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Wake Up Ever since going into hibernation in May 2022 to wait out a bitterly cold winter, China's Mars rover Zhurong has remained in its deep slumber. That's despite expectations of having it wake up and resume its exploration of the Martian surface in December, leading to questions about whether the mission is now over. Chinese officials have stayed strikingly quiet since then, refusing to shed
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Bad news for people who love fried food: French fries are not only bad for your physical health, but detrimental to your mental well-being as well, according to new research. In a new study published in the journal Proceedings of the National Academy of Sciences , a team of researchers found a link between eating fried potatoes and having anxiety or depression after analyzing data collected from
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Effective weed control is crucial in agriculture to ensure high crop productivity. It entails the careful separation of weeds from crops before herbicides are sprayed in the fields. In simple terms, the goal of weed control is to remove the weeds while ensuring that the crop are not harmed. Traditional weed control methods have several drawbacks, such as crop contamination, herbicide waste, and po
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Effective weed control is crucial in agriculture to ensure high crop productivity. It entails the careful separation of weeds from crops before herbicides are sprayed in the fields. In simple terms, the goal of weed control is to remove the weeds while ensuring that the crop are not harmed. Traditional weed control methods have several drawbacks, such as crop contamination, herbicide waste, and po
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The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks. The cell membrane encloses the cell interior, but is constantly remodeled, for example, due to membrane budding, invagination, or fusion processes. This also involves various proteins that were long assumed to be present exclusively or
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The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks. The cell membrane encloses the cell interior, but is constantly remodeled, for example, due to membrane budding, invagination, or fusion processes. This also involves various proteins that were long assumed to be present exclusively or
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The explosion of two-dimensional layered materials (2DLMs) with various unique properties provides basic building blocks for van der Waals heterostructures (vdWHs). The vdWHs integrated with various stacking alignments of 2DLMs exhibit many promising functionalities in diverse fields, including electronics, optoelectronics, thermoelectrics, sensing and energy conversion and storage. In addition, t
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Scientists from The Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, together with foreign colleagues, have demonstrated that human 14-3-3 proteins, which are known for their role in replication of many viruses, bind differentially with more often mutating regulatory parts of nucleoproteins (N protein) of the SARS-CoV-2 virus.
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Twitter Alt Elon Musk may have accidentally leaked his alternate Twitter account — and it's really, really weird. The evidence so far is circumstantial, but pretty convincing. It all started when Musk tweeted a screenshot of his phone logged into Twitter, Vice reports , intended to be a showcase of the site's new subscription feature. In addition to flexing the fact that his Twitter has nearly 25
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Scientists from The Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, together with foreign colleagues, have demonstrated that human 14-3-3 proteins, which are known for their role in replication of many viruses, bind differentially with more often mutating regulatory parts of nucleoproteins (N protein) of the SARS-CoV-2 virus.
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iSpace , a private space company based in Japan, lost contact with its Hakuto-R spacecraft as it attempted to become the first private mission to land on the moon this morning. “We have to assume that we could not complete the landing on the lunar surface,” iSpace CEO and founder Takeshi Hakamada said during a livestream . “Our engineers will continue to investigate the situation, and we will upd
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Ispace loses communication with Hakuto-R lunar lander, ending a mission that began more than four months ago A Japanese startup attempting the first private landing on the moon has lost communication with its spacecraft and said that it assumes the lunar mission had failed. Ispace said that it could not establish communication with the uncrewed Hakuto-R lunar lander after its expected landing tim
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Biosensors—sensors that can detect biological samples—are powerful tools for understanding the function, composition, and structure of biochemical molecules. Biosensors are often applied for the detection of proteins and their subunits, called peptides, yielding a wide range of biomedical applications.
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Martian Mood After inspecting NASA's Mars lander data, scientists say they've figured out what lies at the heart of the Red Planet's core. In a press release about the revolutionary findings out of the University of Maryland, the geologists who made this landmark discovery say that Mars' core is made up of a gooey liquid iron alloy that's "rich in sulfur and oxygen." This hypothesis was gleaned,
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Astrophysicists have provided the most direct evidence yet that Dark Matter does not constitute ultramassive particles as is commonly thought but instead comprises particles so light that they travel through space like waves. Their work resolves an outstanding problem in astrophysics first raised two decades ago: why do models that adopt ultramassive Dark Matter particles fail to correctly predict
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By almost any historic yardstick, President Joe Biden is beginning the reelection campaign he formally announced today in a vulnerable position. His job-approval rating has consistently come in at 45 percent or less; in several recent high-quality national polls, it has dipped closer to 40 percent. In surveys, three-fourths or more of Americans routinely express dissatisfaction with the economy.
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April 25 has been set aside as World Penguin Day, a day to appreciate and consider these remarkable aquatic birds and their place in our world, as climate change and other pressures threaten their habitat and food sources, leading to significant declines in some populations. Gathered below, images of these unique creatures from across the colder parts of the Southern Hemisphere.
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Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations. In the case of influenza A, they were able to determine how the immune system fights off the virus using a sma
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Researchers develop an early warning system that combines acoustic technology with AI to immediately classify earthquakes and determine potential tsunami risk. They propose using underwater microphones, called hydrophones, to measure the acoustic radiation produced by the earthquake, which carries information about the tectonic event and travels significantly faster than tsunami waves. The computa
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Researchers develop a model to describe the interaction between a rocket plume and the surface of a planetary body in near-vacuum conditions. The computational framework takes in information about the rocket, its engines, and the surface composition and topography, as well as the atmospheric conditions and gravitational forces at the landing site, and the results can be used to evaluate the safety
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New research shows that poor air quality could be causing cognitive problems in babies and toddlers. A new study reveals an association between poor air quality in India and impaired cognition in infants under two. Without action, the negative impact on children's long-term brain development could have consequences for life.
