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Udenrigsministeriet har defineret korruption som »misbrug af betroet magt for egen vindings skyld«. Uundgåeligt er det begrebet, der trænger sig på, når man læser Ingeniørens nylige afsløring af, hvordan Trafikstyrelsen, udviklingsselskabet By & Havn og det ellers meget anerkendte private konsulentfirma DHI har håndteret en undersøgelse, der uvildigt skulle undersøge propeffekten af Lynetteholm. I
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Estoniafilmarna överklagar till HD Utdrag: “Den femdelade dokumentären ‘Estonia – fyndet som ändrar allt’ vann 2020 Stora Journalistpriset i kategorin ‘Årets avslöjande’. Dokumentären har samtidigt varit hårt kritiserad. Kritiker som … Continued Inlägget dök först upp på Vetenskap och Folkbildning .
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Fåglar och groddjur trivs tillsammans, men fåglar och fiskar har en mer komplicerad relation. För att ta hänsyn till alla arter kan separata våtmarker vara lösningen, menar forskare. Inlägget dök först upp på forskning.se .
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When Ravi Yekkanti puts on his headset to go to work, he never knows what the day spent in virtual reality will bring. Who might he meet? Will a child’s voice accost him with a racist remark? Will a cartoon try to grab his genitals? He adjusts the extraterrestrial-looking goggles haloing his head as he sits at the desk in his office in Hyderabad, India, and prepares to immerse himself in an “offi
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This article is from The Checkup, MIT Technology Review’s weekly biotech newsletter. To receive it in your inbox every Thursday, sign up here . Feces are good for so much more than flushing. Yes, our waste contains the stuff that our bodies are generally trying to get rid of. But it can also provide insight into our gut microbiomes and how they influence our health. And we’re getting closer to un
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A lot of the focus on genAI's implications on the job market seem to focus on how it'll eliminate or devalue certain professions. But what kind of new roles could generative AI augment or create ? You know, aside from prompt engineers who are astoundingly good at getting Midjourney to depict a human being with five, non-webbed fingers. submitted by /u/BorgesBorgesBorges60 [link] [comments]
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Nature Communications, Published online: 28 April 2023; doi:10.1038/s41467-023-37889-9 The authors unveil the many-particle processes underpinning the formation of bound charge transfer excitons at the interface of hBN-encapsulated lateral MoSe2-WSe2 heterostructures. The excitons can be tuned via interface (i.e. high quality lateral junction) and dielectric (i.e. hBN encapsulation) engineering.
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Nature Communications, Published online: 28 April 2023; doi:10.1038/s41467-023-38191-4 The authors present a method for super-resolution quantum microscopy at the Heisenberg limit by using pairs of entangled photons with balanced pathlengths. They improve the spatial resolution, imaging speed, and contrast-to-noise ratio in practice while providing a theoretical interpretation of the super-resolu
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Nature Communications, Published online: 28 April 2023; doi:10.1038/s41467-023-38164-7 Artificial molecular machines have captured the imagination of researchers, given their clear potential to mimic and influence human life. Here, the authors use a DNA cube framework for the design of a dice device at the nanoscale to reproduce probabilistic events in different situations such as equal probabili
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People leave jobs all the time, whether they're laid off, fired, or just quit. But how do their departures affect coworkers left behind? According to a new study from the UBC Sauder School of Business, those exits can lead many others to call it quits.
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A sea anemone found off Japan does not just live on a species of crab, but actually grows its host’s shell like a home extension Deep in the Kumano Sea off the south-eastern coast of Japan, hermit crabs crawl around sporting what look like pearly pink flowers on their shells. But these are not floral arrangements – they are members of a newly discovered species of sea anemone, Stylobates calcifer
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In “Good Girls,” Hadley Freeman draws on her own experience with the disorder as well as interviews with experts and former patients to shed light on a disease that has long resisted explanation and treatment. “No one actually has any definite answers about who develops anorexia and why,” Freeman writes.
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An observation of Anzac Day in Australia, classic car racing in England, an ongoing drought in Spain, an ultramarathon held in the Moroccan desert, rising floodwaters in California, a robotic humanoid companion in Italy, a cycling race through Belgium, superbloom flowers in California, and much more
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Schneider Shorts 28.04.2023 – old American papers in need of fixing, young russian and Iranian researchers in need of helping, French whistleblowers in need of punishing, Austrian anti-aging supplements in need of advertising, with an anti-aging pimp on cocaine, depressive fish in China, cured Israeli soldiers, and finally, retractions in full, in part and not at all.
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I feel like a decade ago that was really promising for all kinds of medical problems. We thought we could regrow limbs, cure blindness and deafness, get rid of all kinds of scarring etc. Is stem cell research a bust (to use a term from sports)? submitted by /u/fangfried [link] [comments]
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Even as a little kid (I’m a 2005 born) I noticed 50s nostalgia (my parents are 1970s born so I saw back to the future a lot and remember the 50s nostalgia in the original. I also remember hearing about happy days and just kind of having a romanticized view of the 50s even though I’m a racial minority.) And, of course, as someone who basically grew up in the 2010s (feels so weird to say) I remembe
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Att läsa skönlitteratur är ett sätt för blivande läkare att samla på sig människoöden. Att diskutera dem med sina kursare leder ofta till aha-upplevelser. Vi intervjuar litteraturvetaren Katarina Bernhardsson från Lunds universitet om medicinsk humaniora som numera ingår i läkarutbildningen.
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Nature Communications, Published online: 28 April 2023; doi:10.1038/s41467-023-38125-0 A challenge in diagnostics is integrating different data modalities to characterize physiological state. Here, the authors show, using the heart as a model system, that cross-modal autoencoders can integrate and translate modalities to improve diagnostics and identify associated genetic variants.
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Humans with condition can have disturbed sleep, and similar symptoms in dogs indicate cognitive decline is under way From loud snores to twitching paws, dogs often appear to have a penchant for a good snooze. But researchers have said elderly canines with dementia appear to spend less time slumbering than those with healthy brains – mirroring patterns seen in humans. It has long been known that p
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In people with Alzheimer's, the earliest symptoms are commonly disruptions in sleep rhythms. These include daytime sleepiness, showing agitation or confusion around dusk, staying awake longer, and waking up often at night. These changes are thought to result from damage to sleep-regulating areas in the brain. Alzheimer patients tend to spend less time in both REM (rapid eye movement) sleep, in whi
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. More than six months after the FDA announced a shortage of the ADHD drug Adderall and its generic variations, many Americans who rely on the medication continue struggling to obtain it. This supply cri
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Ett nytt värmerekord väcker oro i forskarvärlden. Aldrig sedan mätningarna började för drygt 40 år sedan har havsytans genomsnittstemperatur varit så hög som i april. – En riktig överraskning, och mycket oroande. Det kan vara ett kortvarigt extremvärde eller början på något mycket mer allvarligt, säger oceanografen Mike Meredith till The Guardian.
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The chants of his name defined a decade: “Jerry! Jerry! Jerry!” Jerry Springer died today at 79. His most obvious legacy will be the syndicated talk show that bore his name—one that embodied the frenetic voyeurism of the American ’90s. Sex, affairs, secret children, incest, love triangles, love trapezoids, more sex, people wrestling and sparring and throwing chairs at one another: The Jerry Sprin
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Crop yield can be maximized when the best genetic variety and most effective crop management practices are used for cultivation. Scientists have developed various machine learning models to predict the factors that produce the greatest yield in specific crop plants. However, traditional models cannot accommodate high levels of variation in parameters or large data inputs.
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Crop yield can be maximized when the best genetic variety and most effective crop management practices are used for cultivation. Scientists have developed various machine learning models to predict the factors that produce the greatest yield in specific crop plants. However, traditional models cannot accommodate high levels of variation in parameters or large data inputs.
