campaign events." It's not the first time Hannity has been rebuked by network executives for his political activism. Still, it's not clear whether the network plans to penalize Hannity, partly because he's the most-watched host in cable news. None On the morning of President Donald Trump's last rally before the midterm elections, Sean
Manganese is known for making stainless steel and aluminum soda cans. Now, researchers say the metal could advance one of the most promising sources of renewable energy: hydrogen fuel cells. As reported in Nature Catalysis , the discovery could eventually help solve hydrogen fuel cells’ most frustrating problem: they’re not affordable because most catalysts are made with platinum, which is both r
In a Veterans Affairs study, a humanmade compound based on a brain hormone spurred the growth of cancer in Petri dishes but enigmatically had the opposite effect in mice. The compound and others like it are being looked at not only for their effect on cancer, but for their ability to regrow healthy tissue to heal damaged hearts and other organs.
A new immunotherapy screening prototype can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs.
The number of overdose deaths involving methamphetamines and amphetamines in the state of Ohio increased more than 5,000 percent over the course of eight years, according to new data.
Imagine preparing for a job interview or a promising first date. You probably consider your outfit and general grooming—a fresh shower, plus hair products and makeup, if you use them. Glasses or contacts? Hair up or down? Various decisions signal different levels of erudition or sexual appeal, and people spend considerable time and money trying to use them to their advantage in high-stakes situat
Computer algorithms are playing a growing role in analyzing hydrophone audio data when monitoring marine life, but human listeners can complement and enhance these algorithms. A project known as Orcasound has produced a web application that will enable citizen scientists to listen to livestreaming audio from hydrophones near the San Juan Islands.
Computer algorithms are playing a growing role in analyzing hydrophone audio data when monitoring marine life, but human listeners can complement and enhance these algorithms. A project known as Orcasound has produced a web application that will enable citizen scientists to listen to livestreaming audio from hydrophones near the San Juan Islands. Researchers will describe the new web app and the v
If Democrats take back the House on Tuesday, it will have been against all odds thanks to gerrymandering that has skewed so heavily toward Republicans.
A crucial part of studying southern resident killer whales is finding them and quickly alerting experts to send boats out to collect fecal samples or prey fragments to better understand what the whales are eating.
Scientists Resurrect Ancient Versions of Life's Molecular Machinery Heat-tolerant prehistoric enzymes might help produce valuable chemicals and biofuels. AncientEarth_topNteaser.jpg Artist's conception of an early Earth. Image credits: NASA Technology Tuesday, November 6, 2018 – 15:45 Catherine Meyers, Editor (Inside Science) — In the 1990 Michael Crichton novel "Jurassic Park," scientists resur
Researchers have discovered that the bacteria in the water in a large exhibit at Georgia Aquarium are similar to those that exist naturally in the ocean. Sea creatures need to go to the bathroom, too, and in aquariums, that creates the task of cleaning the water of waste like ammonia, nitrites, and nitrates. Good bacteria break down nitrogen compounds at aquariums, and the new study shows that so
Researchers have identified a type of skeletal stem cell in the “resting zone” of the epiphyseal growth plate—a special cartilaginous tissue and an important driver for bone growth. Skeletal stem cells are valuable because it’s thought they can heal many types of bone injury, but they’re difficult to find because researchers don’t know exactly what they look like or where they live. Locating skel
Nexus Media News Scientists are getting closer to making self-healing materials a commercial reality. Plants self-repair and regenerate naturally. Your devices could soon do the same.
A new immunotherapy screening prototype developed by University of California, Irvine researchers can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs.
A whiff of plasma, when combined with a nanosized catalyst, can cause chemical reactions to proceed faster, more selectively, at lower temperatures, or at lower voltages than without plasma. Using computer modeling, researchers investigated the interactions between plasmas and metal catalysts embedded into ceramic beads in a packed bed reactor. They discovered that together, the metals, beads and
A bleached fringe of dead marine algae, strung along the coastlines of two islands off the coast of Chile, offers a unique glimpse at how the land rose during the 2016 magnitude 7.6 Chiloé earthquake, according to a new study.
Hypotrichosis simplex leads to progressive hair loss starting in childhood. Geneticists have now deciphered a new gene that is responsible for this rare form of hair loss. Changes in the LSS gene lead to impairment of an important enzyme that has a crucial function in cholesterol metabolism.
Scientists have discovered the inner workings of a known 'speed gene', which directly affects skeletal muscle growth and, in turn, race distance aptitude in thoroughbred racehorses. Their findings have important implications for a multi-billion dollar industry.
The number of overdose deaths involving methamphetamines and amphetamines in the state of Ohio increased more than 5,000 percent over the course of eight years, according to data collected by the Ohio Alliance for Innovation in Population Health.
A new immunotherapy screening prototype developed by University of California, Irvine researchers can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs.
Adolescent marijuana use may alter how neurons function in brain areas engaged in decision-making, planning and self-control, according to researchers.
In 1811 and 1812, the region around New Madrid, Missouri, experienced a number of major earthquakes. The final and largest earthquake in this sequence occurred on the Reelfoot fault, and temporarily changed the course of the Mississippi River.
Many of today's methods of purifying water rely on filters and chemicals that need regular replenishing or maintenance. Millions of people, however, live in areas with limited access to such materials, leading the research community to explore new options of purifying water in using plasmas. Many plasma-based approaches are expensive, but a new class of plasma devices may change that. Researchers
STOP! This is illegal. You may be monitored and fined. Did that get your attention? Good. Because according to a new study, this phrasing coupled with a graphic of a computer and download symbol with a prohibitive slash is the most effective way to stop music piracy.
Landfill gases contain numerous contaminants, but one group has demonstrated a promising new application of plasma technology capable of removing such compounds. Researchers have demonstrated an experimental plasma device capable of cleaning gas samples of D4, one of the most common siloxanes. Drawing on a technique for creating plasma called dielectric barrier discharge, the group was able to sig
Research released today underscores both the dangers and the therapeutic promise of marijuana, revealing different effects across the lifespan. Marijuana exposure in the womb or during adolescence may disrupt learning and memory, damage communication between brain regions, and disturb levels of key neurotransmitters and metabolites in the brain. In Alzheimer's disease, however, compounds found in
Scars left by orca attacks indicate that most victims are young whales on the first trip from breeding to feeding grounds. Increasing numbers of scars may mean that there are more orcas in the Southern Pacific, researchers say.
A team of oceanographers has journeyed to Norway — one of the last remaining regions of the world where cod still thrive — and used a synoptic acoustic system to, for the first time, illuminate entire shoals of cod almost instantaneously, during the height of the spawning season.
Researchers have singled out a protein called TIM-3 as a new potential target for immunotherapy treatments for patients with cancer and other diseases. Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. The new study sheds light on a molecule that might play a key role in the regulation of the immune response
In a Veterans Affairs study, a manmade compound based on a brain hormone spurred the growth of cancer in Petri dishes but enigmatically had the opposite effect in mice. The compound and others like it are being looked at not only for their effect on cancer, but for their ability to regrow healthy tissue to heal damaged hearts and other organs.
For the most part, the mature Atlantic cod is a solitary creature that spends most of its time far below the ocean's surface, grazing on bony fish, squid, crab, shrimp, and lobster—unless it's spawning season, when the fish flock to each other by the millions, forming enormous shoals that resemble frenzied, teeming islands in the sea.
Humpback whales bear stark battle scars from violent encounters with orcas, also known as killer whales. Analysis of rake marks on more than 3000 humpback whale tails or flukes suggest that attacks on these undersea giants may be on the rise, according to a new study in Endangered Species Research.
As Tropical Storm Xavier continued to rain on western Mexico, the Global Precipitation Measurement mission or GPM core satellite analyzed the rate in which rain was falling. The next day, Nov, 6, Xavier had weakened to a remnant low pressure area.
Moths are a mainstay food source for bats, which use echolocation (biological sonar) to hunt their prey. Scientists such as Thomas Neil, from the University of Bristol in the U.K., are studying how moths have evolved passive defenses over millions of years to resist their primary predators.
A bleached fringe of dead marine algae, strung along the coastlines of two islands off the coast of Chile, offers a unique glimpse at how the land rose during the 2016 magnitude 7.6 Chiloé earthquake, according to a new study in the Bulletin of the Seismological Society of America.
A team of oceanographers at MIT has journeyed to Norway — one of the last remaining regions of the world where cod still thrive — and used a synoptic acoustic system to, for the first time, illuminate entire shoals of cod almost instantaneously, during the height of the spawning season.
The latest research on low calorie sweeteners' use, benefits and role in the diet were discussed today at the 3rd International Sweeteners Association Conference.
Scars left by orca attacks indicate that most victims are young whales on the first trip from breeding to feeding grounds. Increasing numbers of scars may mean that there are more orcas in the Southern Pacific, researchers say.
As Tropical Storm Xavier continued to rain on western Mexico, the Global Precipitation Measurement mission or GPM core satellite analyzed the rate in which rain was falling. The next day, Nov. 6, Xavier had weakened to a remnant low pressure area.
Adolescent marijuana use may alter how neurons function in brain areas engaged in decision-making, planning and self-control, according to researchers at the University of Illinois at Chicago.
Many of today's methods of purifying water rely on filters and chemicals that need regular replenishing or maintenance. Millions of people, however, live in areas with limited access to such materials, leading the research community to explore new options of purifying water in using plasmas. Many plasma-based approaches are expensive, but a new class of plasma devices may change that.
Zero-deforestation commitments within the palm oil industry risk being undermined by a lack of monitoring within production landscapes—meaning the deforestation of tropical forests home to Critically Endangered wildlife such as Sumatran tigers (Panthera tigris sumatrae) and orangutans (Pongo abelii) could be going unreported. This is just one finding of an in-depth evaluation of palm oil companies
Botanists at the University of Washington's Burke Museum of Natural History & Culture have created a much-needed second edition of the "Flora of the Pacific Northwest." Published by the UW Press, the new edition took five years to complete and is the first update on Pacific Northwest vascular plant diversity and distributions since the book was first published in 1973. In the past 45 years, much h
How ideas move through academia may depend on where those ideas come from—whether from big-name universities or less prestigious institutions—as much as their quality, a recent study from the University of Colorado Boulder suggests.
Methane gas released from landfills has long been a topic of interest for alternative energy. One issue, however, is that landfill gases contain numerous contaminants, such as volatile methyl siloxanes, whose silica deposits put extra wear and tear on the natural gas generators when they combust. One group has demonstrated a promising new application of plasma technology capable of removing such c
In 1811 and 1812, the region around New Madrid, Missouri, experienced a number of major earthquakes. The final and largest earthquake in this sequence occurred on the Reelfoot fault, and temporarily changed the course of the Mississippi River. These earthquakes are estimated to be just shy of magnitude 8.0 and devastated towns along the Mississippi River—soil liquefied, houses collapsed, and chimn
A whiff of plasma, when combined with a nanosized catalyst, can cause chemical reactions to proceed faster, more selectively, at lower temperatures, or at lower voltages than without plasma—and nobody really knows why.