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Pet rabbits have higher levels of the stress hormone—corticosterone—and show activity rebound when kept in small hutches with restricted exercise, new research led by the University of Bristol Vet School has found. The research highlights the importance that pairs of pet rabbits should have the freedom to exercise outside their home enclosure even when they are kept in hutches larger than the trad
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Pet rabbits have higher levels of the stress hormone—corticosterone—and show activity rebound when kept in small hutches with restricted exercise, new research led by the University of Bristol Vet School has found. The research highlights the importance that pairs of pet rabbits should have the freedom to exercise outside their home enclosure even when they are kept in hutches larger than the trad
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The barred spiral galaxy UGC 678 takes center stage in this image from the NASA/ESA Hubble Space Telescope. The spectacular galaxy lies around 260 million light-years from Earth in the constellation Pisces and is almost face on, allowing its lazily winding spiral arms to stretch across this image. In the foreground, a smaller edge-on galaxy seems to bisect the upper portion of UGC 678.
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Rice, a staple crop, is widely cultivated in China. The farmers enhance the rice yield and grain quality through nitrogen (N) fertilizers. But using them in excess negatively affects crop production and harms the environment. Therefore, determining the optimum quantity of N fertilizers for effective rice growth without any wastage is crucial.
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Deinococcus radiodurans can survive a range of harsh environments and is resistant to very high levels of ionizing and UV radiation, dehydration, cold, vacuum, and even acid. Therefore, the bacterium has unmatched potential to act as a bacterial chassis (i.e., a bacterium that carries and supports the genetic components necessary for a particular experiment or application) in synthetic biology. Fo
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In the RUBIO project, 18 partners are turning the vision of a sustainable plastics industry into reality. Their goal is to use regionally available plant residues to create versatile, sustainable products that are recyclable and biodegradable. As part of the project, the Fraunhofer Institute for Applied Polymer Research IAP is developing new types of the bioplastic polybutylene succinate (PBS) so
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Rice, a staple crop, is widely cultivated in China. The farmers enhance the rice yield and grain quality through nitrogen (N) fertilizers. But using them in excess negatively affects crop production and harms the environment. Therefore, determining the optimum quantity of N fertilizers for effective rice growth without any wastage is crucial.
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Deinococcus radiodurans can survive a range of harsh environments and is resistant to very high levels of ionizing and UV radiation, dehydration, cold, vacuum, and even acid. Therefore, the bacterium has unmatched potential to act as a bacterial chassis (i.e., a bacterium that carries and supports the genetic components necessary for a particular experiment or application) in synthetic biology. Fo
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Lost Comms Getting into space is hard — but landing on the Moon is even harder. Japanese lunar lander Hakuto-R Mission 1, developed by private space company ispace, attempted to touch down on the surface of the Moon today. But the planned landing time came and went, with mission control failing to reestablish communications. "We have not confirmed communication from the lander," a somber ispace f
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The large impact craters dotting our planet are powerful reminders that asteroids and comets strike the Earth from time to time. As often said, it's not a question of "if"; it's a matter of "when" our planet will face an impending strike from space. But an impact is one existential threat humanity is finally starting to take seriously and wrap its head around.
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The Hakuto-R lunar lander, currently in orbit around the moon, just captured a beautiful "Earthrise"-like image, and one with an interesting side note. The Mission 1 lander, from the Tokyo-based commercial company ispace, took the image during the time of the April 20 solar eclipse, where totality was visible in Australia; and so the photo includes a perfect view of the shadow of the moon passing
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For decades, the white power movement has gained steady momentum in the U.S. Kathleen Belew is an expert on the history of the white power movement and its current impact on American society and politics. Her book "Bring the War Home: The White Power Movement and Paramilitary America" examines how the aftermath of the Vietnam War led to the birth of the white power movement.
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A good way to learn psychology is to ruin two birthday parties. Take it from me: I’ve got a Ph.D. in experimental psychology, but I didn’t really understand my own field until I started showing up at strangers’ birthday parties because science told me to. And now that I’ve inadvertently wrecked multiple get-togethers, I finally know the true meaning of psychology. It happened in Atlanta, just aft
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Hope feels elusive in America right now. Suicides and fatal drug overdoses—so-called deaths of despair resulting from a seeming lack of hope—are at unprecedented levels. Mental-health problems are on the rise: A recent CDC study of teenagers found a significant increase in sadness and vulnerability to suicide over the past decade, particularly among teen girls—a trend that began well before the c
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When oil contaminates water, it creates a film that reduces oxygen levels and introduces toxic substances. This can lead to the death of aquatic plants and animals, contaminate soil, and ultimately threaten human health.
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A reputation can be damaged by a single mistake, or after months or even years of bad behavior. Organizations may turn a blind eye to such behavior by employees or business leaders, and sometimes it is tacitly enabled by a toxic culture that prioritizes an end game—profits or "winning"—over people or planet.
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Genetic markers such as fragment length polymorphisms (RFLP), simple sequence repeats (SSRs), and single-nucleotide polymorphisms (SNPs) provide unique identifiers for individual organisms. This aids the identification of significant genetic variations in plants, allowing modern plant breeding to select superior crop varieties. Next-generation sequencing (NGS) has enhanced marker-assisted selectio
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Doctors often use tongue depressors when peering in a patient's mouth and throat. But what if that flat wooden spatula could actively evaluate the patient's health? That's the premise of an ecofriendly disposable sensor, reported in Analytical Chemistry, that can check levels of glucose and other biomarkers in saliva. Researchers say the easy-to-produce device could someday help doctors assess a r
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Often left on the surfaces of a crime scene or on the clothes of an accused criminal, blood backspatter can be used as evidence for forensic scientists to reconstruct what occurred. However, the fluid dynamics at play are complicated, and neglecting the interaction between the blood and the muzzle gases from the firearm could skew the results.