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Recently, Science China Earth Sciences published a paper about the transformation of organic matter by microorganisms under anoxic/hypoxic conditions. With the intensification of water eutrophication and global warming, hypoxia occurs frequently in coastal waters. In this study, the researchers performed an experiment to investigate changes in microbial community and the molecular characteristics
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Membrane separation technology has been widely recognized as a more advantageous technology owing to its high treatment efficiency, low footprint, reliable effluent quality. However, its further sustainable growth has been hampered due to membrane fouling. Although great efforts have been made in the recent decades to improve the antifouling performance via various modification strategies, but the
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Paleontologists from Brazil and Chile reveal an important discovery about the past of the most inhospitable continent on Earth, Antarctica. Today covered in snow, in the past, however, the location was not like this. The research, led by Brazilian paleobotanist Dr. Joseline Manfroi, along with her collaborators, proves that Antarctica was disturbed by frequent forest fires that were directly assoc
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See Spot Speak As if robotic dogs weren't creepy enough. A team of programmers just equipped a Boston Dynamics robot dog with OpenAI's ChatGPT and Google's Text-to-Speech voice modulation, allowing it to literally speak to them and answer their questions. In a video posted to Twitter , machine learning engineer Santiago Valdarrama showcased how he and a colleague programmed a Spot robot dog to ve
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Paleontologists from Brazil and Chile reveal an important discovery about the past of the most inhospitable continent on Earth, Antarctica. Today covered in snow, in the past, however, the location was not like this. The research, led by Brazilian paleobotanist Dr. Joseline Manfroi, along with her collaborators, proves that Antarctica was disturbed by frequent forest fires that were directly assoc
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A few things happened when SpaceX’s uncrewed experimental rocket blasted off and then exploded mid-flight last week. The engineers who’d designed it let out a deep sigh, maybe a couple of groans. The Federal Aviation Administration, which regulates rocket launches, began a standard investigation into what happened. Elon Musk congratulated his staff on a good start. And in a small nearby city, ash
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Imagine walking through a field on a hot, dry summer day. There is nobody around and the world is blissfully quiet – at least, you think it is. If only you could hear sounds at ultrasonic frequency, you would in fact hear loud “screaming” coming from all around you. You would hear the surrounding plants […]
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Most crystalline materials are polycrystals, such as metals. They are composed of many small crystalline grains with different lattice orientations. The interface between two crystalline grains, i.e., the grain boundary, is a thin layer of disordered particles about one or two particles thick.
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Editor’s Note: Read Kenan Orhan’s new short story “ The Renovation .” “ The Renovation ” is a new story by Kenan Orhan . To mark the story’s publication, Orhan and Oliver Munday , the associate creative director of the magazine, discussed the story over email. Their conversation has been lightly edited for clarity. Oliver Munday: Your new story, “The Renovation,” opens with an absurdist premise:
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Editor’s Note: Read an interview with Kenan Orhan about his writing process. I didn’t know by what accident the builders had managed it, but instead of a remodeled bathroom attached to my bedroom, they had installed Silivri Prison. No mistaking it. After the laborers had packed up their tools and cleaned up their mess (they had almost superstitiously prevented me from checking on their progress),
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Most Gen Z young people are characterized as ambitious and forward-thinking, believing all things are possible. But what if you are a teen whose father is, or has been, in prison? How does that affect your outlook on life? How does that affect your optimism in regard to going to college and completing your degree?
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Director's Cut In a recent panel interview with Collider , Joe Russo, who has directed big Marvel movies like "Avengers: Endgame" alongside his brother, shared some of his thoughts on how AI might impact the film industry, giving it about two years before AI can create a fully-fledged movie. "We're in a world where the entire generation has a facile expertise in [AI], and is also not afraid of it
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Thanks to great technological advances, the genetic material of living beings can now be sequenced at a rapid rate. Comparisons of genomes, whether of closely related or completely different species, reveal particularly interesting findings. In this way, information can be obtained on phylogenetic relationships, the formation of characteristics or on adaptive abilities.
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The American beech, Fagus grandifolia, is a North American staple and the dominant species in many northeastern forests. In 2012, a new disease was first spotted, infecting trees in northeastern Ohio. The worst afflicted had dark banding on their leaves, which emerged crumpled and leathery in the spring. Not until 2018 would experts discover the nematode pest, Litylenchus crenatae mccannii, overwi
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Thanks to great technological advances, the genetic material of living beings can now be sequenced at a rapid rate. Comparisons of genomes, whether of closely related or completely different species, reveal particularly interesting findings. In this way, information can be obtained on phylogenetic relationships, the formation of characteristics or on adaptive abilities.
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The American beech, Fagus grandifolia, is a North American staple and the dominant species in many northeastern forests. In 2012, a new disease was first spotted, infecting trees in northeastern Ohio. The worst afflicted had dark banding on their leaves, which emerged crumpled and leathery in the spring. Not until 2018 would experts discover the nematode pest, Litylenchus crenatae mccannii, overwi
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A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A). This structure and other findings in the new study could be harnessed to engineer new BoNT/E variants with modified specificities toward di
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A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A). This structure and other findings in the new study could be harnessed to engineer new BoNT/E variants with modified specificities toward di
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Johnny He The former director of a cancer research center faked data and presented others’ published data and text as his own in four grant applications to the National Institutes of Health (NIH) and one research record, according to a U.S. government watchdog. Johnny J. He , a professor of microbiology and immunology at the Rosalind Franklin University of Medicine and Science (RFUMS) in Chicago,
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What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard.
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Hair styling can be a potent form of self-expression, whether it features dramatic updos, intricate braids or crazy colors. Beyond being a reflection of our personality, these strands contain compounds that could one day appear in bandages, sunscreens or other products. Researchers reporting in ACS Omega have now designed a simple, green process to extract both keratin and melanin from human hair
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Managing the benefits of nature-based solutions across climate, biodiversity and society is of critical importance for meeting targets for climate neutrality and biodiversity restoration targets. Recent studies call for research into the interplay between biodiversity, climate adaptation and mitigation as well as environmental justice outcomes.
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Throughout the world, we are witnessing not just a decline in the numbers of individual insects, but also a collapse of insect diversity. Major causes of this worrying trend are land-use intensification in the form of greater utilization for agriculture and building development as well as climate change and the spread of invasive animal species as a result of human trade.
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Hair styling can be a potent form of self-expression, whether it features dramatic updos, intricate braids or crazy colors. Beyond being a reflection of our personality, these strands contain compounds that could one day appear in bandages, sunscreens or other products. Researchers reporting in ACS Omega have now designed a simple, green process to extract both keratin and melanin from human hair
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Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs. In collaboration with scientists at other institutions, the group used their new approach to find small molecules that can alter the activity of proteins involved in cancer.
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Throughout the world, we are witnessing not just a decline in the numbers of individual insects, but also a collapse of insect diversity. Major causes of this worrying trend are land-use intensification in the form of greater utilization for agriculture and building development as well as climate change and the spread of invasive animal species as a result of human trade.
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This month, a local TV-news station in Arizona ran an unsettling report: A mother named Jennifer DeStefano says that she picked up the phone to the sound of her 15-year-old crying out for her, and was asked to pay a $1 million ransom for her daughter’s return. In reality, the teen had not been kidnapped, and was safe; DeStefano believes someone used AI to create a replica of her daughter’s voice
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I magine you’re in the heart of New York City—for example, on the steps of Madison Square Garden. One of the very first things you would notice there, no matter the time of day or the weather, would be the pungent aroma of burning reefer. This would also be the case if you found yourself at the entrance to the Q train at Union Square, or at a chessboard in Washington Square Park, or under some sc
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Extremely Quiet Luxury If you haven't seen Amazon founder Jeff Bezos' Coachella fit yet, maybe stop scrolling. Save yourself. It's scarring. Bezos and his girlfriend, alive girl Lauren Sánchez, took to the influencer-laden festival scene last weekend, flanked by their couple friends , momager Kris Jenner and her boyfriend, Corey Gamble. You'd think that with a current net worth of $114 billion ,
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When one thinks of the damage that climate change is doing, it's probable that what comes to mind is a vision of huge lumps of ice dropping off one of the polar ice sheets and crashing into the ocean. While Greenland and Antarctica are losing masses of ice, so too are most of the glaciers around the world, but it's tricky to measure how much ice they are shedding.