Researchers have invented a liquid isomer that can store and release solar energy. The team has solved problems other researchers have previously encountered. The discovery could lead to more widespread use of solar energy. In the last year, a team from Chalmers University of Technology , Sweden, essentially figured out how to bottle solar energy . They developed a liquid fuel containing the comp
Lorenzi et al. (1) recently applied a functional prioritization method to the Alzheimer’s Disease Neuroimaging Initiative dataset and successfully identified a link between tribbles pseudokinase 3 (TRIB3) and the stereotypical pattern of gray matter loss in Alzheimer’s disease (AD). Lorenzi et al. conducted an expression quantitative trait loci (eQTL) analysis…
Nosek et al. (1) recently joined others in advocating for “widespread adoption of preregistration” as a tool for advancing science. The language they use in making this important argument, however, creates unnecessary confusion: Like many others discussing these issues, they seem to conflate the goal of theory falsification with the…
Ledgerwood (1) argues that there are two independent uses of preregistration that are conflated in Nosek et al. (2) and elsewhere: “Preregistering theoretical predictions enables theory falsifiability. Preregistering analysis plans enables type I error control.” We appreciate that the comment elevates the complementary roles of prediction and analysis plans in…
Recent spectroscopic, kinetic, photophysical, and thermodynamic measurements show activation of nitrogenase for N2 → 2NH3 reduction involves the reductive elimination (re) of H2 from two [Fe–H–Fe] bridging hydrides bound to the catalytic [7Fe–9S–Mo–C–homocitrate] FeMo-cofactor (FeMo-co). These studies rationalize the Lowe–Thorneley kinetic scheme’s proposal of mechanistically obligatory formation
Many biological systems rely on the ability to self-assemble different target structures using the same set of components. Equilibrium self-assembly suffers from a limited capacity in such cases, due to an increasing number of decoy states that grows rapidly with the number of targets encoded. Moreover, improving the kinetic stability…
The initiation of intestinal inflammation involves complex intercellular cross-talk of inflammatory cells, including the epithelial and immune cells, and the gut microbiome. This multicellular complexity has hampered the identification of the trigger that orchestrates the onset of intestinal inflammation. To identify the initiator of inflammatory host–microbiome cross-talk, we leveraged a…
Parasites of the phylum Apicomplexa are responsible for significant morbidity and mortality on a global scale. Central to the virulence of these pathogens are the phylum-specific, unconventional class XIV myosins that power the essential processes of parasite motility and host cell invasion. Notably, class XIV myosins differ from human myosins…
Calmodulin (CaM) represents one of the most conserved proteins among eukaryotes and is known to bind and modulate more than a 100 targets. Recently, several disease-associated mutations have been identified in the CALM genes that are causative of severe cardiac arrhythmia syndromes. Although several mutations have been shown to affect…
Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the postsynaptic central nociceptive neurons. The CaV2.2 channel is composed of a pore-forming α1 subunit (CaVα1) that is engaged…
Dephosphorylation of the inhibitory “S259” site on RAF kinases (S259 on CRAF, S365 on BRAF) plays a key role in RAF activation. The MRAS GTPase, a close relative of RAS oncoproteins, interacts with SHOC2 and protein phosphatase 1 (PP1) to form a heterotrimeric holoenzyme that dephosphorylates this S259 RAF site….
We have developed Differential Specificity and Energy Landscape (DiSEL) analysis to comprehensively compare DNA–protein interactomes (DPIs) obtained by high-throughput experimental platforms and cutting edge computational methods. While high-affinity DNA binding sites are identified by most methods, DiSEL uncovered nuanced sequence preferences displayed by homologous transcription factors. Pairwis
The Escherichia coli methionine ABC transporter MetNI exhibits both high-affinity transport toward l-methionine and broad specificity toward methionine derivatives, including d-methionine. In this work, we characterize the transport of d-methionine derivatives by the MetNI transporter. Unexpectedly, the N229A substrate-binding deficient variant of the cognate binding protein MetQ was found to…
Hox5 genes (Hoxa5, Hoxb5, Hoxc5) are exclusively expressed in the lung mesenchyme during embryogenesis, and the most severe phenotypes result from constitutive loss of function of all three genes. Because Hox5 triple null mutants exhibit perinatal lethality, the contribution of this paralogous group to postembryonic lung development is unknown. Intriguingly,…
Codevelopment of the lungs and heart underlies key evolutionary innovations in the transition to terrestrial life. Cardiac specializations that support pulmonary circulation, including the atrial septum, are generated by second heart field (SHF) cardiopulmonary progenitors (CPPs). It has been presumed that transcription factors required in the SHF for cardiac septation,…
Israel experienced an outbreak of wild poliovirus type 1 (WPV1) in 2013–2014, detected through environmental surveillance of the sewage system. No cases of acute flaccid paralysis were reported, and the epidemic subsided after a bivalent oral polio vaccination (bOPV) campaign. As we approach global eradication, polio will increasingly be detected…
Although many cases of genetic adaptations to high elevations have been reported, the processes driving these modifications and the pace of their evolution remain unclear. Many high-elevation adaptations (HEAs) are thought to have arisen in situ as populations rose with growing mountains. In contrast, most high-elevation lineages of the Qinghai-Tibetan…
Women having BRCA1 germ-line mutations develop cancer in breast and ovary, estrogen-regulated tissues, with high penetrance. Binding of estrogens to the estrogen receptor (ER) transiently induces DNA double-strand breaks (DSBs) by topoisomerase II (TOP2) and controls gene transcription. TOP2 resolves catenated DNA by transiently generating DSBs, TOP2-cleavage complexes (TOP2ccs), where…
The carboxy-terminal domain (CTD) code encrypted within the Y1S2P3T4S5P6S7 heptad repeats of RNA polymerase II (Pol2) is deeply rooted in eukaryal biology. Key steps to deciphering the code are identifying the events in gene expression that are governed by individual “letters” and then defining a vocabulary of multiletter “words” and…
Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes a range of diseases, including fatal invasive infections. However, the mechanisms by which the innate immune system recognizes GAS are not well understood. We herein report that the C-type lectin receptor macrophage inducible C-type lectin (Mincle) recognizes GAS and…
FoxP3+ T regulatory (Treg) cells are central elements of immunologic tolerance. They are abundant in many tumors, where they restrict potentially favorable antitumor responses. We used a three-pronged strategy to identify genes related to the presence and function of Tregs in the tumor microenvironment. Gene expression profiles were generated from…
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by low platelet count which can cause fatal hemorrhage. ITP patients with antiplatelet glycoprotein (GP) Ib-IX autoantibodies appear refractory to conventional treatments, and the mechanism remains elusive. Here we show that the platelets undergo apoptosis in ITP patients with anti-GPIbα autoantibodies. Consistent…
Extracellular vesicles (EVs) have been implicated in the development and progression of hematological malignancies. We thus examined serum samples from patients with systemic mastocytosis (SM) and found EVs with a mast cell signature including the presence of tryptase, FcεRI, MRGX2, and KIT. The concentration of these EVs correlated with parameters…
Tumor-specific T cell receptor (TCR) gene transfer enables specific and potent immune targeting of tumor antigens. Due to the prevalence of the HLA-A2 MHC class I supertype in most human populations, the majority of TCR gene therapy trials targeting public antigens have employed HLA-A2–restricted TCRs, limiting this approach to those…
The gut metabolic landscape is complex and is influenced by the microbiota, host physiology, and enteric pathogens. Pathogens have to exquisitely monitor the biogeography of the gastrointestinal tract to find a suitable niche for colonization. To dissect the important metabolic pathways that influence virulence of enterohemorrhagic Escherichia coli (EHEC), we…
Adequate pain management remains an unmet medical need. We previously revealed an opioid-independent analgesic mechanism mediated by orexin 1 receptor (OX1R)-initiated 2-arachidonoylglycerol (2-AG) signaling in the ventrolateral periaqueductal gray (vlPAG). Here, we found that low-frequency median nerve stimulation (MNS) through acupuncture needles at the PC6 (Neiguan) acupoint (MNS-PC6) induced a
Impulsivity is closely associated with addictive disorders, and changes in the brain dopamine system have been proposed to affect impulse control in reward-related behaviors. However, the central neural pathways through which the dopamine system controls impulsive behavior are still unclear. We found that the absence of the D2 dopamine receptor…
Orexin (also known as hypocretin) neurons in the hypothalamus play an essential role in sleep–wake control, feeding, reward, and energy homeostasis. The likelihood of anesthesia and sleep sharing common pathways notwithstanding, it is important to understand the processes underlying emergence from anesthesia. In this study, we investigated the role of…
Neurodegenerative disorders, such as Huntington’s diseases and spinocerebellar ataxias (SCAs), are driven by proteins with expanded polyglutamine (polyQ) tracts. Recently, coiled-coil structures in polyQ regions of such proteins were shown to facilitate aggregate formation and ultimately lead to cell death. However, the molecular mechanism linking these structural domains to neuronal…
Conditions of metabolic distress, from malnutrition to obesity, impact, via as yet ill-defined mechanisms, the timing of puberty, whose alterations can hamper later cardiometabolic health and even life expectancy. AMP-activated protein kinase (AMPK), the master cellular energy sensor activated in conditions of energy insufficiency, has a major central role in…
Plant immune responses mediated by the hormone jasmonoyl-l-isoleucine (JA-Ile) are metabolically costly and often linked to reduced growth. Although it is known that JA-Ile activates defense responses by triggering the degradation of JASMONATE ZIM DOMAIN (JAZ) transcriptional repressor proteins, expansion of the JAZ gene family in vascular plants has hampered…
Matching ATP:NADPH provision and consumption in the chloroplast is a prerequisite for efficient photosynthesis. In terms of ATP:NADPH ratio, the amount of ATP generated from the linear electron flow does not meet the demand of the Calvin–Benson–Bassham (CBB) cycle. Several different mechanisms to increase ATP availability have evolved, including cyclic…
Protected areas (PAs) play an important role in conserving biodiversity and providing ecosystem services, yet their effectiveness is undermined by funding shortfalls. Using lions (Panthera leo) as a proxy for PA health, we assessed available funding relative to budget requirements for PAs in Africa’s savannahs. We compiled a dataset of…
Most organisms must cope with temperature changes. This involves genes and gene networks both as subjects and agents of cellular protection, creating difficulties in understanding. Here, we study how heating and cooling affect expression of single genes and synthetic gene circuits in Saccharomyces cerevisiae. We discovered that nonoptimal temperatures induce…
The host factor protein TRIM5α plays an important role in restricting the host range of HIV-1, interfering with the integrity of the HIV-1 capsid. TRIM5 triggers an antiviral innate immune response by functioning as a capsid pattern recognition receptor, although the precise mechanism by which the restriction is imposed is…
An immense repertoire of protein chemical modifications catalyzed by enzymes is available as proteomics data. Quantifying the impact of the conformational dynamics of the modified peptide remains challenging to understand the decisive kinetics and amino acid sequence specificity of these enzymatic reactions in vivo, because the target peptide must be…
Recent experiments have shown that mouse primary visual cortex (V1) is very different from that of cat or monkey, including response properties—one of which is that contrast invariance in the orientation selectivity (OS) of the neurons’ firing rates is replaced in mouse with contrast-dependent sharpening (broadening) of OS in excitatory…
The activation of the epidermal growth factor receptor (EGFR) is crucial for triggering diverse cellular functions, including cell proliferation, migration, and differentiation, and up-regulation of EGFR expression or activity is a key factor in triggering the development of cancer. Here we show that overexpression of a scaffold protein, tumor necrosis…
During invasion, cells breach basement membrane (BM) barriers with actin-rich protrusions. It remains unclear, however, whether actin polymerization applies pushing forces to help break through BM, or whether actin filaments play a passive role as scaffolding for targeting invasive machinery. Here, using the developmental event of anchor cell (AC) invasion…
Suspected fractures are among the most common reasons for patients to visit emergency departments (EDs), and X-ray imaging is the primary diagnostic tool used by clinicians to assess patients for fractures. Missing a fracture in a radiograph often has severe consequences for patients, resulting in delayed treatment and poor recovery…
Human-dominated landscapes represent one of the most rapidly expanding and least-understood ecosystems on earth. Yet, we know little about which features in these landscapes promote sustainable wildlife populations. Historically, in urban areas, landowners have converted native plant communities into habitats dominated by nonnative species that are not susceptible to pest…
Determination of long-term tropical cyclone (TC) variability is of enormous importance to society; however, changes in TC activity are poorly understood owing to discrepancies among various datasets and limited span of instrumental records. While the increasing intensity and frequency of TCs have been previously documented on a long-term scale using…
We describe a specimen of the basal ornithuromorph Archaeorhynchus spathula from the Lower Cretaceous Jiufotang Formation with extensive soft tissue preservation. Although it is the fifth specimen to be described, unlike the others it preserves significant traces of the plumage, revealing a pintail morphology previously unrecognized among Mesozoic birds, but…
In polyandrous species, fathers benefit from attracting greater maternal investment toward their offspring at the expense of the offspring of other males, while mothers should usually allocate resources equally among offspring. This conflict can lead to an evolutionary arms race between the sexes, manifested through antagonistic genes whose expression in…
Whole-exome sequencing has been successful in identifying genetic factors contributing to familial or sporadic Parkinson’s disease (PD). However, this approach has not been applied to explore the impact of de novo mutations on PD pathogenesis. Here, we sequenced the exomes of 39 early onset patients, their parents, and 20 unaffected…
Invasive microbes causing diseases such as sudden oak death negatively affect ecosystems and economies around the world. The deployment of resistant genotypes for combating introduced diseases typically relies on breeding programs that can take decades to complete. To demonstrate how this process can be accelerated, we employed a genome-wide association…