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A study found that people around the world signal others for assistance every couple of minutes. The research, which examined behaviors in towns and rural areas in several different countries, revealed that people comply with these small requests for help far more often than they decline them. The findings suggest that people from all cultures have more similar cooperative behaviors than prior res
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Every giant was once a baby, though you may never have seen them at that stage of their development. NASA's James Webb Space Telescope has begun to shed light on formative years in the history of the universe that have thus far been beyond reach: the formation and assembly of galaxies. For the first time, a protocluster of seven galaxies has been confirmed at a distance that astronomers refer to a
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The former Fox News host didn’t just fuel far-right politics in the US. His rants have fed conspiracy theorists and extremists all over the world.
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Medication delivered by a new gel cured 100% of mice with an aggressive brain cancer, according to a new study. The striking results offer new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans. “Despite recent technological advancements, there is a dire need for new treatment strategies,” says Honggang Cui, a chemical and biomolecular engin
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Are we separate and superior to nature? This question has been a driving force behind humanity's industrialization and economic progress for centuries — but it's brought us to the brink of an ecological crisis, says filmmaker Damon Gameau. In an impassioned talk, he calls for a new story that recognizes our interconnectedness with nature and moves towards a thriving, regenerative future.
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Genetic markers such as fragment length polymorphisms (RFLP), simple sequence repeats (SSRs), and single-nucleotide polymorphisms (SNPs) provide unique identifiers for individual organisms. This aids the identification of significant genetic variations in plants, allowing modern plant breeding to select superior crop varieties. Next-generation sequencing (NGS) has enhanced marker-assisted selectio
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A new study published in Animal Cognition shows that horses living in big enclosures and in groups of at least three are better at following directional indications from humans than horses kept in individual paddocks. The results also indicate that familiarity to the human providing the indications does not matter for the horses.
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Impossible Bar With or without guardrails in place, AI-powered chatbots — like OpenAI's ChatGPT or Google's Bard — are notoriously unpredictable . Even so, the New York Times is reporting that any chatbots operating within China's digital borders must comply with the ruling Communist Party's censorship laws. Of course, with that unpredictability in mind, the jury's still out on whether or not the
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Imagine Sarah and John have been in a monogamous relationship for five years. Although they love each other, Sarah, who is bisexual, has recently started feeling an attraction to her coworker, Andrea. This has led to several sexual encounters, leaving Sarah feeling guilty. However, she has not talked to John about her feelings or experiences with Andrea.
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As genetic information carriers, nucleic acid molecules have been developed as gene therapeutic drugs. On the basis of complementary base pairing, nucleic acid can not only encode functional genes, but also precisely self-assemble into nanostructures with specific sizes and shapes. However, the innate property (encoding gene) of these DNA nanostructures has rarely been displayed for gene therapy.
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The combustion of oil, coal or natural gas produces carbon dioxide, or CO2. This notorious greenhouse gas is a major driver of global warming, but it is also a raw material. It is technically possible to convert CO2 into useful carbon compounds, a process which requires energy, water, suitable electrodes and special catalysts.
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Oceanografer har netop kortlagt godt 19.000 undersøiske bjerge på havbunden ved hjælp af radarsatellitdata. Den nye kortlægning kan bruges til udvidet minedrift på havbunden, overvågning af dybereliggende havstrømme og et varslingsværktøj for undersøiske fartøjer.
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Craft brewers are continuously upping the ante and coming up with innovative ways to make or flavor their newest beers. Now, researchers are adding a new twist of their own, speeding up the brewing process with beer-making mini-robots or 'BeerBots.' The team shows that these self-propelled, magnetic packages of yeast can make the fermentation phase go faster and cut out the need to filter the beve
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An interdisciplinary team of researchers has developed a suite of tools to estimate the total economic value of improving water quality in urban streams. The work can assist federal and state agencies charged with developing environmental regulations affecting urban ecosystems across the Piedmont Region of the United States, which stretches from Maryland to Alabama.
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Researchers have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy. The technique, called Optical Nanomotion Detection, is extremely rapid, single-cell sensitive, label-free, and requires only a basic traditional optical microscope, equipped with a camera or a mobile phone.
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Organic solar cells have a photoactive layer that is made from polymers and small molecules. The cells are very thin, can be flexible, and are easy to make. However, the efficiency of these cells is still much below that of conventional silicon-based ones. Applied physicists have now fabricated an organic solar cell with an efficiency of over 17 percent, which is in the top range for this type of
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Ignoring the interaction between wind and ocean currents can have consequences for predicting global warming, researchers report. Specifically, it can cause climate models to underestimate warming by as much as 17%, a new study shows. “The ocean plays a huge role in global warming—its currents can redistribute heat from warmer to colder regions, for instance, by moving warm water from the equator
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Mishap Investigation SpaceX's explosive orbital test flight of its Starship spacecraft, the most powerful rocket ever built, left a huge mark on its surroundings, scouring a massive crater in the ground and sending particulate matter flying for miles, far beyond the expected debris field. Without any significant diversion measures in place, Starship's Super Heavy booster tore through the company'
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On Saturday, Special Operations Forces successfully evacuated fewer than 100 U.S.-embassy personnel from Sudan. Then, in a startling break with American precedent, the State Department announced that it would not request further evacuations of trapped U.S. citizens from a country descending into violent conflict. There are currently 16,000 Americans reported in Sudan, and the U.S. embassy is in t
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Donald Trump, who is accused of rape, will likely not appear in court to defend himself against the charge. The former president declined the chance to appear at the trial that begins today, he explained through his lawyer, because of the “logistical burdens” his presence would place on the courthouse and on New York City, where the civil proceeding is taking place. It seems he does not want to b
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Authors say scientist’s role was acknowledged at the time of discovery – contrary to popular narrative In the story of how Francis Crick and James Watson discovered the structure of DNA, the popular narrative is one of skullduggery and deceit. But now researchers say there is a twist in the tale of the double helix. It has long been held that Rosalind Franklin’s X-ray diffraction image known as P
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The adage 'birds of a feather flock together' is being given new meaning in a recent study. When multiple species join a single flock, they appear to mimic each other, with spectacular results. Researchers think this counterintuitively promotes diversity.