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PLANETARY SCIENCE Mars’s moon may be its kin Researchers have long believed that Mars’s two moons, Deimos and Phobos, are captured asteroids. But the first close-up images of Deimos, taken by the United Arab Emirates’s $200 million Hope spacecraft, suggest the 12-kilometer-wide body instead formed from the same material as Mars, researchers revealed this week at the annual meeting of the Europe…
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HomeScienceVol. 380, No. 6643ZoonomiaBack To Vol. 380, No. 6643 Full accessIntroduction to Special Issue Share on ZoonomiaSacha VignieriAuthors Info & AffiliationsScience27 Apr 2023Vol 380, Issue 6643pp. 356-357 NEXT ARTICLEGenomics expands the mammalverseNext ContentsInformation & AuthorsMetrics & CitationsView OptionsReferencesMediaTablesShareThe 240 mammals sequenced through the Zoonomia pro…
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Increasingly hot topics in both science and journalism are diversifying the practitioners of these professions and examining what is meant by “objectivity” in this improved world. Bringing wider experiences and perspectives to the laboratory or the …
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As the Arctic warms and loses sea ice, trans-Arctic shipping has increased, reducing travel time and costs for international trade. However, a new study finds that the Arctic Ocean is getting foggier as ice disappears, reducing visibility and causing costly delays as ships slow to avoid hitting dangerous sea ice.
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The written word is said to reflect one's emotions and attitude. By analyzing text, we can make educated guesses about an author's feelings. People who write in a good mood may use words that exude a pleasant fragrance, akin to a rose. Conversely, when they write while feeling upset or angry, their words may seem prickly, like thorns. Could an artificial intelligence (AI) program that accesses vas
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In the run-up to the 2020 election, people appear to have become better at spotting misinformation online, according to a study that found a decline in clicks on unreliable websites. According to prior research, some 44.3% of Americans visited websites during the 2016 US election that repeatedly made false or misleading information. During the 2020 election, that number dropped by nearly half to
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Over the past 100 million years, mammals have adapted to nearly every environment on Earth. Scientists with the Zoonomia Project have been cataloging the diversity in mammalian genomes by comparing DNA sequences from 240 species that exist today, from the aardvark and the African savanna elephant to the yellow-spotted rock hyrax and the zebu.
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More than a million years ago, large chunks of the human genome were rearranged—a chance event during egg or sperm formation that led to the deletion, duplication, or reversal of sections of DNA. Those structural variants, researchers have now discovered, likely set off a cascade of other rapid changes in human DNA that may underlie uniquely human features, particularly the brain.
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CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral DNA and RNA. A new study published in Science reveals a previously unrecognized player in one such system—a membrane protein that enhances anti-viral defense—simultaneously broad
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Human lifespan is related to the aging of our individual cells. Three years ago a group of University of California San Diego researchers deciphered essential mechanisms behind the aging process. After identifying two distinct directions that cells follow during aging, the researchers genetically manipulated these processes to extend the lifespan of cells.
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Solving a riddle that has confounded biologists since bacterial spores—inert, sleeping bacteria— were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.
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Over the past 100 million years, mammals have adapted to nearly every environment on Earth. Scientists with the Zoonomia Project have been cataloging the diversity in mammalian genomes by comparing DNA sequences from 240 species that exist today, from the aardvark and the African savanna elephant to the yellow-spotted rock hyrax and the zebu.
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Contrary to what is stated in biology textbooks, the growth of fish doesn't slow down when and because they start spawning. In fact, their growth accelerates after they reproduce, according to a new article published in Science.
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More than a million years ago, large chunks of the human genome were rearranged—a chance event during egg or sperm formation that led to the deletion, duplication, or reversal of sections of DNA. Those structural variants, researchers have now discovered, likely set off a cascade of other rapid changes in human DNA that may underlie uniquely human features, particularly the brain.
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CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral DNA and RNA. A new study published in Science reveals a previously unrecognized player in one such system—a membrane protein that enhances anti-viral defense—simultaneously broad
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Human lifespan is related to the aging of our individual cells. Three years ago a group of University of California San Diego researchers deciphered essential mechanisms behind the aging process. After identifying two distinct directions that cells follow during aging, the researchers genetically manipulated these processes to extend the lifespan of cells.
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The Picts of Scotland who have long intrigued and have been ascribed exotic origins in fact descended from indigenous Iron Age society and were genetically most similar to people living today in Scotland, Wales, North Ireland and Northumbria. Adeline Morez of Liverpool John Moores University and Linus Girdland-Flink of the University of Aberdeen report these findings in a new study published April
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I'm curious what the future of wildlife will be like, everyone is wondering, if AI will replace humans in the future, will humans merge with machines, will humans colonize space, but very rarely do I see anyone asking the question, what about nature? Has man, in pursuit of technological development, forgotten that not only his species lives on earth? What do you think, will human use future techn
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With the advent of AI, white collar jobs would decline. Only few professions such as doctor, lawyer, cops, and administrators would have significance. Though almost all countries would raise drone armies, no country would dare to leave everything to robots and drones. Agriculture, prostitution, and trading would continue as these industries suffice basic needs of humans. Only difference would be
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The title. Last I remember they were polling people on when the covid vaccine was going to be released and I think the crowd got it right. Did I lose track of where that platform went or did it cease to exist? Is there an explanation why? It's such an interesting concept. submitted by /u/FoxyRoxyMoxy [link] [comments]
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Moon Morale The UAE's hopes and dreams of a Moon landing lay in its glorious Rashid mini rover — so it's too bad it ended up unceremoniously smashing into the lunar surface . It's a disappointing outcome to what could've been a historic mission, but scientists at the Mohammed Bin Rashid Space Centre (MBRSC) in Dubai don't seem too beat up about it, choosing to look at the bright side of things. "
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Digital Dog-sters New York recently deployed a robot dog to the scene of a catastrophe to uncover a body— and according to the city's unpopular mayor , this dystopian factoid is good, actually. In a press conference , New York City Mayor Eric Adams hailed the FDNY's Boston Dynamics-developed and Dalmatian-painted "Digidog," which last week uncovered the one person who died in a Lower Manhattan ga
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Some modern Alaska Natives still live almost exactly where their ancestors did some 3,000 years ago, according to ancient genetic data analyses. The first people to live in the Americas migrated from Siberia across the Bering land bridge more than 20,000 years ago. Some made their way as far south as Tierra del Fuego, at the tip of South America. Others settled in areas much closer to their place
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38116-1 The dynein motor complex has a variety of important functions in both dividing and non-dividing cells. Here, Gallisà et al. describe a mode of regulation of dynein based on the phosphorylation of its adaptor BICD2 by the kinase PLK1, and how this is central for the regulation of centrosome position in G2 and M.
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Protists, a broad class of generally single-celled organisms that includes algae and amoebae, have long been regarded as a "catch-all" category for diverse microorganisms. Because of their diversity and prevalence, protists play vital roles in virtually every ecosystem on earth. But until recently, one of those roles was poorly understood.
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A team of engineers and materials scientists affiliated with multiple institutions in the U.S., has developed a new way to depolymerize plastics using electrified spatiotemporal heating. In their paper, published in the journal Nature, the group describes the new process and its efficiency. Nature has also published a Research Briefing in the same journal issue outlining the work done by the team.
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Soybean (Glycine max) is an important economic crop, providing 28.7% of the world's vegetable oil and 70.7% of its protein meal. Seed weight is usually associated with seed size and is one of the most important agronomic traits determining yield. However, understanding of the genetic and molecular basis of soybean seed size/weight control is very limited.
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Single-cell RNA-sequencing (scRNA-seq) technologies offer the opportunity to understand regulatory mechanisms at single-cell resolution. Gene regulatory networks (GRNs) provide a crucial blueprint of regulatory mechanisms in cellular systems and thus play a central role in biological research. It is therefore imperative to develop an accurate tool for inferring GRNs from scRNA-seq data.
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Human lives have been revolutionized since lithium-ion batteries (LIBs) were successfully commercialized. However, modern portable electronics have increased energy demands and thus require batteries with high energy density. Directly using Li metal as an anode is considered a promising strategy due to its ultra-high capacity (3860 mA h g-1) and low negative electrochemical potential (- 3.04 V ver
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More than ever before, humans seem to be inundated with stories. They pour out of our screens and social-media feeds, our books, and, of course, ourselves. The urge to create narratives in order to make sense of reality is matched only by the need to escape reality by the same means. Amid this abundance, fairy tales have found renewed popularity in recent years. Best-selling authors such as Maris
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Soybean (Glycine max) is an important economic crop, providing 28.7% of the world's vegetable oil and 70.7% of its protein meal. Seed weight is usually associated with seed size and is one of the most important agronomic traits determining yield. However, understanding of the genetic and molecular basis of soybean seed size/weight control is very limited.
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Single-cell RNA-sequencing (scRNA-seq) technologies offer the opportunity to understand regulatory mechanisms at single-cell resolution. Gene regulatory networks (GRNs) provide a crucial blueprint of regulatory mechanisms in cellular systems and thus play a central role in biological research. It is therefore imperative to develop an accurate tool for inferring GRNs from scRNA-seq data.