Adaptive natural killer (NK) cell memory represents a new frontier in immunology. Work over the last decade has discovered and confirmed the existence of NK cells with antigen-specific memories, which had previously been considered a unique property of T and B cells. These findings have shown that antigen-specific NK cells…
The cytokine IFN-γ is a critical regulator of immune system development and function. Almost all leukocytes express the receptor for IFN-γ, yet each cell type elicits a different response to this cytokine. Cell type-specific effects of IFN-γ make it difficult to predict the outcomes of the systemic IFN-γ blockade and…
Receptor-type protein tyrosine phosphatase D (PTPRD) is a neuronal cell-adhesion molecule/synaptic specifier that has been implicated in addiction vulnerability and stimulant reward by human genomewide association and mouse cocaine-conditioned place-preference data. However, there have been no reports of effects of reduced expression on cocaine self-administration. There have been no reports…
Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes immunosuppression, paralysis, and deadly lymphomas in chickens. In infected animals, B cells are efficiently infected and are thought to amplify the virus and transfer it to T cells. MDV subsequently establishes latency in T cells and transforms CD4+ T…
Flaviviruses assemble initially in an immature, noninfectious state and undergo extensive conformational rearrangements to generate mature virus. Previous cryo-electron microscopy (cryo-EM) structural studies of flaviviruses assumed icosahedral symmetry and showed the concentric organization of the external glycoprotein shell, the lipid membrane, and the internal nucleocapsid core. We show here th
Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical trials and laboratory studies of favipiravir have not yielded resistant viruses. Here we show evolution of resistance to favipiravir in the…
Increasing age is the greatest known risk factor for the sporadic late-onset forms of neurodegenerative disorders such as Alzheimer’s disease (AD). One of the brain regions most severely affected in AD is the hippocampus, a privileged structure that contains adult neural stem cells (NSCs) with neurogenic capacity. Hippocampal neurogenesis decreases…
CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) and DE-ETIOLATED 1 (DET1) are founding components of two central repressor complexes of photomorphogenesis that trigger the degradation of a larger number of photomorphogenic-promoting factors in darkness. Here, we identify COP1 SUPPRESSOR 4 (CSU4) as a genetic suppressor of the cop1-6 mutation. Mutations in CSU4 largely…
The structurally conserved but sequence-unrelated MAX (Magnaporthe oryzae avirulence and ToxB-like) effectors AVR1-CO39 and AVR-PikD from the blast fungus M. oryzae are recognized by the rice nucleotide-binding domain and leucine-rich repeat proteins (NLRs) RGA5 and Pikp-1, respectively. This involves, in both cases, direct interaction of the effector with a heavy…
The circadian clock orchestrates 24-h rhythms in physiology in most living organisms. At the molecular level, the dogma is that circadian oscillations are based on a negative transcriptional feedback loop. Recent studies found the NAD+-dependent histone deacetylase, SIRT1, directly regulates acetylation status of clock components and influences circadian amplitude in…
BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “Biophysical and functional characterization of Norrin signaling through Frizzled4,” by Injin Bang, Hee Ryung Kim, Andrew H. Beaven, Jinuk Kim, Seung-Bum Ko, Gyu Rie Lee, Hasup Lee, Wonpil Im, Chaok Seok, Ka Young Chung, and Hee-Jung Choi, which was first published August 13, 2018;…
Shifting tropical cyclone hazards Uprooted trees in Hallasan National Park, South Korea, after Typhoon Bolaven struck in August 2012. The long-term variability of tropical cyclone (TC) activity is unclear, largely due to discrepancies among data sets and brief instrumental records. Jan Altman et al. (pp. 11543–11548) estimated the long-term variability…
Developmental social psychology has been in turmoil since 2005, when the first study using implicit, nonverbal measures with preverbal infants appeared to show that they could attribute false beliefs to other agents, forming expectations about an agent’s behavior on that basis (1). This was an exciting finding, suggesting that core…
During development, seeds compete, directly or indirectly, for access to resources supplied by the maternal plant. This competition is expected to be more intense when embryos (and associated endosperms) are less related to each other because they are fertilized by less-related pollen (1). Imprinted genes of paternal origin in offspring…
Traditional teaching in immunology tells us that antigen-specific recall responses are the realm of adaptive immunity. However, over the past decade, there has been increasing evidence and interest in the concept of innate immune memory. Natural killer (NK) cells are the founding member of the innate lymphocyte family, initially recognized…
Pork accounts for more than one-third of meat produced worldwide and is an important component of global food security, agricultural economies, and trade. Infectious diseases are among the primary constraints to swine production, and the globalization of the swine industry has contributed to the emergence and spread of pathogens. Despite…
The first part of this paper reviews the basic tenets of attachment theory with respect to differences in cultural socialization strategies. In one strategy infants have the lead, and the social environment is responsive to the infant’s wishes and preferences. In another strategy the caregivers—children or adults—are experts who know…
The many tools that social and behavioral scientists use to gather data from their fellow humans have, in most cases, been honed on a rarefied subset of humanity: highly educated participants with unique capacities, experiences, motivations, and social expectations. Through this honing process, researchers have developed protocols that extract information…
Natural selection, developmental constraint, and plasticity have all been invoked as explanations for intraspecific cranial variation in humans and apes. However, global patterns of human cranial variation are congruent with patterns of genetic variation, demonstrating that population history has influenced cranial variation in humans. Here we show that this finding…
Bioimaging plays an important role in cancer diagnosis and treatment. However, imaging sensitivity and specificity still constitute key challenges. Nanotechnology-based imaging is particularly promising for overcoming these limitations because nanosized imaging agents can specifically home in on tumors via the “enhanced permeation and retention” (EPR) effect, thus resulting in enhanced…
The 3D spatiotemporal organization of the human genome inside the cell nucleus remains a major open question in cellular biology. In the time between two cell divisions, chromatin—the functional form of DNA in cells—fills the nucleus in its uncondensed polymeric form. Recent in vivo imaging experiments reveal that the chromatin…
RNA virus genomes are efficient and compact carriers of biological information, encoding information required for replication both in their primary sequences and in higher-order RNA structures. However, the ubiquity of RNA elements with higher-order folds—in which helices pack together to form complex 3D structures—and the extent to which these elements…
Many natural silks produced by spiders and insects are unique materials in their exceptional toughness and tensile strength, while being lightweight and biodegradable–properties that are currently unparalleled in synthetic materials. Myriad approaches have been attempted to prepare artificial silks from recombinant spider silk spidroins but have each failed to achieve…
A robotic lander surveys a frosty landscape near the northern pole of Mars sometime in the 2020s. Revving up a powerful 1-meter drill, it bores into the polar subsurface, extracts a sample, and runs it through a battery of cleverly designed instruments. Maybe, just maybe, it uncovers the chemical residues…
Predicting North Atlantic hurricane activity months in advance is of great potential societal significance. The ocean temperature, both in terms of North Atlantic/tropical averages and upper ocean heat content, is demonstrated to be a significant predictor. To investigate the relationship between the thermal state of the Atlantic Ocean and the…
Global climate models robustly predict that global mean precipitation should increase at roughly 2–3% K−1, but the origin of these values is not well understood. Here we develop a simple theory to help explain these values. This theory combines the well-known radiative constraint on precipitation, which says that condensation heating…
Demand for traditional medicine ingredients is causing species declines globally. Due to this trade, Himalayan caterpillar fungus (Ophiocordyceps sinensis) has become one of the world’s most valuable biological commodities, providing a crucial source of income for hundreds of thousands of collectors. However, the resulting harvesting boom has generated widespread concern…
We report experimental findings on how individuals from different cultures solve a repeated coordination game of common interest. The results overturn earlier findings that fixed pairs are almost assured to coordinate on an efficient and cooperative equilibrium. Subjects in the prior experiments were US university students, whereas the subjects in…
The development and deployment of matching procedures that incentivize truthful preference reporting is considered one of the major successes of market design research. In this study, we test the degree to which these procedures succeed in eliminating preference misrepresentation. We administered an online experiment to 1,714 medical students immediately after…
Microbial populations often assemble in dense populations in which proliferating individuals exert mechanical forces on the nearby cells. Here, we use yeast strains whose doubling times depend differently on temperature to show that physical interactions among cells affect the competition between different genotypes in growing yeast colonies. Our experiments demonstrate…
Understanding intraspecific variation in sociality is essential for characterizing the flexibility and evolution of social systems, yet its study in nonhuman animals is rare. Here, we investigated whether chimpanzees exhibit population-level differences in sociality that cannot be easily explained by differences in genetics or ecology. We compared social proximity and…
The present lack of sample diversity and ecological theory in psychological science fundamentally limits generalizability and obstructs scientific progress. A focus on the role of socioecology in shaping the evolution of morphology, physiology, and behavior has not yet been widely applied toward psychology. To date, evolutionary approaches to psychology have…
Extreme biased sampling of research participants and the neglect of their cultural context are increasingly recognized as threats to the generalizability of much of what we know about human thought and behavior (1, 2). In addition to reinforcing narrow views of what it means to be human, these parochial research…
Is there a universal hierarchy of the senses, such that some senses (e.g., vision) are more accessible to consciousness and linguistic description than others (e.g., smell)? The long-standing presumption in Western thought has been that vision and audition are more objective than the other senses, serving as the basis of…
In light of calls for improving people’s skill in collaboration, this paper examines strengths in processes of collaboration of Mexican immigrant children. Sibling pairs (6–10 years old) in California were asked to collaborate in planning the shortest route through a model grocery store. On average, 14 sibling pairs with Mexican…
Two primary goals of psychological science should be to understand what aspects of human psychology are universal and the way that context and culture produce variability. This requires that we take into account the importance of culture and context in the way that we write our papers and in the…
A lack of interpretive power (i.e., the ability to understand individuals’ experiences and behaviors in relation to their cultural contexts) undermines psychology’s understanding of diverse psychological phenomena. Building interpretive power requires attending to cultural influences in research. We describe three characteristics of research that lacks interpretive power: normalizing and overgener
This commentary focuses on two important contrasts in the behavioral sciences: (i) default versus nondefault study populations, where default samples have been used disproportionately (for psychology, the default is undergraduates at major research universities), and (ii) the adoption of a distant versus close (engaged) attitude toward study samples. Previous research…
A current debate in psychology and cognitive science concerns the nature of young children’s ability to attribute and track others’ beliefs. Beliefs can be attributed in at least two different ways: prospectively, during the observation of belief-inducing situations, and in a retrospective manner, based on episodic retrieval of the details…
The successful integration of immigrants into a host country’s society, economy, and polity has become a major issue for policymakers in recent decades. Scientific progress in the study of immigrant integration has been hampered by the lack of a common measure of integration, which would allow for the accumulation of…
Health Nothing about the combination of stimulants inside Monster and Red Bull is healthy, and some of it is actively harmful. Energy drinks aren’t food. They’re classified as supplements, which means they’re unregulated and free to have as much caffeine as manufacturers want to shove inside a…
Russia's space agency says that one of the International Space Station's computers has malfunctioned, but the glitch doesn't pose any risks to the crew.
Senegal on Tuesday inaugurated a cyber-security school to strengthen West Africa's defences against computer hackers and use of the internet for terror funding and propaganda.
'Oumuamua is an oddly shaped, puzzling celestial object because it doesn't act like anything naturally occurring. The issue? The unexpected way it accelerated near the Sun. Is this our first sign of extraterrestrials? It's pronounced: oh MOO-uh MOO-uh. That odd-shaped visitor from beyond our solar system, 'Oumuamua (Hawaiian for "scout"), has been fascinating from the moment it arrived: It's a sp
Research released today underscores both the dangers and the therapeutic promise of marijuana, revealing different effects across the lifespan. Marijuana exposure in the womb or during adolescence may disrupt learning and memory, damage communication between brain regions, and disturb levels of key neurotransmitters and metabolites in the brain. In Alzheimer's disease, however, compounds found in
Landfill gases contain numerous contaminants, but one group has demonstrated a promising new application of plasma technology capable of removing such compounds. Researchers have demonstrated an experimental plasma device capable of cleaning gas samples of D4, one of the most common siloxanes. Drawing on a technique for creating plasma called dielectric barrier discharge, the group was able to sig
Many of today's methods of purifying water rely on filters and chemicals that need regular replenishing or maintenance. Millions of people, however, live in areas with limited access to such materials, leading the research community to explore new options of purifying water in using plasmas. Many plasma-based approaches are expensive, but a new class of plasma devices may change that. Researchers
The American College of Cardiology, the American Heart Association and the Heart Rhythm Society today released a guideline for the evaluation and treatment of patients with bradycardia, or a slow heartbeat, and cardiac conduction disorders.