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An international team of space scientists has found evidence suggesting that planets could have formed during the so-called "cosmic noon." In their study, reported in the journal Nature Astronomy, the group used data from the James Webb Space Telescope (JWST) to study a part of the Small Magellanic Cloud (SMC) to learn more about planet development around young stars.
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A new type of aromatic nanobelt, methylene-bridged [n]cycloparaphenylene ([n]MCPP), has been synthesized and its properties elucidated by researchers at the Institute of Transformative Bio-molecules (WPI-ITbM) at Nagoya University in Japan, in collaboration with researchers at the Università degli Studi di Salerno in Italy and the University of Nevada in the U.S.
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Catching Fire Ford was hoping its F-150 Lightning would be the next hot commodity in electric pickup trucks — but probably not like this. New footage obtained by CNBC through a Freedom of Information Act (FOIA) shows a close-up look at the February fire that burned through several F-150 Lightnings at a holding lot in Michigan, in an alarming wake up call on Ford's quality control and the severe b
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MIT engineers have designed a new nanoparticle sensor that could enable early diagnosis of cancer with a simple urine test. The sensors, which can detect many different cancerous proteins, could also be used to distinguish the type of a tumor or how it is responding to treatment.
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A distant star, dying a fiery and dramatic death, torn apart by a supermassive black hole in a forgotten corner of the sky. One of the most luminous, energetic, long-lasting transient objects didn't blaze through the night sky inspiring legends and launching civilizations. Instead, astronomers, acting as celestial supersleuths, uncovered evidence of the star's death throes where it had hidden unde
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When a lander descends toward the moon—or a rocky planet, asteroid, or comet—the exhaust plume of the rocket interacts with the surface, causing erosion and kicking up regolith particles. The resulting blanket of dusty debris can create a dangerous brownout effect, limiting visibility and potentially damaging the spacecraft or nearby equipment.
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Utmattning, ett tidigt tecken på utbrändhet, rapporterades under pandemin av nästan en femtedel av tillfrågad personal inom kvinno- och nyföddhetsvård. Det framgår av en studie från Göteborgs universitet. Inlägget Många utmattade i kvinno- och nyföddhetsvården under pandemin dök först upp på forskning.se .
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If you spend any time on the internet, you’re likely now familiar with the gray-and-teal screenshots of AI-generated text. At first they were meant to illustrate ChatGPT’s surprising competence at generating human-sounding prose, and then to demonstrate the occasionally unsettling answers that emerged once the general public could bombard it with prompts. OpenAI, the organization that is developi
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As SpaceX's Starship took to the skies last week during its inaugural launch , its Super Heavy booster inflicted untold damage to the launch pad below, blasting through layers of concrete and dredging up watery folds of the Earth. Photos of the aftermath stand as testament to the sheer forces generated by the most powerful rocket ever made — but they may also indicate that SpaceX and its CEO Elon
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Some cave dwellers seek isolation to connect with nature or to escape civilization. Learn how Beatrice Flamini’s record-breaking stint as a cave-dweller helped her find her inner resolve.
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A large fight breaks out on the racetrack! #discoveryplus #streetoutlaws Stream Full Episodes of Street Outlaws https://www.discoveryplus.com/show/street-outlaws About Street Outlaws: Street Outlaws explores the world of street racing in Oklahoma City where, after throwing out the top 10 list, the 405 competes in a high-speed, high-stakes qualifier for a chance to race in America’s List. Subscrib
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California’s superblooms are amazing, but also fragile. Researchers have guidance for how to preserve the native flowers and landscape for the future. “Superblooms are difficult to manage because they don’t occur every year,” says Joan Dudney , an assistant professor in the University of California, Santa Barbara’s Environmental Studies Program and Bren School of Environmental Science & Managemen
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Computer simulations have helped researchers understand in detail how pharmaceutically active substances cross cell membranes. These findings can now be used to discover new drug candidates more efficiently. There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective . Chemists and pharmaceutical scientists are franticall
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In March 2018 at the Ol Pejeta Conservancy in Kenya, surrounded by his devoted keepers, Sudan the northern white rhino breathed his last. He wasn’t the only remaining northern white rhino because three females in protective captivity survived him. But Sudan’s death ended any hope of those females breeding naturally and rendered the northern white rhino effectively extinct. Source
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Can you imagine a car company putting a new vehicle on the market without built-in safety features? Unlikely, isn’t it? But what AI companies are doing is a bit like releasing race cars without seatbelts or fully working brakes, and figuring things out as they go. This approach is now getting them in trouble. For example, OpenAI is facing investigations by European and Canadian data protection au
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Today, electronic and photonic devices are ubiquitous in smart phones, computers, light sources, sensors, and communications. To underpin the demand for optoelectronic applications, functional materials are essential. For instance, silicon is required for logic computing and photonic integrated circuits (PIC); group III-V semiconductors (such as GaAs, InP, AlN, etc.) are used for optoelectronic, l
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In his new book, Nicholas Mirzoeff explains how visual culture has upheld white supremacy—through art, monuments, and surveillance—and offers ways to dismantle it. The phrase “white supremacy” can evoke images of the Charlottesville rally, Confederate monuments, and police brutality. But what if white supremacy is also perpetuated through classic works of art, face masks, or drones? According to
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Plant-associated microbes play an important role in host nutrient utilization, stress tolerance, plant health, and adaptation. Identifying the key mucilage compound and friendly microbe, as well as their protective association with diazotrophic microbiota, is of great value in understanding the microbial homeostasis of the mucilage-microbiota system.