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Photoacoustic tomography (PAT) is a hybrid imaging technique that combines optical illumination with ultrasound detection for high-resolution imaging of deep tissues. Utilizing the photoacoustic (PA) effect, PAT provides a distinct advantage with scalable resolution, higher imaging depth, and high contrast imaging. It uses nanosecond laser pulses to illuminate the tissue of interest, enabling thei
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In a recent paper, "Boundary Vector Cells in the Goldfish Central Telencephalon Encode Spatial Information," published in PLOS One, researchers at Ben-Gurion University in Israel and the Institut de Biologie de l'École Normale Supérieure in France, studied the cognitive activity of goldfish navigating a fish tank.
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Models based on the principles of statistical physics can provide useful insights into how languages change through contact between speakers of different languages. In particular, the analysis reveals how unusual linguistic forms are more likely to be replaced by more regular ones over time.
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Energy efficient LEDs (light emitting diodes) have begun to replace many types of lighting both indoor and outdoor. A key reason for the rise of LEDs has been materials research that greatly improved the quality and intensity of light achievable with these devices. But those materials must be handled with very high levels of precision, including surfaces that are as defect-free as possible.
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When two black holes merge, they emit gravitational waves that race through space and time at the speed of light. When these reach Earth, large detectors in the United States (LIGO), Italy (Virgo) and Japan (KAGRA) can detect the signals. By comparing against theoretical predictions, scientists can then determine the black holes' properties: masses, spins, orientation, position in the sky and dist
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A team of researchers, led by University of Texas at Dallas scientists, has developed a new technique to grow exceptionally large, high-quality crystals that could help make advanced electronics, such as spintronic and magnetic optoelectronic devices, a reality.
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Three new Roman fortified camps have been identified across northern Arabia by a remote sensing survey by the University of Oxford's School of Archaeology. Their paper, published in the journal Antiquity, reports the discovery may be evidence of a probable undocumented military campaign across south east Jordan into Saudi Arabia.
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Coal trains and terminal operations add a significant amount of fine particulate matter (PM2.5) pollution to urban areas, more so than other freight or passenger trains, according to a study conducted in Richmond, California, by the University of California, Davis.
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Research from experts at City, University of London's Department of Sociology and Criminology suggests that although women students feel largely safe while on campus, universities have a responsibility that extends beyond campus and encompasses surrounding areas and commuter routes into and out of study areas.
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In a review of more than three decades' worth of studies that examine support for, or opposition to, policies with racial equity implications, a Cornell-led research group found that more research on messaging that includes the voices of historically marginalized people is necessary in the push toward equity.
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Studies show that some species may require breeding in captivity within the next 200 years to avoid extinction. This reality places heavy importance on the reintroduction practices used to successfully transfer species from captivity to the wild. A new study from George Mason University looks at some of the most popular conservation techniques and identifies which have the highest likelihood of su
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New research by Virginia Tech scientists shows that sections of the Chesapeake Bay are sinking at rates of nearly a quarter an inch—or 7 millimeters—a year. Further, up-to-date knowledge of where the ground in the Chesapeake Bay area is sinking and by how much is not included in the official planning maps that authorities use to assess the local flooding risk from rising sea levels, the researcher
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Future Proofing Facing an influx of ChatGPT imitators, OpenAI is looking to specifically trademark the "GPT" part of its name, TechCrunch reports . It's an eyebrow-raising decision, given the company's non-profit and open source — hence "Open" — roots. The initialism-turned-suffix, which stands for Generative Pre-trained Transformer, has quickly become synonymous with AI chatbots looking to capit
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Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide
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Studies show that some species may require breeding in captivity within the next 200 years to avoid extinction. This reality places heavy importance on the reintroduction practices used to successfully transfer species from captivity to the wild. A new study from George Mason University looks at some of the most popular conservation techniques and identifies which have the highest likelihood of su
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Researchers from Sebastian Zoll's group at IOCB Prague determined the first cryo-EM structures of a surface receptor of the human-infective parasite Trypanosoma brucei gambiense in complex with human complement factor C3 in different conformations. This provides the structural basis to understand how the parasite escapes the immune response at an early stage of infection.
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Researchers from Sebastian Zoll's group at IOCB Prague determined the first cryo-EM structures of a surface receptor of the human-infective parasite Trypanosoma brucei gambiense in complex with human complement factor C3 in different conformations. This provides the structural basis to understand how the parasite escapes the immune response at an early stage of infection.
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Nature, Published online: 27 April 2023; doi:10.1038/d41586-023-01454-7 The failure of the ispace lunar lander highlights the challenges, in particular for nascent private companies.
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Nature, Published online: 27 April 2023; doi:10.1038/d41586-023-01445-8 Machine-generated data sets have the potential to improve privacy and representation in artificial intelligence, if researchers can find the right balance between accuracy and fakery.
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A programmer is building chatbots with opposing political views to make a point about biased AI. He’s also planning a centrist bot to bridge the divide.
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A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of aging at the molecular level. They found that the process of reading genetic information does not run as smoothly in older individuals as it does in younger ones.
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When a cell is getting ready to divide, it needs to duplicate its DNA, which is divided among its chromosomes, and arrange the chromosomes so that each new cell gets one complete set. If the chromosomes get sorted incorrectly, the resulting cells with the wrong number or set can become dysfunctional, or even cancerous.
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Using the Neutron Star Interior Composition Explorer (NICER) onboard the International Space Station (ISS), an international team of astronomers has detected millihertz quasi-periodic oscillations from a low-mass X-ray binary known as 4U 1730–22. The finding was reported in a paper published March 29 in the Monthly Notices of the Royal Astronomical Society.
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The relentless hype surrounding generative AI in the past few months has been accompanied by equally loud anguish over the supposed perils — just look at the open letter calling for a pause in AI experiments. This tumult risks blinding us to more immediate risks — think sustainability and bias — and clouds our ability to appreciate the real value of these systems: not as generalist chatbots, but
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A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of aging at the molecular level. They found that the process of reading genetic information does not run as smoothly in older individuals as it does in younger ones.
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Misguided introduction of alien predator saw partula snails driven from their habitat – but zoos have reared new populations When French Polynesia was overrun by the invasive African giant land snail , another alien species, the predatory rosy wolf snail, was introduced to solve the problem. Unfortunately the rosy wolf snail devoured tiny, endemic partula snails instead, hunting down the scent of
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Blue Skies Twitter users are clamoring to get an invite to former Twitter CEO Jack Dorsey's decentralized Twitter alternative Bluesky. A quick search reveals countless accounts giving away or begging for invites. The app, now available on both Android and iOS , is only accepting new users via either a waitlist or a gifted invite code from a friend who's already on the platform. And the hype surro
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Tiny pores in the cell nucleus play an essential role for healthy aging by protecting and preserving the genetic material. A team from the Department of Theoretical Biophysics at the Max Planck Institute of Biophysics in Frankfurt am Main and the Synthetic Biophysics of Protein Disorder group at Johannes Gutenberg University Mainz (JGU) has literally filled a hole in the understanding of the struc
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Once upon a time, in what is now Wyoming, the predecessors of birds, alligators, and dinosaurs roamed the range. A lizard-like creature with a beak that ate plants around 232 million years ago has been described in a paper published in the journal Diversity.
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Tiny pores in the cell nucleus play an essential role for healthy aging by protecting and preserving the genetic material. A team from the Department of Theoretical Biophysics at the Max Planck Institute of Biophysics in Frankfurt am Main and the Synthetic Biophysics of Protein Disorder group at Johannes Gutenberg University Mainz (JGU) has literally filled a hole in the understanding of the struc
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More than 3 million square kilometers of the Asian elephant's historic habitat range has been lost in just three centuries, a new report from an international scientific team led by a University of California San Diego researcher reveals. This dramatic decline may underlie present-day conflicts between elephants and people, the authors argue.
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A flexible, wearable electronic tattoo could provide a major boost in the fight against heart disease, the leading cause of death in the US. Researchers developed an ultrathin, lightweight electronic tattoo, or e-tattoo, that attaches to the chest for continuous, mobile heart monitoring outside of a clinical setting. It includes two sensors that together provide a clear picture of heart health, g
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More than 3 million square kilometers of the Asian elephant's historic habitat range has been lost in just three centuries, a new report from an international scientific team led by a University of California San Diego researcher reveals. This dramatic decline may underlie present-day conflicts between elephants and people, the authors argue.