Moths are a mainstay food source for bats, which use echolocation to hunt their prey. Scientists are studying how moths have evolved passive defenses over millions of years to resist their primary predators. While some moths have evolved ears that detect the ultrasonic calls of bats, many types of moths remain deaf. In those moths, researchers have found that the insects developed types of 'stealt
This week, PLOS Medicine launches our Special Issue on Machine Learning in Health and Biomedicine, Guest Edited by Atul Butte of the Institute for Computational Health Sciences at UCSF, Suchi Saria of the Department of Computer Science, Statistics, and Health Policy at Johns Hopkins University and the Malone Center for Engineering in Healthcare, and Aziz Sheikh of the Usher Institute of Population
STOP! This is illegal. You may be monitored and fined. Did that get your attention? Good. Because according to a new UNLV study, this phrasing coupled with a graphic of a computer and download symbol with a prohibitive slash is the most effective way to stop music piracy.
TUCSON, Ariz.—The great myth of America’s participatory democracy is that people actually participate. In the 2016 election—the controversial, generation-defining 2016 election—61 percent of voting-age citizens cast a ballot, according to census data. And that was a presidential year. The last time America held midterm elections, 42 percent of voting-age citizens participated. This has been the t
The Georgia governor’s race is balanced on a knife’s edge. Local polls have the Democratic nominee Stacey Abrams and her GOP opponent, Georgia Secretary of State Brian Kemp, virtually tied . Abrams’s team in particular will scramble to make sure every provisional ballot is completed, that every person who faced challenges to registration is able to participate, that all absentee and vote-by-mail
High levels of human-made CO 2 causes ocean acidification that is rapidly dissolving the seafloor, a new study warns. Normally the deep sea bottom is a chalky white. It’s composed, to a large extent, of the mineral calcite (CaCO 3 ) formed from the skeletons and shells of many planktonic organisms and corals. The seafloor plays a crucial role in controlling the degree of ocean acidification. The
Researchers studied 28 middle school and high school students 12 to 19 years old who are youth caregivers for sick family members. The study is the first of its kind to take a comprehensive look at this population.
The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, a new study indicates.
To break out of Earth's lower orbit, hypersonic vehicles must reach speeds greater than Mach 5. At these hypersonic speeds, the air particles and gases that flow around the vehicle and interact with the surfaces generate heat and create shock waves that disturb the flow's equilibrium. Researchers created a model to simulate and better understand flow transitions.
A widely used naloxone nasal spray (NNS) and naloxone injection (NIJ), otherwise known as Narcan® and Evzio®, which are administered to prevent opioid overdose deaths, were found to be chemically stable up for at least ten months and beyond one year of the expiration date, respectively.
Researchers have identified a novel protein secreted by a common gut bacterium in zebrafish that reduces inflammation in the gut and delays death by septic shock.
Advances in connecting neural stimulation to physical control of the body are transforming the development of prosthetics and therapeutic training for people with disabilities, according to new research.
Asian jumping earthworms are carving out territory all over the US Midwest and East Coast, leaving in their wake changed soils that are just beginning to be studied.
Researchers have introduced a new, simple measure for human wellbeing across countries, called the Human Life Indicator (HLI), that takes inequality into account and could replace the commonly used but error-prone Human Development Index (HDI).
In 1811 and 1812, the region around New Madrid, Mo., experienced a number of major earthquakes. The final and largest earthquake in this sequence occurred on the Reelfoot fault, and temporarily changed the course of the Mississippi River.
A legal battle between a maritime salvage company and the state of Florida could have implications for some of the oldest European artifacts in the U.S.
A drug screen using the SPECTRUM library identified candidates that restore energy production in DGUOK-deficient liver-like cells, offering the first potential treatment for MTDPS.
People younger than age 40 who have high blood pressure are at increased risk of heart failure, strokes and blood vessel blockages as they age, according to a new study.
Pictures may be worth a thousand words, but icons may be even more powerful in nudging people to disclose more information online, according to an interdisciplinary team.
Researchers found that frequent, persistent back pain is associated with earlier death in a study of more than 8,000 older women who were followed for an average of 14 years.
Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. Chemists have developed a new synthetic approach that allows RNA to be chemically synthesized about a million times more efficiently than previously possible.
Lack of varied seasons and temperatures in tropical mountains have led to species that are highly adapted to their narrow niches, creating the right conditions for new species to arise in these areas, according to a new study. Still, the same traits that make tropical mountains among the most biodiverse ecosystems on Earth also make the species that live there more vulnerable to rapid climate chan
A novel computational tool called ADmiRE extensively annotates human microRNA variants to determine which ones are likely to contribute to or cause diseases.
Each state takes a different approach on how it tries to stem the impact of opioid abuse, resulting in significant variation between opioid prescription rates and the number of children placed into foster care.
Five years after one particular tiny thorn snail from Panama was identified as new to science, it is described in a scientific article. The official discovery only became possible after earlier this year glassy shells were collected from the La Amistad International Park, Chiriquí, Panama. Successfully recognized thanks to modern computed tomographic scans, the species adds to the few snails ever
Emerging evidence suggests that emotional vulnerabilities in autism spectrum disorder are already present in the second year of life and are independent of autism symptoms.
A whiff of plasma, when combined with a nanosized catalyst, can cause chemical reactions to proceed faster, more selectively, at lower temperatures, or at lower voltages than without plasma. Using computer modeling, researchers investigated the interactions between plasmas and metal catalysts embedded into ceramic beads in a packed bed reactor. They discovered that together, the metals, beads and
On Monday morning, Sean Hannity, the talk-radio host and the star of the Fox News Channel’s angriest and most watched prime-time show, defended himself in a tweet. “In spite of reports,” Hannity insisted, “I will be doing a live show from Cape Girardeau and interviewing President Trump before the rally. To be clear, I will not be on stage campaigning with the President. I am covering final rally
Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals. The report includes detailed clinical characterization of seven related Amish children who were homozygous for the variant. The children all exhibited poor growth, developmental delay, abnormal brain white matter, hearing los
Risk factors of type 2 diabetes and cardiovascular disease accumulate in children who have poor aerobic fitness, a new study from the University of Eastern Finland shows. The study also found that the traditional way of expressing aerobic fitness in proportion to total body mass overestimates the role of aerobic fitness in identifying children at an increased risk of these diseases.
Ten years of commercial airliner-based measurements uniquely revealed three-dimensional distribution of atmospheric CO2 and its seasonality over Asia Pacific. Asia has been only sparsely monitored for atmospheric CO2, despite the growing importance of the region in the global carbon cycle. The remarkable feature of CO2 over Asia is depleted CO2 concentrations confined in the Asian summer monsoon a
Researchers have developed a new methodical approach. It allows for the faster identification of flavor-giving protein fragments in foods such as cheese or yogurt, thus optimizing production processes.
Sign languages can help reveal hidden aspects of the logical structure of spoken language, but they also highlight its limitations because speech lacks the rich iconic resources that sign language uses on top of its sophisticated grammar.
In a new article, researchers are calling for a rethink on tropical marine conservation efforts, as people who previously relied on coral reefs for food and income are increasingly looking to alternative habitats which is putting pressure on the animals that inhabit seagrass meadows.
Scientists have discovered new details about the UHRF1 protein. UHRF1 catalyses particular steps that are required for marking DNA with epigenetic modifications that suppress parts of the genome. The molecule may serve as a target for drug therapies because it is produced at elevated levels in cancer cells.
An new study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area (EU/EEA). The burden of disease is measured in number of cases, attributable deaths and disability-adjusted life years (DALYs). These estimates are based on data from the European Antimicrobial Resistance Surveillance
Julia Belkowitz, M.D., M.P.H., a University of Miami Miller School of Medicine physician-researcher and pediatrician, and colleagues studied 28 middle school and high school students 12 to 19 years old who are youth caregivers for sick family members. The study is the first of its kind to take a comprehensive look at this population; they reported their findings online in the Journal of Adolescenc
A bleached fringe of dead marine algae, strung along the coastlines of two islands off the coast of Chile, offers a unique glimpse at how the land rose during the 2016 magnitude 7.6 Chiloé earthquake, according to a new study in the Bulletin of the Seismological Society of America.
The phone, called FlexPai, features three screens when folded and it costs $1,318. FlexPai runs Royole's custom Water OS, which will likely be a downside for consumers. Samsung, which has reportedly spent years developing a flexible smartphone, is expected to release a new device this week. A Chinese tech company unveiled the world's first foldable phone to journalists on Monday, a move that come
To break out of Earth's lower orbit, hypersonic vehicles must reach speeds greater than Mach 5. At these hypersonic speeds, the air particles and gases that flow around the vehicle and interact with the surfaces generate heat and create shock waves that disturb the flow's equilibrium. New research at the University of Illinois at Urbana-Champaign created a model to simulate and better understand f
A new study into postnatal depression (PND) found the odds of developing this condition increased by 79 percent when mothers had baby boys compared to baby girls. Overall the researchers identified that women who give birth to males are 71-79% more likely to develop PND. Furthermore, women whose births had complications were 174% more likely to experience PND compared to those women who had no com
Engineers have demonstrated a new material they call 'nanocardboard,' an ultrathin equivalent of corrugated paper cardboard. A square centimeter of nanocardboard weighs less than a thousandth of a gram and can spring back into shape after being bent in half. Nanocardboard's stiffness-to-weight ratio makes it ideal for aerospace and microrobotic applications, where every gram counts.
A whistleblower who claimed data consultancy Cambridge Analytica played a role in obtaining data from Facebook users called Tuesday for greater government regulation of social media and online advertising.
To break out of Earth's lower orbit, hypersonic vehicles must reach speeds greater than Mach 5. At these hypersonic speeds, the air particles and gases that flow around the vehicle and interact with the surfaces generate heat and create shock waves that disturb the flow's equilibrium. New research at the University of Illinois at Urbana-Champaign created a model to simulate and better understand f
A widely used naloxone nasal spray (NNS) and naloxone injection (NIJ), otherwise known as Narcan® and Evzio®, which are administered to prevent opioid overdose deaths, were found to be chemically stable up for at least ten months and beyond one year of the expiration date, respectively. The research, Evaluation of Chemical Stability of Naloxone Products Beyond Their Labeled Expiration Dates, was p
The main trade group for French hotels has sued the home-sharing giant Airbnb, accusing it of unfair competition by "knowingly violating" rules imposed as part of a crackdown in one of the US giant's biggest markets.
Asian jumping earthworms are carving out territory all over the U.S. Midwest and East Coast, leaving in their wake changed soils that are just beginning to be studied.
Researchers at the University of Oregon have identified a novel protein secreted by a common gut bacterium in zebrafish that reduces inflammation in the gut and delays death by septic shock.
An observational technique first proposed more than four decades ago to measure the physical parameters of the corona that determine the formation of the solar wind—the source of disturbances in Earth's upper atmosphere—will be demonstrated for the first time next year. These parameters are the density, temperature, and speed of electrons in the corona.
“The very character of our nation is on the ballot on Tuesday,” Joe Biden, the former vice president, said in his final pitch to voters Monday ahead of the U.S. midterm elections. “The rest of the world is looking.” And the rest of the world is looking. Though the midterms are usually shrugged off by international audiences, who tend to focus more on U.S. presidential contests, this year is diffe
The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, indicates a study led by researchers at Children's National Health System.
Asian jumping earthworms are carving out territory all over the US Midwest and East Coast, leaving in their wake changed soils that are just beginning to be studied.
Advances in connecting neural stimulation to physical control of the body are transforming the development of prosthetics and therapeutic training for people with disabilities, according to new research. The findings were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
Although long life tends to run in families, genetics has far less influence on life span than previously thought, according to a new analysis of more than 400 million people. The results suggest that the heritability of life span is well below past estimates, which failed to account for our tendency to select partners with similar traits to our own.
A research group has studied whether parents' gender preferences and investment in offspring are affected by their status, wealth, education or childhood environment. Instead, parental preferences were best predicted by their sex. These results help to make sense of the often contradictory findings on offspring sex preferences.
Scientists have explained how liquid-like droplets made of proteins and DNA form in vitro. Currently, there is a huge interest in understanding the molecular mechanisms behind the creation of such droplets, as it is linked to some human diseases, such as amyotrophic lateral sclerosis (ALS). The results showed how much the sequence of DNA matters in the formation of such droplets.
The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them. Whether and how the intestinal flora will subsequently recover has been investigated by a research team.
Galaxy evolution can be chaotic and messy, but it seems that streams of cold gas spraying out from the region around supermassive black holes may act to calm the storm.
Insects near waste water could give a platypus or trout half a human dose of antidepressants A platypus living in a creek or stream with waste water could be exposed to 50% of a human daily dose of antidepressants just by eating its normal diet of insects, according to new research. A team of scientists, led by researchers at Monash University, has analysed insects and riparian spiders found in s
Most people don't think of the mighty Tyrannosaurus rex as having the grace of a pirouetting ballerina or the poise of a spinning figure skater, but new research indicates that the dinosaur king was quite good at turning to pounce on prey.