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Anthocyanins are important health-promoting pigments that contribute significantly to the nutritional and commercial value of fruits. The anthocyanin biosynthetic pathway is well understood and the key regulatory genes controlling the pathway have been identified in fruits. Anthocyanin accumulation is controlled by developmental, environmental and hormonal cues. Understanding the molecular mechani
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A recent study published in Sensors and Actuators: B. Chemical highlights the development of highly active oxidase mimics using MnOx nanobelts (NBs) generated through laser irradiation in liquid (LIL) techniques by researchers from Institute of Solid State Physics, Hefei Institute of Physical Sciences, Chinese Academy of Sciences.
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Plant-associated microbes play an important role in host nutrient utilization, stress tolerance, plant health, and adaptation. Identifying the key mucilage compound and friendly microbe, as well as their protective association with diazotrophic microbiota, is of great value in understanding the microbial homeostasis of the mucilage-microbiota system.
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The enormous expense of these rockets could have been spent on addressing the many crises that we face on our fragile planet One strong argument in favor of heavily taxing the super-rich is that billionaires so often seem to have profoundly misguided ideas about how to spend their money. They waste it on solid gold toilets, or – like the Sacklers and the Russian oligarchs supporting Putin’s war –
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Anthocyanins are important health-promoting pigments that contribute significantly to the nutritional and commercial value of fruits. The anthocyanin biosynthetic pathway is well understood and the key regulatory genes controlling the pathway have been identified in fruits. Anthocyanin accumulation is controlled by developmental, environmental and hormonal cues. Understanding the molecular mechani
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Cells are expert cooperators and collaborators. To maintain tissue health, cells talk to each other, exert pressure on each other, and kick out cells that are not contributing to the overall well-being of the collective. When it's time to get rid of a cell, the collective group initiates a process called cell extrusion. Cells can be extruded for a number of reasons—they could be cancerous, or old,
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An MUSC Hollings Cancer Center research team has identified a protein that helps cancer cells to organize themselves in a way that allows them to successfully navigate the cell division process despite an abnormality that should doom them. Targeting this protein could throw the cancer cells into disarray, leading to cell death among the cancer cells while leaving normal cells untouched, the resear
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Each year approximately 10 million waterfowl fly north to their breeding grounds in the Prairie Pothole Region of North America, but the landscape that greets them has changed. Weather patterns and agricultural practices have significantly transformed the pothole-dotted native grasslands that waterfowl have used for thousands of years.
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Detailed examinations of the heart have revealed the pivotal role of the left ventricle—it's the area of the heart that develops first and provides the force to pump blood around our bodies. Crucially, it is also the area most commonly implicated in heart disease and heart attacks and it is the area most prone to suffering the cardiotoxic effects of certain drugs.
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Cells are expert cooperators and collaborators. To maintain tissue health, cells talk to each other, exert pressure on each other, and kick out cells that are not contributing to the overall well-being of the collective. When it's time to get rid of a cell, the collective group initiates a process called cell extrusion. Cells can be extruded for a number of reasons—they could be cancerous, or old,
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An MUSC Hollings Cancer Center research team has identified a protein that helps cancer cells to organize themselves in a way that allows them to successfully navigate the cell division process despite an abnormality that should doom them. Targeting this protein could throw the cancer cells into disarray, leading to cell death among the cancer cells while leaving normal cells untouched, the resear
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Each year approximately 10 million waterfowl fly north to their breeding grounds in the Prairie Pothole Region of North America, but the landscape that greets them has changed. Weather patterns and agricultural practices have significantly transformed the pothole-dotted native grasslands that waterfowl have used for thousands of years.
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Detailed examinations of the heart have revealed the pivotal role of the left ventricle—it's the area of the heart that develops first and provides the force to pump blood around our bodies. Crucially, it is also the area most commonly implicated in heart disease and heart attacks and it is the area most prone to suffering the cardiotoxic effects of certain drugs.
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Sara Petersen’s new book explores the ways influencers shape our ideas about motherhood. But she lets her mega-influential subjects off the hook.
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A team of international researchers led by Federico Baltar of the University of Vienna and José M González of the University of La Laguna has identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters. The results have now been pub
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A research team led by Prof. Yang Liangbao from Hefei Institutes of Physical Science, Chinese Academy of Sciences found that hexagonal boron nitride (h-BN) could effectively block electron tunneling and extend the ultimate plasmonic enhancement limits in a single-atom-layer gap, providing deep insights into quantum mechanical effects in plasmonic systems and enabling potential novel applications b
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MIT engineers have designed a two-component system that can be injected into the body and help form blood clots at the sites of internal injury. These materials, which mimic the way that the body naturally forms clots, could offer a way to keep people with severe internal injuries alive until they can reach a hospital.