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Many people use hydrogels without knowing it. As superabsorbents in nappies, for example, hydrogels absorb a lot of liquid. In the process, the initially dry material becomes jelly-like, but it does not wet. Some people place the swellable material on their eyeballs—soft contact lenses are also just hydrogels. The same goes for jelly and other everyday materials.
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A team of metallurgists and materials scientists at the Max-Planck-Institut für Eisenforschung GmbH has uncovered the reason for the sluggishness that occurs when attempting to use hydrogen instead of coke to make steel. In their study, reported in the journal Physical Review Letters, the group isolated the problem and offer solutions for producing steel with reduced carbon emissions.
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Starship Fire SpaceX's explosive orbital test launch of its massive Starship spacecraft left a significant mark on its surroundings. The launch left a massive crater in the company's launchpad, spitting up vast amounts of concrete and blanketing miles of South Texas' shoreline with particulate matter. Now it turns out that the test launch even lit 3.5 acres, including land belonging to the neighb
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38029-z Here the authors demonstrate that remodelling of perturbed replication forks by the exonuclease EXD2 modulates pathway choice within the Alternative Lengthening of Telomeres mechanism and identify potentially clinically important synthetic lethal interactions in ALT cancer cells.
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Early last year, entrepreneur Luke Iseman says, he released a pair of sulfur dioxide–filled weather balloons from Mexico’s Baja California peninsula, in the hope that they’d burst miles above Earth. It was a trivial act in itself, involving far less of the gas than a commercial airliner releases. But the launch was imbued with meaning, and it pushed the simmering debate over extreme climate inter
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Claw Viper vs. Hypershock full fight! #discoveryplus #battlebots Stream Full Episodes of BattleBots https://www.discoveryplus.com/show/battlebots About BattleBots: Next-generation robots from all over the globe trade blows to reign supreme. The series highlights the design and build of each robot, bot-builder backstories and the pursuit of the BattleBots championship. Subscribe to Discovery: http
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Electrification is a key part of the transition to renewable energy, and phasing out combustion engine vehicles will be a significant piece of that transition. Despite subsidies and tax breaks around electric vehicles in the US, the cars haven’t taken over a large percentage of market share yet, perhaps because their sticker price is still higher than that of gas-powered cars. Zooming out to the
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A 2021 paper has got physicists discussing whether our inability to use classical physics to describe reality on a quantum scale is a human failing – and what proof is necessary to show that the world really is quantum mechanical, says Chanda Prescod-Weinstein
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In a small study, intravenous mistletoe extract shows promise as a cancer therapy. While the phase I trial was meant to evaluate the drug’s safety, the researchers also documented improved quality of life and some disease control among study participants with advanced and treatment-resistant cancers. Mistletoe extract has been widely used to support cancer therapy and improve quality of life, but
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A new report documents the difficult post-layoff job search and working conditions of hundreds of California fossil fuel workers in the aftermath of the 2020 closure of the Marathon Martinez oil refinery in Contra Costa County, California. The report , from the University of California, Berkeley Labor Center, is case study of the perils and needs of workers in the nation’s changing energy landsca
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Anomalies In mostly overlooked testimony, a ranking Pentagon official explained to Congress just how strange the military's UFO videos can be. As Fox News reports , Dr. Sean Kirkpatrick, the director of the Pentagon's All-domain Anomaly Resolution Office, told a Senate subcommittee that although the Defense Department hasn't yet found "credible evidence" of extraterrestrial life, there were still
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Machine learning models are incredibly powerful tools. They extract deeply hidden patterns in large data sets that our limited human brains can’t parse. These complex algorithms, then, need to be incomprehensible “black boxes,” because a model that we could crack open and understand would be useless. Right? That’s all wrong, at least according to Cynthia Rudin, who studies interpretable machine..
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Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie International Edition has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode
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Methanol is a potential feedstock for biomanufacturing since it's easily obtained in an environmentally friendly manner. But it is still challenging to construct a microbial cell factory for methanol-based bioproduction due to the toxicity of methanol and its complex cellular metabolism.
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Artificial intelligence can generate poems and essays, create responsive game characters, analyze vast amounts of data and detect patterns that the human eye might miss. Imagine what AI could do for drug discovery, traditionally a time-consuming, expensive process from the bench to the bedside.
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In the summer of 2022, over 20,000 excess deaths across Spain, France, Germany and Great Britain were suggested to have been linked to extremely hot weather. In the context of global warming where climate models point to the fact that extreme heat waves are likely to increase both in frequency and magnitude, preventive measures and adequate communication of dangerous conditions take on special rel
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Iron oxide nanoparticles are often used in medical technology as contrast agents for magnetic resonance imaging or as transport agents for drugs in the bloodstream, for example in tumor therapy. For these applications, the nanoparticles have to be biocompatible and superparamagnetic. Thus, they must be strongly magnetizable in a magnetic field and also must lose their magnetization when the magnet
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Ammonia (NH3) is one of the most widely produced chemicals in the world, with production at more than 187 million tons in 2020. About 85% of it is used to produce nitrogenous fertilizers, while the rest is used for refining petroleum, manufacturing a wide range of other chemicals, and creating synthetic fibers such as nylon. However, all this comes at a high energy cost.
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The real problem with space is there’s not enough of it—at least not when it comes to places to put people. With billionaires funding their own space programs and investors pouring cash into new start-ups aimed at building a true space economy, millions of humans may end up working and living away from Earth in a century or two. If that happens, all of those people will need somewhere to live. Bu
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Researchers at Tokyo Tech have discovered hidden chemical order of the Mo and Nb atoms in disordered Ba7Nb4MoO20, by combining state-of-the-art techniques, including resonant X-ray diffraction and solid-state nuclear magnetic resonance. This study provides valuable insights into how a material's properties, such as ionic conduction, can be heavily influenced by its hidden chemical order. These res
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Looking at the most-streamed movies or television shows on any given streaming service, it would be easy to assume that serial killers lurk behind every corner. The stories of Jeffrey Dahmer, Ted Bundy and the Boston Strangler still loom large––even if the likelihood that you'll encounter another Zodiac Killer has never been lower.
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A new paper provides insights on one of the most important factors in the Southern Oceanic carbon cycle, the "biological pump," where carbon is utilized by organisms at the surface and transferred to ocean depths, away from contact with the atmosphere. The study, authored by scientists from NOAA's Pacific Marine Environmental Laboratory and the University of Hawaiʻi at Mānoa, was published in PNAS
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Parental leave for fathers can decrease sexist attitudes and gender bias, according to new research. The researchers, including Jonathan Homola, an assistant professor of political science at Rice University, were interested in how parental leave for nontraditional caregivers affects individuals’ deeply ingrained attitudes about stereotypical gender roles and sexism—which can have adverse consequ
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Ammonia has been in the news because of its suitability as a hydrogen carrier and fuel, in addition to being a vital ingredient in fertiliser. Existing distribution networks and the ease of turning ammonia gas into a liquid make ammonia a cost-effective way to transport renewable energy. For a given volume, ammonia—a molecule made up of three hydrogen atoms and one nitrogen atom—carries about 50%
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On November 30 2022, OpenAI launched the AI chatbot ChatGTP, making the latest generation of AI technologies widely available. In the few months since then, we have seen Italy ban ChatGTP over privacy concerns, leading technology luminaries calling for a pause on AI systems development, and even prominent researchers saying we should be prepared to launch airstrikes on data centres associated with
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Want to stay current with Arthur’s writing? Sign up to get an email every time a new column comes out. K indness and niceness , though both excellent personal qualities, are not the same thing. The former is to be good to others; the latter is about being pleasant. They don’t even have to go together. Some say, for example, that New Yorkers are kind but not nice (“Your tire is flat, you moron—han
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Supreme Court Justice Clarence Thomas has spent two decades taking some very fancy vacations with the immensely rich conservative donor Harlan Crow, who also allows Thomas’s mother to live rent-free on property he bought for a very generous price from Thomas almost a decade ago. Those revelations arrived in reports from ProPublica, Slate , and CNN over the past two weeks. Other outlets had previo
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O f the roughly 1,000 people who have been charged for their participation in the January 6, 2021, assault on the Capitol, nearly a quarter were indicted alongside a relative or romantic partner. All sorts of other close personal relationships run through the indictments: the two roommates from Ohio who have known each other since they were kids, the three high-school buddies from North Carolina,
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A bout a decade ago, the social psychologist Sara Konrath led a study that yielded some disturbing results. As a researcher at Indiana University, she’d already found that narcissism rates seemed to be increasing among Americans, and empathy decreasing; that was a combination that didn’t bode well, she feared, for the quality of people’s relationships. So she decided to look more deeply into the
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38160-x DNA polymerase 1 (POLD1) has an important role in DNA damage repair and is frequently upregulated in cancer. Here, the authors report a non-canonical role of POLD1 wherein it stabilises MYC protein, creating a positive feedback loop with POLD1 expression and driving bladder cancer progression and metastasis.