A new method uses an MRI to show how sending an electric impulse to the vagus nerve could successfully correct stomach complications. The technique could lead to more precise treatment that drugs and dietary changes have not been able to accomplish. More than 60 million people in the US suffer from disorders in the gastrointestinal tract that electrical stimulation could cure. “Eventually, by ask
Hypotrichosis simplex leads to progressive hair loss already in childhood. A team of researchers led by human geneticists at the University Hospital of Bonn has now deciphered a new gene that is responsible for this rare form of hair loss. Changes in the LSS gene lead to impairment of an important enzyme that has a crucial function in cholesterol metabolism. The scientists now present their findin
Researchers at the University of Oregon have identified a novel protein secreted by a common gut bacterium in zebrafish that reduces inflammation in the gut and delays death by septic shock.
Four out of six South African rhinos that were transferred to a park in southeast Chad in a bid to revive the endangered species have died, but not from poaching, conservationists say.
A University of Kent study into postnatal depression (PND) found the odds of developing this condition increased by 79 percent when mothers had baby boys compared to baby girls. Overall the researchers identified that women who give birth to males are 71-79 percent more likely to develop PND. Furthermore, women whose births had complications were 174 percent more likely to experience PND compared
European Union authorities say they have cleared Disney's acquisition of Fox's entertainment assets, provided Disney sells off some TV channels it controls in Europe to maintain competition.
Britain's data commissioner on Tuesday called for tougher rules governing the use of personal data by political campaigns around the world, declaring that recent investigations have shown a disturbing disregard for voters and their privacy.
Pictures may be worth a thousand words, but icons may be even more powerful in nudging people to disclose more information online, according to an interdisciplinary team of Penn State researchers.
Lack of varied seasons and temperatures in tropical mountains have led to species that are highly adapted to their narrow niches, creating the right conditions for new species to arise in these areas, according to a new study published in the Proceedings of the National Academy of Sciences.
China unveiled on Tuesday a replica of its first permanently crewed space station, which would replace the international community's orbiting laboratory and symbolises the country's major ambitions beyond Earth.
France said Tuesday it is prepared to delay an EU-wide tax on high-tech giants in order to save a proposal that faces opposition from Ireland and Nordic countries.
Placing a jar of feces on a pedestal next to him, billionaire philanthropist Bill Gates made a plea Tuesday for the safe disposal of human waste as he kicked off a "Reinvented Toilet" Expo in China.
IIASA researchers have introduced a new, simple measure for human wellbeing across countries, called the Human Life Indicator (HLI), that takes inequality into account and could replace the commonly used but error-prone Human Development Index (HDI).
Illinois and New Mexico are among the states that could defy the Trump administration with stricter tailpipe emissions standards — Read more on ScientificAmerican.com
People who experience generalized anxiety disorder (GAD) exhibit excessive anxiety and worry about multiple events or activities most days of the week.
Scientists have pinpointed the genetic basis that explains why some thoroughbred racehorses are better equipped to race over sprint distances and others over longer distances. The Irish scientists, from Trinity College Dublin and UCD, have discovered the inner workings of a known "speed gene", which directly affects skeletal muscle growth and, in turn, race distance aptitude.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
A novel computational tool called ADmiRE extensively annotates human microRNA variants to determine which ones are likely to contribute to or cause diseases.
Observations by ALMA and data from the MUSE spectrograph on ESO's VLT have revealed a colossal fountain of molecular gas powered by a black hole in the brightest galaxy of the Abell 2597 cluster — the full galactic cycle of inflow and outflow powering this vast cosmic fountain has never before been observed in one system.
Lack of varied seasons and temperatures in tropical mountains have led to species that are highly adapted to their narrow niches, creating the right conditions for new species to arise in these areas, according to a new study published in the Proceedings of the National Academy of Sciences. Still, the same traits that make tropical mountains among the most biodiverse ecosystems on Earth also make
High blood pressure or hypertension is a major health problem that affects more than 100 million people in the US (using the current 130 systolic or 80 diastolic) and over one billion worldwide. Despite being considered a disease of older adults two new studies in the Journal of the American Medical Association (JAMA) are reporting the association of high blood pressure with the risk of premature
Researchers led by Tufts University biologists and engineers have found that delivering progesterone to an amputation injury site can induce the regeneration of limbs in otherwise non-regenerative adult frogs — a discovery that furthers understanding of regeneration and could help advance treatment of amputation injuries.
Scientists have identified an RNA molecule with broad powers to regulate the body's inflammatory response to infection and injury. Called lincRNA-Cox2, it belongs to a recently discovered, highly abundant class of RNAs whose functions are only beginning to be understood.
Pictures may be worth a thousand words, but icons may be even more powerful in nudging people to disclose more information online, according to an interdisciplinary team of Penn State researchers.
People younger than age 40 who have high blood pressure are at increased risk of heart failure, strokes and blood vessel blockages as they age, according to a study in JAMA led by Duke Health.
Sixty-nine pharmaceutical compounds have been detected in stream insects, some at concentrations that may threaten animals that feed on them, such as trout and platypus.
A team of scientists designed a device that can induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by 'kick-starting' tissue repair at the amputation site. Their findings, appearing Nov. 6 in the journal Cell Reports, introduce a new model for testing 'electroceuticals,' or cell-stimulating therapies.
Mitochondrial DNA depletion syndrome (MTDPS) is a group of genetic disorders that cause a significant reduction in mitochondrial DNA and ATP production. These syndromes are typically fatal during infancy. Currently, there are no treatment options; however, researchers at the Medical University of South Carolina have identified several drug candidates, including nicotinamide adenine dinucleotide (N
Dozens of common pharmaceuticals have been detected in Australian aquatic wildlife, suggesting an urgent need for improved wastewater purification processes
Scientists from ITMO University and Lebedev Physical Institute of the Russian Academy of Sciences have proposed a new microwave antenna that creates a uniform magnetic field in large volume. It is capable of uniform, coherent addressing of the electronic spins of an ensemble of nanodiamond structure defects. This can be used to create super-sensitive magnetic field detectors for magnetoencephalogr
A billion light-years from Earth lies one of the universe's most massive structures, a giant elliptical galaxy surrounded by a sprawling cluster of other galaxies known as Abell 2597. At the core of the central galaxy, a supermassive black hole is powering the cosmic equivalent of a monumental fountain, drawing in vast stores of cold molecular gas and spraying them back out again in an ongoing cyc
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Like many Americans, David Glosser has a lot of opinions about politics. When I spoke with him on the phone, he paused his diatribe against the Trump administration only to cough. But unlike most Americans, Glosser—a retired physician who lives in Yardley, Pennsylvania, which hugs the state’s border with New Jersey—is closely related to one of President Donald Trump’s most influential aides. His
The hacking attempts haven’t slowed. The disinformation campaigns are ongoing. And the warning lights have been “blinking red” for a potential foreign operation aimed at disrupting the U.S. 2018 midterm elections, according to the country’s top intelligence official. But if there is anything positive to take away from Russia’s election interference in 2016, it’s this: America’s election infrastru
In 2016, Donald Trump steamrolled to victory, and Facebook was a major reason why . Trump the candidate was immensely popular on the social network, and his team of digital campaigners spun up a complex voter-targeting scheme that seemed to work, aided by a powerful right-wing-media ecosystem , a gentle shove from Russian operatives , and maybe even Cambridge Analytica . It might have stood to re
An unspoken truth about the internet is that all social-media platforms eventually devolve into dating platforms , and Twitter is no different . This is the platform that invented the concept of sliding into someone’s DMs ; lurking and flirting are common among singles. But despite the fact that so many users are looking for love , actually acknowledging that you’ve found it—by tagging your signi
All over the world, countless conservation projects are taking place, attempting to achieve aims from reducing habitat loss, to restoring populations of threatened species. However there is growing awareness that conservationists have not always done a good enough job at evaluating whether the things they do really work.
A new study on mice shows that exercise helps them shiver longer. Brown fat did not seem to be the deciding factor in the mice's ability to combat the cold. The combination of exercise and brown fat is a more likely reason why we can endure extreme temperatures. None Scott Carney was skeptical when he first visited Wim Hof. Ice baths, hyperventilation, long breath holds, and scaling world-class m
It was the first Bose-Einstein condensate made in space Creating the condensate in low gravity allows it to hold longer Scientists hope Bose-Einstein condensate will allow finer detection of subtle quantum phenomena For six minutes, 150 miles above Kiruna, Sweden on January 23, 2017 floated the coldest known spot in the universe. As far as we know, the coldest anything in nature can be is absolut
Teachers felt immense pressure from school leaders and families to respond in a certain way—or not at all—in their classrooms following the 2016 presidential election, according to new research. The study, which appears in the American Educational Research Journal , addresses the widespread but often unspoken idea of political neutrality in the classroom, and how that’s not an effective teaching
Taiwan-based electronics manufacturer Foxconn is struggling to find enough skilled workers for its planned facility in Wisconsin and may bring in personnel from China, the Wall Street Journal reported Tuesday.
Irish budget airline Ryanair announced Tuesday it had shut down its Eindhoven base for winter, despite a Dutch court decision stopping it from forcing pilots there to transfer abroad.
When it comes to the search for extra-terrestrial life, scientists have a tendency to be a bit geocentric – i.e. they look for planets that resemble our own. This is understandable, seeing as how Earth is the only planet that we know of that supports life. As result, those searching for extra-terrestrial life have been looking for planets that are terrestrial (rocky) in nature, orbit within their
Sixty-nine pharmaceutical compounds have been detected in stream insects, some at concentrations that may threaten animals that feed on them, such as trout and platypus. When these insects emerge as flying adults, they can pass drugs to spiders, birds, bats, and other streamside foragers. These findings by an international team of researchers were published today in Nature Communications.
A team of scientists designed a device that can induce partial hindlimb regeneration in adult aquatic African clawed frogs (Xenopus laevis) by "kick-starting" tissue repair at the amputation site. Their findings, appearing November 6 in the journal Cell Reports, introduce a new model for testing "electroceuticals," or cell-stimulating therapies.
IIASA researchers have introduced a new, simple measure for human wellbeing across countries, called the Human Life Indicator (HLI), that takes inequality into account and could replace the commonly used but error-prone Human Development Index (HDI).
Scientists have discovered the inner workings of a known 'speed gene', which directly affects skeletal muscle growth and, in turn, race distance aptitude in thoroughbred racehorses. Their findings have important implications for a multi-billion dollar industry.
Researchers at Boston Medical Center found that frequent, persistent back pain is associated with earlier death in a study of more than 8,000 older women who were followed for an average of 14 years.
NASA's new 8-episode podcast series, On a Mission , is a ride-along for its InSight mission to Mars. InSight will look beneath the Martian surface for a deeper understanding of its composition and history. Each episode makes for a compelling half hour of listening. None It's called " InSight ," and it's NASA's latest spacecraft headed to Mars, scheduled to arrive there on November 29. As always,
The nucleus of a cell has something in common with a cardboard box full of kittens: People get so fascinated by the contents that they overlook the container. The nucleus itself is often treated as no more than a featureless membranous bag for holding the vitally dynamic genetic material. Yet in fact it has specialized parts and an internal architecture of its own, and scientists have long specul
Sign languages can help reveal hidden aspects of the logical structure of spoken language, but they also highlight its limitations because speech lacks the rich iconic resources that sign language uses on top of its sophisticated grammar.
Pollution in Russia increases along with economic growth, but only until it reaches a certain threshold, from where it starts to decrease, demonstrates a recent study conducted by Prof. Natalya Ketenci, Yeditepe University, Turkey.
To comply with nutrient-reduction goals in the Chesapeake Bay watershed, Pennsylvania may want to consider the establishment of animal agriculture operations in the western part of the state, according to a team of Penn State researchers.
Strap on a diving mask and fins and slip under the crystal-clear water near a coral reef in Indonesia, Papua-New Guinea or the Philippines, and you'll immediately see why divers and snorkelers from across the world flock to the area. Known as the Coral Triangle, the region is famous for its unmatched diversity of reef fish and other marine creatures.
Discoveries of biodiversity at the Lilliputian scale are more tedious than it is for larger animals like elephants, for example. Furthermore, an analysis producing a DNA barcode—a taxonomic method using a short snippet of an organism's DNA—is not enough to adequately identify it to the species level.
Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. Chemists at the Faculty of Chemistry of the University of Vienna and at McGill University have developed a new synthetic approach that allows RNA to be chemically synthesized about a million times more efficiently than previously possibl
A team of Penn Engineers has demonstrated a new material they call 'nanocardboard,' an ultrathin equivalent of corrugated paper cardboard. A square centimeter of nanocardboard weighs less than a thousandth of a gram and can spring back into shape after being bent in half. Nanocardboard's stiffness-to-weight ratio makes it ideal for aerospace and microrobotic applications, where every gram counts.
The University of Cincinnati is working with the Nevada Bureau of Mines and Geology to add specific details on landslides to the state's map of known hazards.
Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals. The report includes detailed clinical characterization of seven related Amish children who were homozygous for the variant. The children all exhibited poor growth, developmental delay, abnormal brain white matter, hearing los
Galaxy evolution can be chaotic and messy, but it seems that streams of cold gas spraying out from the region around supermassive black holes may act to calm the storm.
ALMA observations of Abell 2597 show the first clear and compelling evidence for the simultaneous infalling and outflow of gas driven by a supermassive black hole.
Each state takes a different approach on how it tries to stem the impact of opioid abuse, resulting in significant variation between opioid prescription rates and the number of children placed into foster care.
According to a new study that used data from the National Survey of Family Growth 2006-2015, lesbian women were less likely to report receiving a birth control prescription or birth control counseling compared with heterosexual women.
More than 20 million people board cruise ships each year to enjoy a little rest and relaxation. The lucky travelers liberally apply sunscreen before sunning themselves on deck, while the ship's intricate machinery chugs forward, propelling the vessel toward unknown destinations.
Are environmental changes in the Mediterranean region influencing human mobility in the West Asia and North Africa (WANA) region? That is the question that Bruno Venditto of the Institute of Studies on Mediterranean Societies, at the Italian National Council of Research, in Naples, Italy, sets out to answer in the International Journal of Migration and Residential Mobility.
In physical, biological and technological systems, the time that a system's components take to influence each other can affect the transition to synchronization, an important finding that improves understanding of how these systems function, according to a study led by Georgia State University.
Keith Allen Bledsoe, the sixth teenage homicide victim in Lexington, Kentucky, this year, died as the other five had: by gunshot . On June 26, Lexington police found the 17-year-old Bledsoe’s body in the streets of Harris Court, a cul-de-sac near I-64. If confrontation or argument had preceded Bledsoe’s murder, none of the neighbors reported hearing it to police. If they heard gunshots, seemingly
The 30-second ad shows Luis Bracamontes, an illegal immigrant who killed two policemen, and footage of the migrant caravan. Critics say the ad is racially charged and is meant to conjure fear before the midterm elections. Fox News, typically the most pro-Trump news channel, took some by surprise when it announced it would no longer air the commercial. Fox News will no longer air an immigration ad
Özlem Cekic's email inbox has been full of hate mail since 2007, when she won a seat in the Danish Parliament — becoming the first female Muslim to do so. At first she just deleted the emails, dismissing them as the work of fanatics, until one day a friend made an unexpected suggestion: to reach out to the hate mail writers and invite them to meet for coffee. Hundreds of "dialogue coffee" meeting
Researchers on the Broad Institute's Cancer Dependency Map (DepMap) team have released DEMETER2, an upgraded version of an open source software tool that identifies cancer cells' genetic dependencies (genes they need in order to survive).
In cooperation with French and Greek researchers, scientists from the National Research Nuclear University MEPhI have found a simple way to lower the production costs of nano-electronics through controlled deformation of nanotubes and other tiny objects. Their findings were published in Nanotechnology.
A pair of researchers with Queen's University in Canada has found that dominant species of birds in economically advanced cities have higher numbers than weaker species. In their paper published in Proceedings of the National Academy of Sciences, Paul Martin and Frances Bonier describe their study of hundreds of bird species living in cities around the globe and what they found.
A new study on mice shows that exercise helps them shiver longer. Brown fat did not seem to be the deciding factor in the mice's ability to combat the cold. The combination of exercise and brown fat is a more likely reason why we can endure extreme temperatures. None Scott Carney was skeptical when he first visited Wim Hof. Ice baths, hyperventilation, long breath holds, and scaling world-class m
Scientists at Helmholtz Zentrum München have discovered new details about the UHRF1 protein. UHRF1 catalyses particular steps that are required for marking DNA with epigenetic modifications that suppress parts of the genome. As reported in Molecular Cell, the molecule may serve as a target for drug therapies because it is produced at elevated levels in cancer cells.
A new condition, that occurs in the presence of both sarcopenia and obesity and termed as '[sarcopenic obesity', and that describes under the same phenotype the increase in body fat mass deposition, and the reduction in lean mass and muscle strength.
A new article by a Swansea University researcher has called for a rethink on tropical marine conservation efforts, as people who previously relied on coral reefs for food and income are increasingly looking to alternative habitats which is putting pressure on the animals that inhabit seagrass meadows.
An ECDC study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area (EU/EEA). The burden of disease is measured in number of cases, attributable deaths and disability-adjusted life years (DALYs). These estimates are based on data from the European Antimicrobial Resistance Surveillanc
Sign languages can help reveal hidden aspects of the logical structure of spoken language, but they also highlight its limitations because speech lacks the rich iconic resources that sign language uses on top of its sophisticated grammar.
Environmental pollution in Russia increases along with economic growth, but only until it reaches a certain threshold, from where it starts to decrease, demonstrates a recent study published in the open-access Russian Journal of Economics by Prof. Natalya Ketenci, Yeditepe University. Using data from 1991-2016, she also looks into the impact and causality of key determinants for CO2 emissions. As
Researchers at the Technical University of Munich (TUM), the Leibniz-Institute for Food Systems Biology, and the University of Hohenheim have developed a new methodical approach. It allows for the faster identification of flavor-giving protein fragments in foods such as cheese or yogurt, thus optimizing production processes.
The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them. Whether and how the intestinal flora will subsequently recover has been investigated by a research team that included scientists from the MDC. The results have been published in the scientific journal Nature Microbiology.
Although long life tends to run in families, genetics has far less influence on life span than previously thought, according to a new analysis of more than 400 million people. The results suggest that the heritability of life span is well below past estimates, which failed to account for our tendency to select partners with similar traits to our own. The research was published in GENETICS, a journ
K im Moore clapped, pulled out her smartphone, and zoomed in to snap a picture of President Donald Trump just a few hundred feet away on the stage Sunday night in Chattanooga. She and her husband listened as Trump talked about how one of the women who’d accused Brett Kavanaugh of sexual misconduct had recanted. They hadn’t heard of this before, quite possibly because it wasn’t true. The woman in
Vince Staples is always on the move, but his heart stays in the LBC. The North Long Beach–bred 25-year-old has spent much of his dizzying rap career joining the ranks of musicians who put on for their city before he was even born. Before Staples, there were Snoop Dogg, Warren G, and Daz Dillinger. There were Nate Dogg, Knoc-Turn’al, and RBX. Staples is a remarkable talent, and the booms and bounc
Alphabet's longevity lab Calico trawled through Ancestry's massive genealogy database to study human longevity—and found that DNA matters less than people have long believed.
For many people, a two-and-a-half-minute video of a baby brown bear trying to scale a snow-covered mountain was a life-affirming testament to the power of persistence. As it begins, the cub is standing with its mother on the side of a perilously steep ridge. The mother begins walking across, and despite slipping a few times on the loose snow, she soon reaches the top. Her cub, following tentative
A new article by a Swansea University researcher has called for a rethink on tropical marine conservation efforts, as people who previously relied on coral reefs for food and income are increasingly looking to alternative habitats which is putting pressure on the animals that inhabit seagrass meadows.
Dust particles in space form the basis for new stars and planets. But what do these particles consist of and how do they behave? Sascha Zeegers studied this. Ph.D. defence 1 November.
As biocatalysts, enzymes are involved in many metabolic processes. They bind to a particular substance, i.e. the substrate, and convert it. Generally, the substrate-binding pocket inside the enzyme determines which type of substrate it processes.
Researchers have developed a new nuclear medicine tracer that could improve diagnosis and treatment of non-small cell lung cancer. Research published in the November issue of The Journal of Nuclear Medicine found that the new tracer, 99mTc-HYNIC-cMBP, produced clearer images in less time than currently used tracers and was more rapidly eliminated from the body, reducing radiation exposure.
At the time when autism spectrum disorder (ASD) can be first reliably diagnosed, toddlers affected by ASD are already displaying emotional vulnerabilities potentially foreshadowing the emergence of co-morbid affective and behavioral conditions highly prevalent in older children, reports a study published in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP).
Researchers identify the function of a protein that controls allergic diseases. Study could lead to development of medications for autoimmune disorders and other diseases, such as certain types of cancer.
The closest place in the universe where extraterrestrial life might exist is Mars, and human beings are poised to attempt to colonize this planetary neighbor within the next decade. Before that happens, we need to recognize that a very real possibility exists that the first human steps on the Martian surface will lead to a collision between terrestrial life and biota native to Mars.
In its recently published action plan for batteries which identifies EU sources for the minerals required to produce batteries, the European Commission has highlighted the essential role mineral raw materials will play to transform Europe into a low-carbon and circular economy, while strengthening simultaneously Europe's production and value chains. The 36-months project INFACT, funded under the E
A new device can improve balance for Gulf War veterans with unexplained illnesses that cause fatigue, headaches, respiratory disorders, and memory problems. The study is the first to examine how Gulf War illnesses affect veterans’ vestibular systems, which are integral for balance, memory, and brain blood flow. The condition, which affects Gulf War veterans includes a cluster of medically unexpla
Iceland is a small country tucked away on the edge of Europe. It has a population of only about 340,000 people. Iceland's prisons are small too. There are only five, altogether housing fewer than 200 prisoners. Of these five, two are open prisons. I had visited them both before, and they left me intrigued. I wanted to get to know them better.
The good news about spanking is that parents today are less likely to do it to their children than parents in the past. The bad news is that parents today still spank their kids—a lot. “Some estimates are that by the time a child reaches the fifth grade [in the United States], 80 percent of children have been spanked,” says George Holden, a professor of psychology at Southern Methodist University
What would it take for Democrats to win the Senate? Until now, it’s a question most strategists have brushed off. Republicans may hold a one-seat majority in the Senate, but their members on the ballot on Tuesday include a litany of popular incumbents. Moreover, with 10 Democrats up for reelection in states Donald Trump carried in 2016, Republicans have concerned themselves not so much with maint
Bacteria have established various strategies to infect organisms and use them as sources of nutrients. Many microbes use toxins that break down membranes by simply piercing through the outer shell of the cells. Human-pathogenic bacteria such as the plague bacterium Yersinia pestis or other bacteria from the salmonella family developed a much more subtle mechanism: they inject their poison by apply
Time travel to the UK in 2025: Harry is a teenager with a smartphone and Pauline is a senior citizen with Alzheimer's who relies on smart glasses for independent living. Harry is frustrated his favourite online game is slow, and Pauline is anxious since her healthcare app is unresponsive.
A new study offers a potential explanation for why many patients with acute myeloid leukemia experience a relapse after a stem cell transplant, and suggests a therapeutic approach that may help them back into remission. Patients with AML, an aggressive cancer of the blood, often receive treatment in the form of stem cell transplantation, in which a compatible donor’s blood-forming cells are trans
Finnish-American research group has studied whether parents' gender preferences and investment in offspring are affected by their status, wealth, education or childhood environment. Instead, parental preferences were best predicted by their sex. These results help to make sense of the often contradictory findings on offspring sex preferences.
Risk factors of type 2 diabetes and cardiovascular disease accumulate in children who have poor aerobic fitness, a new study from the University of Eastern Finland shows. The study also found that the traditional way of expressing aerobic fitness in proportion to total body mass overestimates the role of aerobic fitness in identifying children at an increased risk of these diseases.
The international scientific team developed a new method for measuring the response of crystals on the electric field.The results a collaborative research done at the European Synchrotron Radiation Facility (ESRF) were published in the Journal of Applied Crystallography and appeared on the cover of the October issue.
IBS Scientists have explained how liquid-like droplets made of proteins and DNA form in vitro. Currently, there is a huge interest in understanding the molecular mechanisms behind the creation of such droplets, as it is linked to some human diseases, such as amyotrophic lateral sclerosis (ALS). The results showed how much the sequence of DNA matters in the formation of such droplets.
Researchers created the world's most powerful electromagnetic pulses to control a data-storage material's physical form, leading to a potential way to scale down memory devices and revolutionize how computers handle information.