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Thank you for joining us on “The cloud hub: From cloud chaos to clarity.” Companies are collecting and sharing a growing amount of sustainability data, but they often fail to take advantage of the benefits that their data can provide. This critical cycle of collection and sharing can lead to insights that improve ESG outcomes and help enterprises achieve their business goals. Click here to contin
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A team of international researchers led by Federico Baltar of the University of Vienna and José M González of the University of La Laguna has identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters. The results have now been pub
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Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation. The strategy allows a synthesis of highly activatable Raman probes with high aggregation and multiplexing ability, making it a promising tool for e
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Worms exposed to a cannabinoid become even more interested in the kind of food that they’d already prefer, new research shows. The effect is similar to craving potato chips and ice cream after a few puffs of marijuana, a phenomenon known scientifically as “ hedonic feeding ” but colloquially called “the munchies.” The findings point to worms as a useful tool for understanding more about the many
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This is today’s edition of The Download , our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The first babies conceived with a sperm-injecting robot have been born Last spring, a group of engineers set out to test the sperm-injecting robot they’d designed. One of the team, with no real experience in fertility medicine, used a Sony PlayStation 5 contro
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Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation. The strategy allows a synthesis of highly activatable Raman probes with high aggregation and multiplexing ability, making it a promising tool for e
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Recently, Professor Wu Dayu of Changzhou University, the user of China's Steady High Magnetic Field Facility (SHMFF), Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS), together with his collaborators proposed a facile mechanical strategy to optimize the electronic structures of the catalytic center by mechanically induced spin transition, and realized a new met
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There’s significant variation in the anatomy of the human digestive system, with pronounced differences possible between healthy individuals, research shows. The finding has implications for understanding the role that the digestive tract’s anatomy can play in affecting human health, as well as providing potential insights into medical diagnoses and the microbial ecosystem of the gut. “One person
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Blinking is crucial for the eye. It's how animals clean their eyes, protect them, and even communicate. But how and why did blinking originate? Researchers have studied the mudskipper, an amphibious fish that spends most of its day on land, to better understand why blinking is a fundamental behavior for life on land.
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Researchers have designed a tabletop-sized vaccine printer that could be scaled up to produce hundreds of vaccine doses in a day and deployed anywhere vaccines are needed. The vaccine doses are contained within microneedle patches that can be stored long-term at room temperature and applied to the skin, avoiding the need for injections.
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When it comes to technology (and also probably many things) there is a pyramid of ideas. At the very bottom of the pyramid is pure speculation, just throwing out “what if” ideas to feed the conceptual pipeline. A subset of these ideas will pass the sniff test enough to justify some kind of proof-of-concept evaluation. This could be just crunching numbers, or even an experiment to see if the idea
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As the race for the GOP presidential nomination gets under way, the party’s ideological divisions are sharpening. Consider the opening salvo of Donald Trump’s third Republican presidential campaign. The former president and his allies have fusilladed Ron DeSantis over the Florida governor’s past support for curbing the growth of Medicare and Social Security spending, echoing a similar line of att
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F irst, some swashbuckling. The journalist David Grann embarks on a multi-leg journey from New York to Florida to Santiago, an annoying combination of planes and customs and cars and ferries en route to Chiloé Island, a little strip off the coast of Chile. There, he meets the boat captain who has agreed to steer him hundreds of miles farther south, to Wager Island, a place where nobody lives. Sto
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Energetic quasiparticles possess a collection of quantum characteristics that operate in a particle-like way in superconducting nanostructures, and they can undergo relaxation by involving many cascaded interactions between electrons, phonons and Cooper pairs. These interactions are significant to the performance of devices such as qubits or photon detectors, yet they remain to be well understood
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TikTok CEO Shou Chew dives into how the trend-setting video app and cultural phenomenon works — from what distinguishes its algorithm and drives virality to the challenges of content moderation and digital addiction. In a wide-ranging conversation with head of TED Chris Anderson, he tells stories about the TikTok creators he loves and digs into thorny issues like data privacy and government manipu
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Förmaksflimmer är ovanligt hos barn och unga, men personer som föddes för tidigt, eller som var stora vid födseln, har en förhöjd risk att drabbas i vuxen ålder. Det visar en studie. Inlägget dök först upp på forskning.se .
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We are pleased to present an excerpt from Distrust: Big Data, Data-Torturing, and the Assault on Science , a new book by Pomona College economics professor Gary Smith . The Washington Post said the book’s lessons “ are very much needed .” The fact that changes in bitcoin prices are driven by fear, greed, and manipulation has not stopped people from trying to crack their secret. Empirical models o
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Nature Communications, Published online: 25 April 2023; doi:10.1038/s41467-023-38114-3 The ability to regulate membrane pore size as needed has been a topic of active research for developing next-generation stimuli-responsive smart membranes. Herein, the authors report the observation of operando regulation of the pore size of A membrane based on electro-osmotic swelling.
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De kommende års rekrutteringsudfordringer inden for STEM-fagene kan kun løses, hvis flere kvinder tager disse uddannelser, trodser indgroede mekanismer og fordomme og får mulighed for at fastholde STEM-interessen på længere sigt. Et stærkt netværk af rollemodeller viser sig ifølge Rambøll-evaluering at være et afgørende redskab til at skabe forandring.
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I see no end of articles arguing for and against the extinction of the software developer now GPT is advancing. As with most divisive debates, my expectation is that, at least in the short to mid term, the truth is probably going to be somewhere in between. I’m an iOS developer and am fully expecting the job market to be tougher once GPT (or something like it) gets its claws in and companies look
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With how powerful Chat GPT already is and how powerful future AI tools will be, how will we use a tool so powerful to do good instead of bad? Also, what past events in history have pointed signs towards how we might handle where we are on this threshold of AI technology getting far more advanced soon? How can/will we use these tools to better society? submitted by /u/Karl0r [link] [comments]
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Are you looking to leverage data engineering services and take your business to the next? Then you can put an end to your search with Systango. Systango is a leading data engineering service provider that offers innovative and reliable solutions to help businesses transform their data into valuable insights. With years of experience in data engineering, Systango provides a range of services inclu
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Nature Communications, Published online: 25 April 2023; doi:10.1038/s41467-023-37811-3 IgE antibodies targeting cancer antigens can be used for immunotherapy. Here the authors present an IgE antibody targeting the melanoma-associated antigen, chondroitin sulphate proteoglycan 4, that recognises human melanoma, stimulates tumour cell cytotoxicity, and restricts tumour growth in humanised mouse mod
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Den framgångsrika minskningen av utsläpp per capita som skett i höginkomstländer utplånas av den ökning av befolkningen som samtidigt ägt rum där. En ökad befolkning är den främsta pådrivaren bakom ökade koldioxidutsläpp, enligt forskare som studerat 30 års utsläppsdata. Inlägget dök först upp på forskning.se .