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38118-z The cell interior is organized by diverse membrane-less condensates. Here, the authors reveal that the densities of certain condensates are surprisingly low, similar to the surrounding protoplasm and driven by cellular RNA as well as the crowded milieu.
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38156-7 Fear of missing neonatal sepsis has led to early in life antibiotic administration, even without culture-proven sepsis. Here, the authors discuss the potential impact on antimicrobial resistance, and chronic disease later in life, due to effect on the developing microbiome, suggesting a factual based approach i
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This is today’s edition of The Download , our weekday newsletter that provides a daily dose of what’s going on in the world of technology. America’s first IVF baby is pitching a way to pick the DNA of your kids Elizabeth Carr is head of commercial development at Genomic Prediction, a genetic testing startup that says it will assess embryos created in IVF clinics for their future chance of common
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Nature, Published online: 27 April 2023; doi:10.1038/d41586-023-01416-z Insights from mudskippers suggest that blinking is an adaptation to emerging from the sea.
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I’m really excited about the recent developments in artificial intelligence (AI) and their potential as powerful tools. I am also concerned about unintended consequences. As with any really powerful tool, there is the potential for abuse and also disruption. But I also think that the recent calls to pause or shutdown AI development, or concerns that AI may become conscious , are misguided and ver
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-37335-w Despite advances in additive manufacturing of piezoceramics, resultant transducers generally suffer from high porosity, weak piezoelectric responses, and limited geometry. Here, authors report the design and printing of fully packaged freeform ultrasonic transducers capable of traveling inside mm-sized channels
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Vissa måste få fortsätta köra bil som de alltid gjort, annars är det orättvist. Ungefär så lyder argument ofta när politiker diskuterar omställningen till ett fossilfritt samhälle ur rättvisesynvinkel. Och det är inte särskilt konstruktivt. Det menar SLU-forskare som har synat riksdagsdebatter. Inlägget dök först upp på forskning.se .
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38098-0 Cell-free genetically encoded biosensors have been developed to detect small molecules and nucleic acids, but they have yet to be reliably engineered to detect proteins. Here the authors develop an automated platform to convert protein-binding RNA aptamers into riboswitch sensors that operate within low-cost ce
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JPMorgan Chase & Co unveiled ChatGPT artificial intelligence model to decode Federal Reserve System (FRS) messages and identify potential trading signals. The company’s economists have developed a special Hawk-Dove index for forecasting and uploaded to the neural network database all the speeches of the heads of the Fed and central bankers over the past 25 years. Although the application of artif
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On January 16, inspectors from an environmental agency in western Colombia made some troubling findings . At a U.S.-funded facility supposed to be doing cutting-edge malaria research, researchers were keeping dozens of monkeys in dirty cages in poorly ventilated, over-lit enclosures. Several animals were smeared with feces. Some looked sick, and one was missing an eye. A fetid smell hung in the a
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This article is from The Spark, MIT Technology Review’s weekly climate newsletter. To receive it in your inbox every Wednesday, sign up here. We’re gathered here today to commemorate the demise of a towering figure in the energy world: nuclear power in Germany. Born: June 16, 1961 . Died: April 15, 2023. Just a decade ago, Germany was using nuclear power to meet about a quarter of its electricity
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-37988-7 African Trypanosomes have developed elaborate immune evasion mechanisms. Here, the authors present the cryoelectron microscopy structures of a trypanosome surface receptor with human complement C3 and C3b, revealing several modes of complement interaction.
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38194-1 Bioaerosol can cause the spread of disease, but current removal systems are easily blocked and often cannot deactivate the bioaerosol. Here, the authors report a method for bioaerosol removal and deactivation using a bioinspired photocatalyst capable of capturing airborne bacteria.
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-37568-9 The response to checkpoint immunotherapy within bladder cancer patients is highly variable. Here, the authors use RNA-seq, ATAC-seq and digital spatial profiling of pre- and post-treatment samples from the PURE01 trial to identify subtypes associated with treatment response.
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Life in the ocean's "twilight zone" could decline dramatically due to climate change, new research suggests. The twilight zone (200m to 1,000m deep) gets very little light but is home to a wide variety of organisms and billions of tonnes of organic matter.
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Elizabeth Carr is head of commercial development at Genomic Prediction, a New Jersey genetic testing startup that says it will assess embryos created in IVF clinics for their future chance of common diseases and then rank them, so parents can pick the one with the best future. It’s a controversial area that has some critics anguishing over the prospect of consumer eugenics. The American College o
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Man talar ibland om att forskning är som att lägga pussel. Ett av dessa gigantiska forskningspussel är kroppens proteiner – närmare 90 000 pusselbitar att hålla reda på. Lunds universitets magasin träffar tre proteinprofessorer för att bena ut varför de är så entusiastiska över proteinerna och hur de arbetar för att få ordning på proteiner som krånglar i kroppen.
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In our government/NGO section this week, Brown University’s Climate and Development Lab report Discourses of Climate Delay in the Campaign Against Offshore Wind: A Case Study from Rhode Island applies earlier work by Lamb (Discourses of Climate Delay) and Cook (FLICC taxonomy) to put the bright lights on a organization attempting to fossilize energy supplies, finding archetypal examples of both s
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Preliminary studies indicate that monthly cash payments to families — implemented as part of the short-lived 2021 expansion of the child tax credit — helped keep millions of kids out of poverty. My collaborative research suggests the policy may have also saved some of them from abuse.
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A new paper in FEMS Yeast Research reveals the possible origin story of lager beers. Using historical records and contemporary phylogenomics research, investigators here show where lagers likely first originated: at the court brewery (Hofbräuhaus) of Maximilian the Great, elector of Bavaria, in Munich in 1602.
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I was wondering which one requires a stronger attention from a cognitive science perspective? Is one more complex than the other? Also, in terms of listening to an audio book vs reading a book which one is better for verbal fluency. submitted by /u/Distractedfool [link] [comments]
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Researchers have developed a new mining technique which uses microbes to recover metals and store carbon in the waste produced by mining. Adopting this technique of reusing mining waste, called tailings, could transform the mining industry and create a greener and more sustainable future.
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Climate change is here, and scientists continue to discover new ways that the world around us is changing. In a new study published in the May issue of the Journal of Hydrology, DRI researchers show that altered weather patterns are impacting stream flows across the country, with implications for flooding, drought, and ecosystems.
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Nature Communications, Published online: 27 April 2023; doi:10.1038/s41467-023-38039-x Ebrahimi and Samanta review the key advances in the chemical and structural modification of proteins that have enabled their rise as indispensable tools in medicine and outline emerging protein engineering strategies that can potentially unlock structures with improved therapeutic properties.
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The environmental law charity ClientEarth and 13 other groups headed into a Flemish court this week in an effort to stop Ineos building a petrochemical plant that would be the biggest project of its kind in Europe for 30 years. Madeleine Finlay hears from correspondent Sandra Laville about how plastics are made, the environmental and health impacts of the process and what needs to be done to get
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The environmental law charity ClientEarth and 13 other groups headed into a Flemish court this week in an effort to stop Ineos building a petrochemical plant that would be the biggest project of its kind in Europe for 30 years. Madeleine Finlay hears from correspondent Sandra Laville about how plastics are made, the environmental and health impacts of the process and what needs to be done to get a
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Investigators have created computer-generated models to bridge the gap between 'test tube' data about neurons and the function of those cells in the living brain. Their study could help in the development of treatments for neurological diseases and disorders that target specific neuron types based on their roles.
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Astronomers have observed, in one image, the shadow of the black hole at the center of the galaxy Messier 87 (M87) and the powerful jet expelled from it. Thanks to this new image, astronomers can better understand how black holes can launch such energetic jets.