Ten years of commercial airliner-based measurements uniquely revealed three-dimensional distribution of atmospheric CO2 and its seasonality over Asia Pacific. Asia has been only sparsely monitored for atmospheric CO2, despite the growing importance of the region in the global carbon cycle. The remarkable feature of CO2 over Asia is depleted CO2 concentrations confined in the Asian summer monsoon a
To evaluate in vivo physiological functions, electrophysiological signals must be monitored with high precision and high spatial or temporal resolution. Ultraflexible, multielectrode arrays (MEAs) were recently fabricated to establish conformal contact on the surfaces of organs and to measure electrophysiological signal propagation at high spatial-temporal resolution. However, plastic substrates w
Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the "RNA world" hypothesis, RNA is able to support life on its own because it can both store information and catalyze biochemical reactions. Even in modern life, the most complex molecular machines in all cells, the ribosomes, are mad
Over halvdelen af fyringerne i Region Sjælland rammer ikke medarbejdere i fronten men derimod i administrationen, siger regionsrådsformand Heino Knudsen.
An international team of astronomers has detected a new luminous quasar at a redshift of 7.02. The newly found quasi-stellar object (QSO), designated DELS J003836.10–152723.6, is the most luminous quasar known at a redshift of over 7.0. The discovery is reported in a paper published October 29 on the arXiv pre-print repository.
Performing the mental gymnastics of making the phoenetic distinction between words and phrases such as "I'm hear" to "I'm here" or "I can't so but tons" to "I can't sew buttons," is familiar to anyone who has encountered autocorrected text messages, punny social media posts and the like. Although at first glance it may seem that phonetic similarity can only be quantified for audible words, this pr
For Cainnon Gregg, 2018 started out as a great year. After leaving his job as an installation artist to become a full-time oyster farmer in Wakulla County, Florida in 2017, Gregg began raising small oysters in baskets or bags suspended in the shallow, productive coastal waters of Apalachicola Bay.
A trio of researchers from CSIC-Universitat de València and Universitat de Barcelona has used data from the IceCube detector in Antarctica to measure Earth's mass. In their paper published in the journal Nature Physics, Andrea Donini, Sergio Palomares-Ruiz and Jordi Salvado describe using data describing neutrinos passing through the Earth to learn more about the interior of the planet. Véronique
A team of scientists at DESY and Universität Hamburg has reached another milestone towards the direct imaging of individual biomolecules: the group led by Jochen Küpper from the Center for Free-Electron Laser Science developed a new experimental technique which enables the separation of different peptide structures in order to analyze and image them separately. The scientists report their method,
Gardeners might end up never planting the wrong bulb again after the Royal Horticultural Society (RHS) and Reading University successfully mapped a daffodil's chloroplast genome for the first time.
The world's tropical oceans are suffering turbulent times. Dire predictions of yet more disastrous coral bleaching episodes have been released, placing the very future of wonders like the Great Barrier Reef in danger. Without global action to prevent runaway climate change, we as individuals are largely powerless to stop such loss.
Astronomers have found some of the most distant galaxies in the universe, opening a window on a previously unknown period of cosmic history — Read more on ScientificAmerican.com
A new study published in the Journal of Pediatric Psychology highlights the need for psychological screening for families/primary caregivers after a child sustains a burn injury.
A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from China and the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells. The findings were recently published in a top-clas
Elke van Nieuwenhuijzen will be receiving her doctorate next Wednesday, 7 November, at Eindhoven University of Technology for her study of black fungus on oiled wood that behaves like a 'biofinish.' This layer colors the wood and actually protects it from wood rot and degradation by sunlight. An additional advantage: the fungus automatically repairs damage in the protective layer.
How did sound propagate inside the Mosque of Cordoba in the time of Abd al-Rahman I? Today, thanks to virtual simulation tools, it is possible to know the sound fields of spaces that no longer exist. This field of work is known as acoustic archaeology by some researchers. Working in this field, researchers from the Higher Technical School of Architecture at the University of Seville have carried o
Erik Trinkaus, an anthropologist at Washington University, has found what he describes as "an abundance of developmental anomalies" in people that lived during the Pleistocene. In his paper published in Proceedings of the National Academy of Sciences, he describes his study of fossils recovered from several sites in the Middle East and Eurasia, and what he found.
In American criminology, crime and other forms of deviance have often been attributed to individuals' definitions or internalized attitudes toward deviance. In previous studies, however, empirical tests of the causal processes of learning attitudes toward deviance have been relatively rare. Moreover, studies examining the mediating effect of a person's attitudes on the relationship of both peer re
Hitting a material with laser light sends vibrations rippling through its latticework of atoms, and at the same time can nudge the lattice into a new configuration with potentially useful properties – turning an insulator into a metal, for instance.
Soon you may no longer have to worry about how long your dental repairs will last. A new dental reconstruction material developed in Sweden offers unprecedented improvements over existing acrylate-based fillers.
At a 1978 launch party for Queen’s album Jazz , Freddie Mercury furnished a New Orleans hotel with nude waiters, snake charmers, and—according to rumor—trays of cocaine. For Mercury’s birthday in 1987, the singer drew 700 friends to Ibiza for a soiree that’s still commemorated annually on the island. At another birthday, in 1985 at a bar in Munich, he asked his guests to dress in black-and-white
Health Dsuvia should be available early next year. A new, super-powerful opioid drug just received a stamp of approval from the Federal Drug Administration (FDA).
There was a huge amount of excitement when the Higgs boson was first spotted back in 2012 – a discovery that bagged the Nobel Prize for Physics in 2013. The particle completed the so-called standard model, our current best theory of understanding nature at the level of particles.
A new computer model that uses machine learning and de-identified and aggregated search and location data from logged-in Google users was significantly more accurate in identifying potentially unsafe restaurants when compared with existing methods of consumer complaints and routine inspections, according to new research.
Researchers have found that produce is a reservoir for transferable antibiotic resistance genes that often escape traditional molecular detection methods. These antibiotic resistance genes might escape cultivation-independent detection, but could still be transferred to human pathogens or commensals. The results highlight the importance of the rare microbiome of produce as a source of antibiotic r
A team from The Hong Kong Polytechnic University (PolyU) developed a novel nanostructure embedded into a semiconductor nanofibre that results in superb conductivity. The nanocomposite addresses a key inhibitor to conductivity, with the potential to improve a wide range of applications, from batteries and solar cells, to air purification devices.
Cities are experimenting with fees for scooter companies desperate to leave their electric mobiles on their sidewalks. And that money could help them keep up with the evolving world of mobility.
A study conducted by an international team of researchers led by Agustín Sánchez-Lavega, professor of Physics at the UPV/EHU, reveals the existence of a rich diversity in the atmospheric phenomena confined inside Jupiter's spot as a result of the intense hurricane winds blowing around its periphery at speeds of about 450 km/hour.
No doubt about it, NASA explores some of the most awe-inspiring locations in our solar system and beyond. Once seen, who can forget the majesty of astronaut Jim Irwin standing before the stark beauty of the Moon's Hadley Apennine mountain range, of the Hubble Space Telescope's gorgeous "Pillars of Creation" or Cassini's magnificent mosaic of Saturn?
An international research team used a computer model to reconstruct the history of glaciation in the Alps, visualising it in a two-minute computer animation. The simulation aims to enable a better understanding of the mechanisms of glaciation.
The Gravity Recovery and Climate Experiment Follow-On (GRACE-FO) mission has resumed collecting science-quality data and planned in-orbit checks after successfully completing a switchover to a backup system in the microwave instrument (MWI) on one of the mission's twin spacecraft. The in-orbit checks include calibrations and other system tests, and are expected to continue until January, when GRAC
The latest advances in computing and virtual reality (VR) have enabled researchers at KAUST to develop a suite of apps that allow users to visualize and interpret large and complex datasets in three dimensions.
Elevated levels of trimethylamine N-oxide (TMAO) — a compound linked with the consumption of fish, seafood and a primarily vegetarian diet — may reduce hypertension-related heart disease symptoms. New research in rats finds that low-dose treatment with TMAO reduced heart thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension.
While continuous positive airway pressure (CPAP) continues to be the gold standard for treatment of sleep apnea, the cumbersome machines are often not well tolerated by patients. Because of this, less obtrusive oral appliances that thrust the jaw forward during sleep are becoming more popular. Mandibular protrusion enlarges the pharynx and stabilizes the upper airway. A new study demonstrates that
Drones are becoming ubiquitous—they help bridge inspectors examine otherwise inaccessible spaces, monitor crop health for farmers, and assist search and rescue teams. They are also a boon to bad guys, from drug runners to terrorists. That's where David Kovar, F17, comes in. He's formed a company to glean data from drones, to understand how they and other autonomous systems work—and who is operatin
Usually, researchers study the effect communications have on the target of a message, says Alcides Velasquez, University of Kansas assistant professor of communication studies. But in the case of a new study on social media and Latino political participation, Velasquez and his co-author looked at the effect on the ones pushing out the message.
As the Northern hemisphere starts to feel the cold winter approaching, research stations in Antarctica are emerging from their long dark winter and awaiting the arrival of fresh supplies after living months in isolation.
UCLA researchers invented a portable device that uses holograms and machine learning to identify and measure airborne biological particles, or bioaerosols, that originate from living organisms such as plants or fungi. Trained to recognize five common allergens—pollen from Bermuda grass, oak, ragweed and spores from two types of mold—the system classified samples with an accuracy of 94 percent usin
When considering whether to buy stock in a company, investors often look to the trading activity of the company's top executives. If the CEO or CFO has recently made large purchases of company stock, investors tend to assume the stock price is about to go up; if they are selling stock, on the other hand, the meaning is less clear.
Women in Africa with little formal education are delaying marriage—much like their better-educated peers, a new University of Michigan study indicates.
Voters will have their voices heard during Tuesday's midterm elections. Walter Mebane, professor of political science and statistics at the University of Michigan, is an expert on election forensics, a field devoted to using statistical methods to determine whether the results of an election accurately reflect the intentions of the electors.
Near the end of World War II, Germany launched thousands of what it called "retaliation weapons" or flying bombs at London. Here's a look at the buzz bombs and the destruction they wrought.
The state of youth sports in America is either booming or suffering, depending on which box score you’re checking. You could follow the money. Kids’ sports is a nearly $17 billion industry, which makes it larger than the business of professional baseball and approximately the same size as the National Football League. Or you could follow the kids. The share of children ages 6 to 12 who play a tea
Climate change is a linguistic challenge, as well as a technical one. Rather than fearmongering, talking about saving the environment like it is a series of achievable goals is something that people tend to respond to better. What's the biggest contributor to climate change? If you guess car exhaust, you're wrong. It's cooling chemicals, like the ones found in air conditioners and refrigerators.
Ninety-four district election officers. Thirteen hundred electoral jurisdictions. Multiple law enforcement agencies. The fight to keep the midterms safe has an unimaginable scope.
Diverse communities of plants and animals typically perform better than monocultures. However, the mechanisms that are responsible for this have so far been a mystery to science. Biologists at the University of Zurich have now been able to identify the genetic cause of these effects. Their findings might help to improve crop yield.
A new test for industrial catalysts developed by chemists at Utrecht University uses fluorescent molecules to show which of three catalysts works better than the others. This makes it much easier to work on improving the catalysts, while also making production processes in the chemical industry more sustainable. The researchers, under the leadership of Prof. Bert Weckhuysen, will publish their res
A collective-risk dilemma experiment with members of the public in Barcelona shows that people are more or less likely to contribute money to fight climate change depending on their wealth. And the results indicate that participants with fewer resources were prepared to contribute significantly more to the public good than wealthier people, sometimes up to twice as much.
Scientists at the RIKEN Center for Sustainable Resource Science in Japan have found that the protein NGA1 is critical for plants to have normal responses to dehydration. Published in Proceedings of the National Academy of Sciences, the study shows how NGA1 controls transcription of a key gene that ultimately allows plants to survive after periods of drought.
Quantum systems can be manipulated with extremely high precision, but not perfectly. Researchers in the Department of Physics at ETH Zurich have now demonstrated how to monitor and correct errors that occur during such operations.
Researchers from the Julius Kühn Institut, Germany have found that produce is a reservoir for transferable antibiotic resistance genes that often escape traditional molecular detection methods. These antibiotic resistance genes might escape cultivation-independent detection, but could still be transferred to human pathogens or commensals. The results, which highlight the importance of the rare mic
Regardless of how the midterm elections turn out Tuesday night, President Donald Trump will have at least one thing to celebrate: His mission to remake the Republican Party in his own image has been an unequivocal success. The MAGA- fication of the GOP that Trump first set in motion three years ago has continued apace this campaign season—with disloyal Republicans getting primaried and purged, fo
“There are more of us,” said Democratic Congressman Mark Pocan of Wisconsin. “We are America, and they are not.” Tuesday’s midterm elections will show whether he’s right. For two years, Democrats have been chasing explanations for how Donald Trump won—the Russians, that last-minute letter from Jim Comey, Hillary Clinton’s inept campaign, economic pain and backlash across the country that was deep
Researchers from the Julius Kühn Institut, Germany have found that produce is a reservoir for transferable antibiotic resistance genes that often escape traditional molecular detection methods. These antibiotic resistance genes might escape cultivation-independent detection, but could still be transferred to human pathogens or commensals.