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Joshua Bergen is a very productive person. His secret is the workspace app Notion. Bergen, a product manager living in Vancouver, uses it to plan trips abroad in meticulous detail, with notes and timelines. He uses it to curate lists of the movies and TV shows he’s watched, and records what he thought of them. It’s also a handy way to keep tabs on his 3D-printing projects, map snowboarding runs,
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Nature, Published online: 24 April 2023; doi:10.1038/d41586-023-01430-1 More than 40 editors from two neuroscience journals quit in protest against author fees. Plus, Tasmanian devil facial tumours emerged a decade before detection and why we all misremember the same stuff.
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Nature, Published online: 21 April 2023; doi:10.1038/d41586-023-01420-3 Caenorhabditis elegans spends a lot of time eating after soaking in an endocannabinoid bath. Plus, stem-cell malfunction causes grey hair and how to prepare your lab for natural disasters.
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Last spring, engineers in Barcelona packed up the sperm-injecting robot they’d designed and sent it by DHL to New York City. They followed it to a clinic there, called New Hope, where they put the instrument back together, assembling a microscope, a mechanized needle, a tiny petri dish, and a laptop. Then one of the engineers, with no real experience in fertility medicine, used a Sony PlayStation
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One January afternoon last year, a bouquet of balloons arrived at Karen Rose’s residence in Delray Beach, Florida. She wasn’t expecting a delivery, since it wasn’t her birthday or wedding anniversary, and she thought someone had made a mistake until she noticed the words “AND NOW?” printed on each balloon. “AND NOW?” is the prompt that follows every action on ECHO, a 34-year-old text-based social
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Sydliga fåglar som steglits och brandkronad kungsfågel blir allt vanligare. Samtidigt pressas storspov och rödvingetrast norrut. Högre temperaturer ritar om den svenska fågelkartan, visar en ny rapport. Inlägget dök först upp på forskning.se .
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Nature Communications, Published online: 25 April 2023; doi:10.1038/s41467-023-38031-5 Understanding mechanisms of PLpro substrate selectivity offers new ways to decouple substrate activities and will inform new therapeutic strategies. Here, the authors use multi-disciplinary approaches to uncover how PLpro from SARS-CoV-2 can discriminate between different substrates.
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Nature Communications, Published online: 25 April 2023; doi:10.1038/s41467-023-37840-y Brain microvascular dysfunction occurs in Alzheimer’s disease and other taupathies. Here the authors show that soluble pathogenic tau accumulates in brain microvascular endothelial cells of P301S(PS19) mice modeling tauopathy, and that it contributes to vascular deficits in these mice.
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Competition to claim a market that could be worth $100 billion a year for drugmakers alone has triggered a wave of advertising, provoking concern from regulators and doctors worldwide. But their tools for curbing the ads that go too far are limited — especially when it comes to social media.
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Nature Communications, Published online: 25 April 2023; doi:10.1038/s41467-023-37905-y The spatial distribution of cellular compartments within the tumour microenvironment in non-small cell lung cancer (NSCLC) remains to be investigated. Here, the authors identify distinct cell populations of tumour cells and tumour-associated immune cell phenotypes with different spatial distributions in NSCLC.
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Rather than board the injection bandwagon, Britain should be taxing unhealthy food and clamping down on marketing Humankind has been freed from the threat of disease by some wonderful, transformative inventions, from smallpox injections to the Covid vaccinations. With all due respect, I don’t think the so-called skinny jab is one of them. A boom in injectable weight-loss drugs, such as Wegovy fro
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In 2019, Drs. John Mandrola, Adam Cifu, Vinay Prasad, and Andrew Foy wrote an article titled The Case for Being a Medical Conservative. They wrote that the “choice of the term ‘medical conservative’ does not imply a political philosophy.” Instead, they recognized “that many developments promoted as medical advances offer, at best, marginal benefits”. The crux of their article was that: The medica
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This is a re-post from Yale Climate Connections by Kristen Pope The three biggest wildfires in Colorado’s recorded history roared through the state during one year in 2020, burning more than a half million acres of forests. The Cameron Peak Fire raged for close to four months, encompassing more than 208,000 acres. The East Troublesome covered 193,000 acres and the Pine Gulch fire 139,000. Blacken
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Experts and campaigners have been pointing out the racial disparities in maternal healthcare for years. The latest report to highlight the issue comes from the UK government’s women and equalities committee. MPs behind the report have condemned the government’s failure to address the gulf in outcomes. So why are black and Asian women still more at risk from childbirth? Madeleine Finlay hears what
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Experts and campaigners have been pointing out the racial disparities in maternal healthcare for years. The latest report to highlight the issue comes from the UK government’s women and equalities committee. MPs behind the report have condemned the government’s failure to address the gulf in outcomes. So why are black and Asian women still more at risk from childbirth? Madeleine Finlay hears what
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Researchers have designed a tabletop-sized vaccine printer that could be scaled up to produce hundreds of vaccine doses in a day and deployed anywhere vaccines are needed. The vaccine doses are contained within microneedle patches that can be stored long-term at room temperature and applied to the skin, avoiding the need for injections.