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Engineers designed a nanoparticle sensor that could enable early diagnosis of cancer with a simple urine test. The sensors, which can detect many cancerous proteins, could also be used to distinguish the type of a tumor or how it is responding to treatment.
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What's good for the Black-backed Woodpecker is good for restoration of burned California forests. The birds' unique relationship with fire underpins the latest research into improved post-fire management. A study describes a new tool that factors in how fires burn into forest management decisions and turns science into action for wildlife conservation.
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The greenhouse gas carbon dioxide can be converted into useful hydrocarbons by electrolysis. The design of the electrolysis cell is crucial in this process. The so-called zero-gap cell is particularly suitable for industrial processes. But there are still problems: The cathodes clog up quickly.
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A new study has shown that overuse of antimicrobials in livestock production can drive the evolution of bacteria more resistant to the first line of the human immune response. Bacteria that had evolved resistance to colistin, an antimicrobial widely used in farming, also showed resistance to compounds that are key components of human and animal immune systems. The results indicate that farmed pigs
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In the late 1980s, the fortunes of Nick Navarro, the sheriff of Broward County, Florida, were on the rise. Elected in 1984 and on his way to nearly tripling his agency’s budget, he was also demonstrating a flair for dealing with the media—“P. T. Barnum with a Cuban accent,” said one South Florida defense lawyer . Navarro and his office starred in the inaugural season of Cops , the pioneering Fox
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. Tucker Carlson is, for now, off the air and lying low. But his rapid slide from would-be journalist to venomous demagogue is the story of a generation of political commentators who found that inducing
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On the first day of the rest of my life, I went to Bed Bath & Beyond. It was a rainy spring Monday in 2011, and like generations of optimistic 20-somethings before me, I had just washed up on New York City’s shores with two bulging suitcases and the keys to a tiny, dingy apartment. I had spent most of the previous year saving every cent possible so that I could rent and furnish a bedroom in an un
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From the department of extremely cool innovations, design publication Core77 reports that the San Francisco-based firm Augmental Technologies has invented a Bluetooth mouse designed to be worn inside a user's mouth. Per Core77 , the device — which is essentially worn like a mouthguard — is dubbed the MouthPad, and was created as a means to help paraplegics better navigate their computers, smartph
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Over a span of roughly two months, NBC News reports , Twitter and law enforcement failed to intervene while a 13-year-old boy was being publicly groomed by a 26-year-old adult on the social media platform. The exchanges eventually led to an abduction, according to prosecutors, with the boy reportedly being driven across state lines and sexually assaulted repeatedly. All the while, the suspect was
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In cereal crops, the number of new leaves each plant produces is used to study the periodic events that constitute the biological life cycle of the crop. The conventional method of determining leaf numbers involves manual counting, which is slow, labor-intensive, and usually associated with large uncertainties because of the small sample sizes involved. It is thus difficult to get accurate estimat
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In cereal crops, the number of new leaves each plant produces is used to study the periodic events that constitute the biological life cycle of the crop. The conventional method of determining leaf numbers involves manual counting, which is slow, labor-intensive, and usually associated with large uncertainties because of the small sample sizes involved. It is thus difficult to get accurate estimat
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Sand filters are commonly applied in drinking water treatment and can efficiently remove suspended solids, organic matter, and microorganisms from source water. During the process, particulate matter and microbes can attach to filter sands and develop a thick biofilm in both rapid and slow sand filters. To prevent clogging and restore pollutant removal efficiency, backwashing using air, water, or
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Bacteria can be quite aggressive. Armed with an impressive array of mechanical and biochemical weapons, they don't mess around when it comes to combating their foes. Notable among these armaments is the Type VI Secretion System (T6SS), a membrane-embedded nanomachine found in many gram-negative bacteria. The needle-like system helps bacteria antagonize prokaryotic and eukaryotic cells by injecting
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Increasing either temperature or nutrients can hurt ecosystems by destabilizing food webs, which are all of the interconnected food chains that make communities behave the way they do. When temperature and nutrients increase together, however, ecosystems sometimes behave in unexpected ways.
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The primary structure that will serve as the "bones" of NASA's Nancy Grace Roman Space Telescope has moved into the big clean room at NASA's Goddard Space Flight Center in Greenbelt, Maryland. The spacecraft bus, Roman's primary support element, will now be built upon this skeletal framework. When it launches by May 2027, Roman will help unravel the secrets of dark energy and dark matter, search f
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Molecular aggregates are clusters of small molecules held together by relatively weak forces believed to be originating from electronic interactions between the molecules. Owing to their exceptional photophysical properties, molecular aggregates find unique applications in many areas of technology and continue to be a subject of intense research. In fact, researchers have utilized molecular aggreg
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A George Washington University study offers new insights into why human cultures become more complex over time. The study finds that people combine and generalize socially acquired knowledge over time, resulting in new and more complex knowledge. The ability to combine and generalize socially learned knowledge appears to occur prior to formal schooling and may represent a unique feature of human i
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A new paper in the Journal of Survey Statistics and Methodology indicates that the methods researchers use to report on analyses of survey data vary widely, and frequently contain mistakes. Publications containing these incorrect analyses yield results that can misinform policymakers, researchers, and practitioners. The researchers here propose new standards to improve the reporting of analyses us
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Bacteria can be quite aggressive. Armed with an impressive array of mechanical and biochemical weapons, they don't mess around when it comes to combating their foes. Notable among these armaments is the Type VI Secretion System (T6SS), a membrane-embedded nanomachine found in many gram-negative bacteria. The needle-like system helps bacteria antagonize prokaryotic and eukaryotic cells by injecting
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Welcome to Up for Debate. Each week, Conor Friedersdorf rounds up timely conversations and solicits reader responses to one thought-provoking question. Later, he publishes some thoughtful replies. Sign up for the newsletter here. Question of the Week I’m still making my way through your many emails about trans issues ; I expect the roundup to go out next week. Meanwhile, feel free to keep corresp
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Revelations and research over the last few years have shed light on how Instagram may negatively affect its youngest users. The most popular social media platform among 13- to 21-year-olds in America, Instagram was designed to connect people with shared interests. However, recent research has pointed to the use of social media as possibly contributing to a rise in mental health and eating disorder
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The COVID-19 pandemic highlighted the importance of closely monitoring viruses that could infect humans. In the early stages of the pandemic, Timothée Poisot and his colleagues were already developing an algorithm for predicting mammal-virus interactions.
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What's It Gonna Be? Publicly traded cryptocurrency exchange Coinbase has filed a lawsuit against the Securities and Exchange Commission (SEC), CNBC reports . With its suit, Coinbase is urging the regulatory arm to publicize its response to a separate petition, which it filed back in July 2022, requesting the SEC to "propose and adopt rules to govern the regulation of securities that are offered a
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China has scored consecutive good harvests for years running, but there has been a problem of agricultural production that emphasizes weight rather than quality. The main manifestation is the long-term and high-intensity use of land resources and the massive application of mineral fertilizers and pesticides to meet the demand for increased production.
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Hundreds of millions of years before the evolution of animals with segmented bodies, jointed skeletons or appendages, soft-bodied invertebrates like sea slugs ruled the seas. A new study finds parallels between the brain architecture that drives locomotion in sea slugs and that of more complex segmented creatures with jointed skeletons and appendages.
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A brand's communication through social media posts is all the more effective the more it is in line with the image and values the public associates with the brand. This is the subject of a recent article in the Journal of Interactive Marketing by Sara Valentini of the Bocconi University, Milan, co-written with Elisa Montaguti of the University of Bologna and Federica Vecchioni, data scientist at R
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Do you want to create a society through design where people with and without disabilities can live together as they are? Prof Mao Kudo of the Department of Media Design hopes that her research results are not just used to research further but that they become rooted in the fabric of society in transportation systems, and educational and public facilities. With her paper published in Visual Languag
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A versatile new foam material developed by researchers at the University of Georgia could significantly reduce health care-related infections caused by implanted medical devices—or drastically improve cleanup efforts following environmental disasters like oil spills.
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It has long been a dream for Earth scientists to have a numerical model that can better represent compound multiple-scale processes in the real-world Earth system. Apart from requiring deep understanding on physics of geo-fluid motions, developing such a model demands interdisciplinary advancement in the Earth sciences and high-performance supercomputing as well as software engineering.