Over de næste tre år skal en række amerikanske virksomheder og forskningsinstitutioner udvikle en ny type oplader til elbiler. Den skal kunne levere 400 kW direkte fra højspændingsnettet med bedre virkningsgrad end i dag. Både E.ON og Clever ser positivt på den nye teknologi.
Sundhedsministeriet har offentliggjort listen over de lægemidler, man tiltænker at lade farmaceuter på danske apoteker genordinere til patienter, som led i et lovforslag fra sundhedsminister, Ellen Trane Nørby (V).
A new computer model that uses machine learning and de-identified and aggregated search and location data from logged-in Google users was significantly more accurate in identifying potentially unsafe restaurants when compared with existing methods of consumer complaints and routine inspections, according to new research led by Google and Harvard T.H. Chan School of Public Health.
While continuous positive airway pressure (CPAP) continues to be the gold standard for treatment of sleep apnea, the cumbersome machines are often not well tolerated by patients. Because of this, less obtrusive oral appliances that thrust the jaw forward during sleep are becoming more popular. Mandibular protrusion enlarges the pharynx and stabilizes the upper airway. A new study in CHEST® demonst
A group gathers on a Nashville street corner, some rolling in wheelchairs and others walking. They have arrived holding their smartphones and make friendly chatter while a coordinator helps them log in to an app. Dispersing in small groups, they examine restaurants, cafes, and shops, looking for features signaling that disability is welcome there: a parking sign with the International Symbol of A
In exposing audiences to people who didn’t look, sound or behave like them, the show had a positive effect on society In the film adaptation of The Lord of the Rings , Bilbo asks Frodo: “Any chance of seeing that old ring of mine again? I should like to have held it one last time.” Like the ring, Big Brother – which had its final episode last night – was a drug. Who wouldn’t want more? But the ad
Biologists are keen to understand how a type of flatworm known as a planarian uses powerful stem cells to regenerate an entire body from a headless sliver of itself. (Image credit: Deep Look/Youtube)
Kriminalforsorgen har alvorligt brug for et nye klientsystem, som lige nu er i udbud. Det gamle system kan ikke implementere lovændringer hurtigt nok, og de ansatte må ty til manuelle løsninger.
Forbrugerne er stadigt mere bekymrede for håndteringen af persondata i virksomhederne. Nu vægter vi privacy højere end nemme løsninger. Forbrugermistillid er så magtfuld, at det kan koste en virksomhed livet, påpeger Gartner.
A man has died after being mauled by a shark in the third such attack in two months at a popular tourist site on Australia's Great Barrier Reef, authorities said Tuesday.
Online leader Amazon Inc. refused comment Tuesday on reports that it plans to split its new headquarters between two locations, possibly in New York City and Arlington, Virginia.
Toyota Motor Corp. reported a 28 percent surge in the last quarter on growing sales in Europe, Asia and the Americas and cost cutting. It raised its profit forecast for the full year.
A piranha's bite is definitely worse than its bark, but the bark has uses too. A new study of the sounds made by piranhas in the Amazon finds that their underwater "barks" are an effective tool for identifying different species in murky waters.
Elevated levels of trimethylamine N-oxide (TMAO) — a compound linked with the consumption of fish, seafood and a primarily vegetarian diet — may reduce hypertension-related heart disease symptoms. New research in rats finds that low-dose treatment with TMAO reduced heart thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension.
Rambøll advarede allerede i 2016 om adskillige usikkerheder i stationsombygningen, der endte med at blive voldsomt fordyret. Men konsulenterne blev bedt om at gennemgå alt andet end lige præcis det hjørne af budgettet, hvor de største problemer gemte sig.
Psychologists are faced with many patient mysteries. The cases reveal the complexity of humans. Neurologist Oliver Sacks wrote about a number of very strange cases. None As billions of people fade in and out of history on this dusty rock, there are bound to be many strange ones. With the advent of psychology, the study of those who don't fit the norm have provided many invaluable clues about who
A company called Epik, whose CEO defended Gab, offered domain-hosting services, while Cloudflare continues to protect Gab from denial-of-service attacks.
Some conversations are forgotten as soon as they are over, while other exchanges may leave lasting imprints. Researchers want to understand why and how listeners remember some spoken utterances more clearly than others. They're specifically looking at ways in which clarity of speaking style can affect memory.
Women who are 'larks', functioning better at the beginning of the day than the end of the day, have a lower of risk breast cancer, according to new research.
With thousands of fans, college basketball games can be almost deafening. Some arenas have decibel meters, which can provide some indication of the noise generated. Researchers wanted to see whether machine learning algorithms could pick out patterns within the raw acoustical data that indicated the crowd's mood, thereby providing clues as to what was happening in the game itself.
Advances in understanding adolescent brain development may aid future treatments of mental illness and alcohol and substance use disorders, according to new research.
New studies reveal that small, membrane-bound particles transported between cells have wide-ranging and long-term effects in the brain and throughout the body, from helping neurons communicate to passing the effects of stress onto the next generation. Such extracellular vesicles released from the brain into the blood can also provide a window into brain pathology to help with disease diagnosis.
What We’re Following To the Left?: Democrats think they can pick up governor’s seats in these states this midterm election. Meanwhile in New England, popular Republican governors of solidly blue states seem to be holding on to their leads. In Texas, strategies like strict voter-ID laws and redistricting have kept the GOP in power, Adam Serwer argues, detailing his own laborious process of registe
The largest genomic study of parasitic worms to date identified hundreds of thousands of new genes and predicted many new potential drug targets and drugs. Research will help scientists understand how these parasites invade, evade the immune system and cause disease.
New research suggests that it is important to identify people at risk for falls related to obesity and muscle weakness so that healthcare providers can offer appropriate solutions.
Scientists are pursuing a cross-collaborative effort that could potentially change the way cellular immunotherapies such as stem cell transplantation and CAR T-cell therapies are performed.
New research reveals that Aspergillus flavus, a fungus that produces carcinogenic aflatoxins that can contaminate seeds and nuts, has a multilegged partner in crime: the navel orangeworm caterpillar, which targets some of the same nut and fruit orchards afflicted by the fungus. Scientists report that the two pests work in concert to overcome plant defenses and resist pesticides.
People who have suffered traumatic brain injury had slower reaction times and more false starts after disrupted sleep than well-rested controls, according to a study presented at the Society for Neuroscience meeting.
Two decades ago, a landmark study highlighted the prevalence of medical errors and called for a national commitment to reduce patient harm. Despite substantial investment by government and private institutions to increase patient safety, progress has been slow and uneven. A new study sheds light on what more can be done.
Web browsers use GPUs to render graphics on desktops, laptops, and smart phones. GPUs are also used to accelerate applications on the cloud and data centers. GPUs are usually programmed using application programming interfaces, or APIs, such as OpenGL. OpenGL is accessible by any application on a desktop with user-level privileges. Since desktop or laptop machines by default come with the graphics
Most of those undergoing procedure in England did not appear to need it, report shows More than 88% of surgeries to remove children’s tonsils are unnecessary, according to new research, with experts warning the procedure could do more harm than good. According to researchers, about 37,000 tonsillectomies were performed on children in England by the NHS between April 2016 and March 2017, carrying
With thousands of fans clapping, chanting, shouting and jeering, college basketball games can be almost deafeningly loud. Some arenas have decibel meters, which, accurately or not, provide some indication of the noise volume generated by the spectators and the sound systems. However, crowd noise is rarely the focus of scientific inquiry.
Health Virtual reality might help solve the problem. Picture it: you’re in the street and the person standing beside you collapses. What do you do? If you step in, you’re more likely to end up performing CPR on a man than…
While microbial communities are the engines driving the breakdown of dead plants and animals, little is known about whether they are equipped to handle big changes in climate. In a new study, researchers examine what happens after microbial communities move into new climate conditions. The study is a first step toward understanding the vulnerability of these ecosystems to climate change.
A genetic scan of a massive number of samples taken from tuberculosis patients across China has shown a surprising genetic uniformity: just two 'strains' of the tuberculosis bacterium account for 99.4 percent of all cases.
Alcohol industry social responsibility schemes strengthen their own commercial interests while failing to reduce harmful alcohol use, according to a new worldwide study. Far from confirming industry claims that they can 'do good' with corporate campaigns, the findings suggest that the public health benefits are likely to be minimal. In fact, 11 percent of the industry actions had the potential for
A new gene therapy can turn certain brain glial cells into functioning neurons, which in turn could help repair the brain after a stroke or during neurological disorders like Alzheimer's or Parkinson's diseases.
Scientists have made a surprising discovery in their mission to understand how cells stay healthy, uncovering an important connection between a cell's sugar metabolism and its antioxidant response.
Scientists have discovered a previously unknown molecular vulnerability in two rare, aggressive, and hard-to-treat types of cancer, and say it may be possible to attack this weakness with targeted drugs.
Decisions about whether to build, remove or modify dams involve complex trade-offs that are often accompanied by social and political conflict. A group of researchers from the natural and social sciences, engineering, arts and humanities has joined forces to show how, where and when it may be possible to achieve a more efficient balance among these trade-offs.
Many farms have areas where the ground either floods or does not retain enough water or fertilizer for crops to thrive. Such marginal lands could become useful and potentially profitable if they are planted with perennial bioenergy crops such as shrub willow and switchgrass, researchers report.
Increased production of corn in the United States has largely been credited to advances in farming technology but new research shows that changing temperatures play a significant role in crop yield.
A new study showed that regardless of diet, a protein called Pannexin 1 significantly regulates the accumulation of fat in mice. The study suggests that a deletion of the Panx1 gene in the early stages of development of mouse fat cells increases the amount of fat accumulated, leading to a higher risk for obesity later in life.
One of Australia's biggest health issues could be checked if more people took up yoga or tai chi and reduced their blood pressure, an Australian study has found.
Studies that link breakdowns in the brain's blood vessels to Alzheimer's disease and vascular dementia were presented today at Neuroscience 2018, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health. Molecules that signal damage in these systems could aid in earlier detection of these diseases and inform more effective in
Scientists have found that the protein NGA1 is critical for plants to have normal responses to dehydration. The study shows how NGA1 controls transcription of a key gene that ultimately allows plants to survive after periods of drought.
A new study quantifies for the first time how quickly rapid advancements in genomics may benefit patients. The research includes a five-year review of more than 300 epilepsy cases that showed about a third of children had a change in diagnosis based on new data. In some cases, the review helped doctors prescribe a more effective treatment.
New research has uncovered genetic variations that may contribute to the development of non-alcoholic fatty liver disease (NAFLD), the leading cause of liver disease.
How does our nervous system motivate us to get off the sofa and walk to the fridge, or even to the supermarket, to get food? A research team investigated this using the threadworm Caenorhabditis elegans. The results indicate how foraging behavior in higher animals might have evolved.
With this year’s Society for Neuroscience (SfN) annual meeting now in full swing, downtown San Diego couldn’t be more bustling. Everywhere you turn, street signs, store windows, and flyers read “Neuroscience 2018” to encourage visitors to check out at least one of the many events happening at the San Diego Convention Center. Helping to kick off the meeting on Saturday was the Brain Awareness Camp
Written by Elaine Godfrey ( @elainejgodfrey ) Today in 5 Lines The U.S. renewed the sanctions against Iran that were lifted under the 2015 nuclear deal, but issued “temporary” waivers to eight countries, allowing those nations to continue buying oil from Iran without penalty. NBC and Fox News said they will no longer air an immigration ad from President Donald Trump that has been widely criticize
Gadgets Google Home Minis and Echo Dots are really cheap this holiday, but they're complicated gifts. A smart speaker is fun to unwrap, but things get complicated once its set up.
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Bladet bringer aktuelle, spændende forskningsnyheder inden for biologi, medicin og andre naturvidenskabelige områder som f.eks. klimaændringer, nanoteknologi, partikelfysik, astronomi, seksualitet, biologiske våben, ecstasy, evolutionsbiologi, kloning, fedme, søvnforskning, muligheden for liv på mars, influenzaepidemier, livets opståen osv.
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