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why's the world so hell-bent on destroying the already present structures and way of working? I am all for progress and I think AI is good – but there are so many problems that need much more attention. Also, what markets do you think will emerge from such a rapid shift? Not everyone wants to research AI, and neither does everyone enjoy sitting on their PC and code. I feel the current rapid AI de
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The final moments of Tucker Carlson’s last Fox News broadcast are perfect. His studio desk is strewn with pizza boxes. Across from him is the delivery man who’d traveled from Pennsylvania to bring him his favorite slice: sausage and pineapple. “It is a disgusting order, but I have no shame,” Carlson says with this mouth full, grinning. He then turns to the camera to wrap the broadcast with one fi
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This is an edition of The Atlantic Daily, a newsletter that guides you through the biggest stories of the day, helps you discover new ideas, and recommends the best in culture. Sign up for it here. Most Americans do not want President Joe Biden and former President Donald Trump in another head-to-head match for the White House. But barring a dramatic change in circumstances, that’s the contest we
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Study suggests antimicrobial used to promote livestock growth breeds bacteria more resistant to our natural defences The blanket use of antibiotics in farming has led to the emergence of bacteria that are more resistant to the human immune system, scientists have warned. The research suggests that the antimicrobial colistin, which was used for decades as a growth promoter on pig and chicken farms
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Digital transformation has become more than a mantra for organizations that want to stay competitive in today’s ever-shifting global business landscape. Digital technologies, including artificial intelligence (AI) and robotics, are increasingly embedded in key areas of businesses to improve processes, satisfy fluctuating consumer demands, and boost operational resilience in times of uncertainty.
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Large trees offer major solutions to the climate and biodiversity crisis that are needed now. As President Biden calls for protecting mature and old growth trees on Federal lands, the study describes synergies between protecting these disproportionately valuable large trees and forest resilience goals, providing common solutions for these urgent challenges.
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Sharing Royalties While some music artists and their labels are increasingly becoming wary of those using AI models to clone their voices, others are choosing to ride the wave and embrace an AI-filled future. Experimental artist and futurist Claire "Grimes" Boucher, for one, is looking at the new trend as an opportunity. "I'll split 50 percent royalties on any successful AI-generated song that us
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Breaking the Mould A University of Victoria academic used ChatGPT in a fascinating way to write a recommendation letter for a student, The Atlantic reports — and it worked so well that it helped the student win a prestigious Cambridge scholarship. "A dirty secret of academe is that most professors have a cache of letters separated into different categories," Matt Huculak, the head of advanced res
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Large trees offer major solutions to the climate and biodiversity crisis that are needed now. As President Biden calls for protecting mature and old growth trees on Federal lands, the study describes synergies between protecting these disproportionately valuable large trees and forest resilience goals, providing common solutions for these urgent challenges.
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Polycyclic aromatic hydrocarbons (PAHs) are typical organic compounds found in cigarette smoke and vehicle exhaust. In addition, PAHs are produced from incomplete combustion of organic material and cooking. The highest concentrations of PM-bound PAHs ranged from 550 ng/m3 to 39,000 ng/m3, and have been observed in Chinese kitchens, fire stations, and ships.
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The measures to contain the COVID-19 pandemic and the challenges associated with it have temporarily put a strain on the quality of partnerships, but results of the German Ageing Survey show that already in the winter of 2020/21 people rated their couple relationship almost as good again as before the pandemic. For women, however, the losses in partnership quality were not only particularly high:
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Cancer is a complex systemic disease, with accompanying secondary effects that can result in debilitating effects on the human body. Cancer-associated skeletal muscle weakening or loss, also called "cancer cachexia," is a prevalent and serious condition responsible for 20%–30% of the deaths in affected cancer patients. In current treatments for cancer cachexia, there are limitations in efficacy le
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Interest rate variance risk premium (IRVRP), the difference between implied (forward-looking) and realized (backward-looking) variances of interest rates, measures compensation for risk for exposure to volatility in the interest-rate markets.
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The Haber-Bosch process is the industrial approach for NH3 production today, which must be operated at energy-intensive high temperatures and pressures. The reduction of dinitrogen (N2) by electrocatalysis offers an alternative way for NH3 production at ambient conditions and a variety of electrocatalysts have been studied over the past few years.
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Autologous and allogeneic bone grafts are considered the gold standard when it comes to reconstructing bones, largely due to their bioactive compounds and osteoblastic cells that can generate new bone effectively. However, limited supply, donor-site complications, and risk of disease transmission have deterred its widespread use.
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Plant diseases pose a significant threat to nations across the globe, owing to the financial burden they impose and the impact they have on food security. Healthy crops sustain millions of livelihoods, and accurate diagnosis of plant diseases allows for timely interventions to ensure sufficient crop production with minimal yield loss.
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The ionosphere—the region of geospace spanning from 60 to 1000 kilometers above the Earth—impairs the propagation of radio signals from global navigation satellite systems (GNSS) with its electrically charged particles. This is a problem for the ever higher precision required by these systems—both in research and for applications such as autonomous driving or precise orbit determination of satelli
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Plant diseases pose a significant threat to nations across the globe, owing to the financial burden they impose and the impact they have on food security. Healthy crops sustain millions of livelihoods, and accurate diagnosis of plant diseases allows for timely interventions to ensure sufficient crop production with minimal yield loss.
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Nature Communications, Published online: 24 April 2023; doi:10.1038/s41467-023-38104-5 The lateral flow assay (LFA) has been considered a rapid test tool but with low sensitivity hampering the precise diagnosis. Here, the authors report bioengineered enrichment tools for LFAs with enhanced sensitivity and specificity that can reinforce LFA’s clinical performance.
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