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Per- and polyfluoroalkyl substances (PFAS) are considered to be forever chemicals. Many are toxic; others are highly mobile or accumulate in the food chain. However, all are extremely persistent and are spread throughout the environment. The contamination hot-spots of the PFAS can be proven only with a great deal of effort. This is why indicators are needed.
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For the rational design of new material compounds, it is important to understand the mechanisms underlying their synthesis. Analytical techniques such as nuclear magnetic resonance and spectroscopy are usually employed to study such mechanisms in molecular reactions. However, reaction pathways governing the formation of solid-state crystalline compounds remain poorly understood.
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Ciliated protists represent one of the most primitive lineages of eukaryotes, with nuclear dimorphism, a distinctive sexual process (conjugation), and extensive genome rearrangements. Sessilida, among diverse ciliate lineages, is the only group containing members living a colonial lifestyle, i.e., many cells are 'connected' by their stalk and a colony is formed through binary fission.
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in a world where ecological and societal collapse is imminent, why do people still bring children into the world? they will know nothing but suffering and misery. submitted by /u/EvaTheWarlock [link] [comments]
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Imagine that we create an open world for user to load their painting things being created by multimodal format into the extendable world. Unlike the fixable metaverse, we provide the interface between all kinds of format for all kinds of user wanting join. So, I should first build a way to transmit all kinds of format with each other. As an individual player, I should develop an easy platform fo
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Harry Belafonte, the singer, actor, and activist, passed away yesterday at the age of 96. Belafonte was celebrated not only as a gifted performer but as a trailblazer in the entertainment industry, a fierce defender of civil rights, and an inspiration to many. Jason Heller writes more on his lasting impact in “ How Harry Belafonte Transformed American Music .” Gathered below are images from Belaf
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Abstract Dysfunction of either the right or left ventricle can lead to heart failure (HF) and subsequent morbidity and mortality. We performed a genome-wide association study (GWAS) of 16 cardiac magnetic resonance (CMR) imaging measurements of biventricular function and structure. Cis- Mendelian randomization (MR) was used to identify plasma proteins associating with CMR traits as well as with a
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Abstract We report 21 families displaying neurodevelopmental differences and multiple congenital anomalies while bearing a series of rare variants in mitogen-activated protein kinase kinase kinase kinase 4 ( MAP4K4 ). MAP4K4 has been implicated in many signaling pathways including c-Jun N-terminal and RAS kinases and is currently under investigation as a druggable target for multiple disorders. U
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Abstract Understanding the nature of strongly correlated states in flat-band materials (such as moiré heterostructures) is at the forefront of both experimental and theoretical pursuits. While magnetotransport, scanning probe, and optical techniques are often very successful in investigating the properties of the underlying order, the exact nature of the ground state often remains unknown. Here,
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Abstract Aberrant AKT activation occurs in a number of cancers, metabolic syndrome, and immune disorders, making it an important target for the treatment of many diseases. To monitor spatial and temporal AKT activity in a live setting, we generated an Akt-FRET biosensor mouse that allows longitudinal assessment of AKT activity using intravital imaging in conjunction with image stabilization and o
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Abstract Although most mammals heal injured tissues and organs with scarring, spiny mice ( Acomys ) naturally regenerate skin and complex musculoskeletal tissues. Now, the core signaling pathways driving mammalian tissue regeneration are poorly characterized. Here, we show that, while immediate extracellular signal-regulated kinase (ERK) activation is a shared feature of scarring ( Mus ) and rege
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Abstract Breast cancer has been shown to be resistant to immunotherapies. To overcome this challenge, we developed an active immunotherapy for personalized treatment based on a smart nanovesicle. This is achieved by anchoring membrane-bound bioactive interleukin 2 (IL2) and enriching T cell–promoting costimulatory factors on the surface of the dendritic cell–derived small extracellular vesicles.
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Abstract In marine systems, the availability of inorganic phosphate can limit primary production leading to bacterial and phytoplankton utilization of the plethora of organic forms available. Among these are phospholipids that form the lipid bilayer of all cells as well as released extracellular vesicles. However, information on phospholipid degradation is almost nonexistent despite their relevan
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Abstract Musicianship can mitigate age-related declines in audiovisual speech-in-noise perception. We tested whether this benefit originates from functional preservation or functional compensation by comparing fMRI responses of older musicians, older nonmusicians, and young nonmusicians identifying noise-masked audiovisual syllables. Older musicians outperformed older nonmusicians and showed comp
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Abstract Amine-targeting reactions that work under biocompatible conditions or in water are green processes that are extremely useful for the synthesis of functional materials and biotherapeutics. Unfortunately, despite the usefulness of this reaction, there are very few good amine-specific click methods reported thus far. Here, we report an amine-specific click reagent using alkynone β-trifluoro
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Abstract With remote magnetic steering capabilities, magnetically actuated guidewires have proven their potential in minimally invasive medical procedures. Existing magnetic steering strategies, however, have been limited to low magnetic fields, which prevents the integration into medical systems operating at ultrahigh fields (UHF), such as magnetic resonance imaging (MRI) scanners. Here, we pres
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Abstract Models that estimate rates of energy flow in complex food webs often fail to account for species-specific prey selectivity of diverse consumer guilds. While DNA metabarcoding is increasingly used for dietary studies, methodological biases have limited its application for food web modeling. Here, we used data from dietary metabarcoding studies of zooplankton to calculate prey selectivity
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Abstract By the fine manipulation of the exceptional long-range germanium-telluride (Ge─Te) bonding through charge transfer engineering, we have achieved exceptional thermoelectric (TE) and mechanical properties in lead-free GeTe. This chemical bonding mechanism along with a semiordered zigzag nanostructure generates a notable increase of the average zT to a record value of ~1.73 in the temperatu
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Abstract During T cell activation, the transmembrane adaptor protein LAT (linker for activation of T cells) forms biomolecular condensates with Grb2 and Sos1, facilitating signaling. LAT has also been associated with cholesterol-rich condensed lipid domains; However, the potential coupling between protein condensation and lipid phase separation and its role in organizing T cell signaling were unk
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Abstract Higher-order optical harmonics entered the realm of nanostructured solids being observed recently in optical gratings and metasurfaces with a subwavelength thickness. Structuring materials at the subwavelength scale allows us toresonantly enhance the efficiency of nonlinear processes and reduce the size of high-harmonic sources. We report the observation of up to a seventh harmonic gener
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Abstract The shallower portions of subduction zone megathrust faults host Earth’s most hazardous tsunamigenic earthquakes, yet understanding how and when they slip remains elusive because of challenges making seafloor observations. We performed Global Navigation Satellite System Acoustic seafloor geodetic surveys before and ~2.5 months after the 29 July 2021 M w (moment magnitude) 8.2 Chignik, Al
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Abstract What makes certain images more memorable than others? While much of memory research has focused on participant effects, recent studies using a stimulus-centric perspective have sparked debate on the determinants of memory, including the roles of semantic and visual features and whether the most prototypical or atypical items are best remembered. Prior studies have typically relied on con
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Abstract The higher-order assembly of Bin-amphiphysin-Rvs (BAR) domain proteins, including the FCH-BAR (F-BAR) domain proteins, into lattice on the membrane is essential for the formation of subcellular structures. However, the regulation of their ordered assembly has not been elucidated. Here, we show that the higher ordered assembly of growth-arrested specific 7 (GAS7), an F-BAR domain protein,
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Abstract Nononcogenic somatic mutations are thought to be uncommon and inconsequential. To test this, we analyzed 43,693 National Heart, Lung and Blood Institute Trans-Omics for Precision Medicine blood whole genomes from 37 cohorts and identified 7131 non-missense somatic mutations that are recurrently mutated in at least 50 individuals. These recurrent non-missense somatic mutations (RNMSMs) ar
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Abstract The perfluorosulfonic acid (PFSA) proton exchange membrane (PEM) is the key component for hydrogen fuel cells (FCs). We used in situ synchrotron scattering to investigate the PEM morphology evolution and found a “stream-reservoir” morphology, which enables efficient proton transport. The short-side-chain (SSC) PFSA PEM is fabricated under the guidance of morphology optimization, which de
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Abstract Crystalline photodiodes remain the most viable infrared sensing technology of choice, yet the opacity and the limitation in pixel size reduction per se restrict their development for supporting high-resolution in situ infrared images. In this work, we propose an all-organic non-fullerene–based upconversion device that brings invisible infrared signal into human vision via exciplex cohost
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